Property Summary

NCBI Gene PubMed Count 23
PubMed Score 43.10
PubTator Score 15.88

Knowledge Summary


No data available


  Differential Expression (15)

Disease log2 FC p
glioblastoma 1.800 1.6e-02
posterior fossa group A ependymoma 4.400 2.1e-09
sonic hedgehog group medulloblastoma 4.000 4.5e-04
primary pancreatic ductal adenocarcinoma 1.530 5.4e-04
pancreatic cancer 1.500 5.3e-04
interstitial cystitis -1.500 1.2e-03
adult high grade glioma 2.400 8.4e-03
non primary Sjogren syndrome sicca -1.100 2.1e-02
nasopharyngeal carcinoma 1.800 5.9e-03
Breast cancer -4.200 6.8e-25
breast carcinoma -1.800 4.4e-38
gastric carcinoma 1.800 2.5e-02
ulcerative colitis -1.300 3.3e-04
ovarian cancer -2.500 1.3e-03
head and neck cancer -1.800 1.4e-02

 GO Component (1)

 GWAS Trait (1)

Gene RIF (3)

24127533 aim of this work was to search for mutations in thyroid developmental candidate genes HOXA3, HOXB3, HOXD3 and PITX2
19453261 Observational study of gene-disease association. (HuGE Navigator)
17972163 HOXA7, HOXB3, HOXA3, and HOXB13 expression levels changed during angiogenesis, sugessting these proteins might be involved in the angiogenesis of hMSCs.

AA Sequence

YTDLTGHHPSQGRIQEAPKLTHL                                                   421 - 443

Text Mined References (24)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
25108383 2014 Genome-wide association analyses identify variants in developmental genes associated with hypospadias.
24127533 2014 The absence of mutations in homeobox candidate genes HOXA3, HOXB3, HOXD3 and PITX2 in familial and sporadic thyroid hemiagenesis.
21516116 2011 Next-generation sequencing to generate interactome datasets.
19453261 2009 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17972163 2009 HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells.
17567994 2007 Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
16959974 2006 The consensus coding sequences of human breast and colorectal cancers.
16582099 2006 The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12853948 2003 The DNA sequence of human chromosome 7.
12690205 2003 Human chromosome 7: DNA sequence and biology.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11857506 2002 Complete mutation analysis panel of the 39 human HOX genes.
11823429 2002 Krox20 and kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain.
9894676 1998 Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1.
9847074 1998 Toward a complete human genome sequence.
9520319 1998 Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands.
8889548 1996 Normalization and subtraction: two approaches to facilitate gene discovery.
8646877 1996 Fine mapping of human HOX gene clusters.
1973146 1990 Nomenclature for human homeobox genes.
1358459 1992 Vertebrate homeobox gene nomenclature.