HMG20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
Protein Summary
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
- ENST00000333651
- ENSP00000328269
- ENSG00000064961
- BRAF35
- HMGX2
- HMGXB2
- SMARCE1R
- SOXL
- HMGX2
- BRAF25
- BRAF35
- HMGXB2
- PP7706
- pp8857
- SMARCE1r
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.84 | ||
histone modification site profile | 0.83 | ||
protein complex | 0.74 | ||
biological process | 0.72 | ||
transcription factor | 0.69 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 19.62 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 274 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 19.62 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 274 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0