| Tbio | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related |
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 5112 | 2.3e-11 |
| oligodendroglioma | 2850 | 2.7e-11 |
| glioblastoma | 5792 | 3.5e-09 |
| adult high grade glioma | 3801 | 1.1e-05 |
| ovarian cancer | 8520 | 1.3e-05 |
| medulloblastoma | 720 | 2.4e-04 |
| psoriasis | 6694 | 3.2e-04 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 5.0e-04 |
| Down syndrome | 499 | 9.9e-04 |
| COPD | 118 | 1.1e-03 |
| ependymoma | 4679 | 1.8e-03 |
| osteosarcoma | 7950 | 2.2e-03 |
| Multiple myeloma | 1332 | 5.6e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 8.0e-03 |
| primitive neuroectodermal tumor | 3035 | 1.1e-02 |
| astrocytic glioma | 2597 | 2.2e-02 |
| subependymal giant cell astrocytoma | 2287 | 2.3e-02 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 2.9e-02 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | 1.200 | 1.1e-05 |
| astrocytic glioma | 1.300 | 2.2e-02 |
| atypical teratoid / rhabdoid tumor | 1.800 | 2.3e-11 |
| COPD | -1.100 | 1.1e-03 |
| Down syndrome | 1.100 | 9.9e-04 |
| ependymoma | 1.800 | 1.8e-03 |
| glioblastoma | 1.300 | 3.5e-09 |
| intraductal papillary-mucinous adenoma (... | 1.100 | 8.0e-03 |
| intraductal papillary-mucinous carcinoma... | 1.900 | 5.0e-04 |
| intraductal papillary-mucinous neoplasm ... | 1.200 | 2.9e-02 |
| medulloblastoma | 1.200 | 2.4e-04 |
| Multiple myeloma | 1.109 | 5.6e-03 |
| oligodendroglioma | 1.200 | 2.7e-11 |
| osteosarcoma | 1.553 | 2.2e-03 |
| ovarian cancer | 2.300 | 1.3e-05 |
| primitive neuroectodermal tumor | 1.100 | 1.1e-02 |
| psoriasis | 1.100 | 3.2e-04 |
| subependymal giant cell astrocytoma | 1.211 | 2.3e-02 |
MSHGPKQPGAAAAPAGGKAPGQHGGFVVTVKQERGEGPRAGEKGSHEEEPVKKRGWPKGKKRKKILPNGP 1 - 70 KAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDEAEREKQQYMKELRAYQQS 71 - 140 EAYKMCTEKIQEKKIKKEDSSSGLMNTLLNGHKGGDCDGFSTFDVPIFTEEFLDQNKAREAELRRLRKMN 141 - 210 VAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVPGTGETPTLGTL 211 - 280 DFYMARLHGAIERDPAQHEKLIVRIKEILAQVASEHL 281 - 317 //
