1. Home
  2. Targets
  3. HemK methyltransferase family member 1

Tbio HemK methyltransferase family member 1

N5-glutamine methyltransferase responsible for the methylation of the GGQ triplet of the mitochondrial translation release factor MTRF1L.

 Comments

Property Summary

NCBI Gene PubMed Count 6
PubMed Score 16.31
PubTator Score 2.60

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
tuberculosis 2010 8.5e-07
medulloblastoma, large-cell 6241 6.5e-05
osteosarcoma 7950 1.0e-04
ovarian cancer 8520 1.6e-04
psoriasis 6694 1.4e-03
Disease Target Count Z-score Confidence
Leptospirosis 18 4.518 2.3

Expression

  Differential Expression (5)

Disease log2 FC p
medulloblastoma, large-cell 1.100 6.5e-05
osteosarcoma -1.301 1.0e-04
ovarian cancer 1.100 1.6e-04
psoriasis 1.100 1.4e-03
tuberculosis 1.300 8.5e-07

Synonym

Accession Q9Y5R4
Symbols HEMK
MTQ1

Gene

HEMK1

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG Inparanoid

 UniProt Keyword (7)

 GO Function (4)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (13)

 HCA RNA Cell Line (56)

See all...

Gene RIF (2)

AA Sequence 

MELWGRMLWALLSGPGRRGSTRGWAFSSWQPQPPLAGLSSAIELVSHWTGVFEKRGIPEARESSEYIVAH      1 - 70
VLGAKTFQSLRPALWTQPLTSQQLQCIRELSSRRLQRMPVQYILGEWDFQGLSLRMVPPVFIPRPETEEL     71 - 140
VEWVLEEVAQRSHAVGSPGSPLILEVGCGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQRLRLQD    141 - 210
RIWIIHLDMTSERSWTHLPWGPMDLIVSNPPYVFHQDMEQLAPEIRSYEDPAALDGGEEGMDIITHILAL    211 - 280
APRLLKDSGSIFLEVDPRHPELVSSWLQSRPDLYLNLVAVRRDFCGRPRFLHIRRSGP                281 - 338
//

Text Mined References (6)

PMID Year Title