HAUS4
HAUS augmin-like complex subunit 4
Protein Summary
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
- ENST00000206474
- ENSP00000206474
- ENSG00000092036
- ENST00000342454
- ENSP00000342776
- ENST00000347758
- ENSP00000343473
- ENST00000490506
- ENSP00000452260
- ENST00000541587
- ENSP00000441026
- ENST00000555367
- ENSP00000452239
- ENST00000555986
- ENSP00000451018
- C14orf94
- C14orf94
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.87 | ||
kinase perturbation | 0.81 | ||
transcription factor | 0.68 | ||
transcription factor binding site profile | 0.63 | ||
tissue sample | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.4 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 111 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.4 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 111 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0