Property Summary

NCBI Gene PubMed Count 10
PubMed Score 20.50
PubTator Score 5.90

Knowledge Summary


No data available


  Disease (1)

Disease Target Count P-value
psoriasis 6685 1.8e-10


  Differential Expression (1)

Disease log2 FC p
psoriasis -1.400 1.8e-10

 MGI Phenotype (1)

Protein-protein Interaction (4)

Gene RIF (3)

22676722 Results GSTT2B insertion allele was associated with an increased risk of being small for gestational age indicate that
22216261 results suggest that the presence of the recently described GSTT2B deletion may have a protective effect on the risk of OSCC in the Mixed Ancestry South African population
19424424 study describes a previously uncharacterized 38-kilo-base (kb) long deletion polymorphism of GSTT2B located within a 61-kb DNA inverted repeat

AA Sequence

SIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP                                        211 - 244

Text Mined References (16)

PMID Year Title
23533145 2013 In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
22676722 2012 Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes.
22216261 2011 Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control study.
22001757 2011 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
19424424 2009 Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15461802 2004 A genome annotation-driven approach to cloning the human ORFeome.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11181995 2001 The sequence of the human genome.
10591208 1999 The DNA sequence of human chromosome 22.
9729470 1998 Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex.
9551553 1998 Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site.
8761485 1996 The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human.
7789971 1995 Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22.
1417752 1992 Characterization of a human class-Theta glutathione S-transferase with activity towards 1-menaphthyl sulphate.