Property Summary

NCBI Gene PubMed Count 1,965
PubMed Score 1954.91
PubTator Score 2114.63

Knowledge Summary

Patent

No data available

Expression

Synonym

Accession P09488 Q5GHG0 Q6FH88 Q8TC98 Q9UC96
Symbols MU
H-B
GST1
GTH4
GTM1
MU-1
GSTM1-1
GSTM1a-1a
GSTM1b-1b

Gene

PDB

1GTU   1XW6   1XWK   1YJ6   2F3M  

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

MLP Assay (4)

AID Type Active / Inconclusive / Inactive Description
1324 confirmatory 19 / 0 / 815 Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
1769 confirmatory 186 / 0 / 947 Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
602137 other 0 / 0 / 31 Counter screen to determine effect of SAR compounds for Rab7 project on GST-GSH binding, round 1
602145 other 0 / 0 / 12 Counter screen to determine effect of SAR compounds for Rab7 project on GST-GSH binding, round 2

Gene RIF (2389)

PMID Text
27090234 Data show a combined role of cytochrome P 450 1A1 (CYP1A1), Glutathione -S -transferase M1 (GSTM1) and T1 (GSTT1) polymorphisms and smoking status can be attributed for the cause of lung cancer.
27002825 The study showed that polymorphims of the GSTM1 and GSTP1 could impact remission and adverse drug reactions in lupus nephritis treated with cyclophosphamide
26937962 Thus these findings suggest that the three variants of ADH1C, MnSOD and GSTM1 can be used to identify individuals who are at high risk to develop ALD and may be helpful in proper management of Indian alcoholics
26909940 The GSTM1 null genotype has an impact on the increased risk of colorectal carcinoma in Saudi Arabia.
26823865 we suggest that the GSTM1 null genotype and GSTT1 null genotype are correlated with an increased risk of gestational diabetes mellitus in a Chinese population.
26782562 CYP1A1 and GSTM1 gene polymorphisms affect familial aggregation of esophageal cancer among the Kazakh ethnic group in Xinjiang.
26782535 In a subgroup analysis, only the null GSTM1 genotype was observed at a significantly higher frequency in Caucasian varicocele patients. (Meta-analysis)
26782376 The null or present polymorphism of GSTM1 and GSTT1 genes and Arg/Pro of the p53 gene were analyzed.
26681006 The frequency of the absence of the GSTM1 homozygous genotype in the bone tumor patients was markedly higher than that in the control.
26663067 Data suggest that the combined genotypes of glutathionine S-transferase GSTM1 (-/-), GSTT1 (+/+), GSTP1 (AA) and meiotic recombination protein SPO11 (CT) may be associated with idiopathic male infertility in ethnic Han Chinese.
26656529 our meta-analysis suggests there is an association between GSTM1 and GSTT1 polymorphisms and RCC.
26645279 GSTM1 Polymorphisms Predict Recurrence of Non-Muscle-Invasive Bladder Cancer.
26604430 interaction between GSTT1 and GSTM1 genes showed that the combined null genotypes were associated with the risk of UC
26580648 Effect of traditional healthy diet on reduced atopic dermatitis was significant or borderline significant in the GSTM1-present group or the GSTM1/T1 double present group. These associations did not exist in the animal foods and sweets dietary patterns.
26571237 individuals with GSTM1 null genotype and in combination with GSTT1 null and GSTP1 (AG+GG) have a survival advantage in cervical cancer patients
26552558 The frequency of GSTA1, GSTM1 and GSTP1 genotypes was not significantly different between progressive myoclonus epilepsy patients and controls
26548378 association between the combined GSTM1/GSTT1 double-null genotype and advanced liver fibrosis and outcome of chronic HCV infection in Egyptian patients
26535619 This study suggested that the null GSTM1 genotype is associated with BC susceptibility in the Mexican population analyzed.
26529288 GSTM1 null genotype was found to be associated with lung cancer
26456689 Polymorphisms of maternal GSTT1, GSTM1, and GSTP1 may modify the association of maternal smoke exposure with congenital heart defects.
26435566 GSTM1 gene polymorphisms are not associated with susceptibility of developing diabetic neuropathy in T2DM patients.
26434855 A significant association of GSTM1 homozygous null genotype with cervical cancer cases as compared to those with normal cervical cytology was observed in the present study.
26407578 When considered together, GSTM1 and GSTT1 genotypes were found to be associated with an increased risk of breast cancer. The relationship between GSTM1 and GSTT1 gene deletions and breast cancer risk was substantially altered by consumption of Smoked Meat/Vegetable
26406947 These results suggest that GSTM1 and GSTT1 deletion were associated with increased risk of colon and rectum cancer in Pakistani population.
26400343 The GSTM1 polymorphism plays an important role in influencing the chemotherapy response and overall survival in patients with breast cancer.
26370772 This meta-analysis supports that the GSTM1/GSTT1 null genotype might contribute to individual susceptibility to endometriosis in Chinese populations, especially in Chinese Han. [Meta-Analysis]
26350109 GSTM1 null genotype frequency was similar between Brazilian women with and without endometriosis.
26345960 The current study aimed at evaluating the associa-tion between GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms and clinical response to chemotherapy and treatment outcome of breast cancers patients.
26327568 Association of GSTM1 and GSTT1 deletion polymorphisms with Pakistani aplastic anemia patients
26296146 Our results demonstrated a significant association between CSCR and single nucleotide polymorphisms in the CFH gene (rs3753394, rs1329428, and rs1065489), suggesting that disturbances in choroidal vasculature.
26295386 Results revealed that GSTM1, GSTT1, and GSTP1 polymorphisms were not related to risk of schizophrenia, but based on ethnicity, GSTM1 polymorphism showed weak association with schizophrenia in East Asian population. [Meta-analysis]
26288192 GSTM1 null genotype is significantly associated with cardiac iron overload independent of serum ferritin in Egyptian patients with beta thalassemia.
26244436 the C-1562T SNP in the promoter region of the MMP-9 gene, the GSTT1 null, as well as the combined GSTM1 non-null and GSTT1 null genotypes are modulators of temporomandibular disorders risk in a Serbian population
26219826 the meta-analysis suggested that GSTM1 null polymorphism confer the susceptibility to colorectal cancer in Asians, especially in Chinese populations.
26179485 Null-GSTT1 and null-GSTM1 genotypes and Cytochrome P4502E1 (CYP2E1: rs2031920, rs3813867) may support the hematotoxicity of benzene-exposed workers in China, and we can make use of it to select susceptible population
26175060 Authors performed genetic case-control CNV analyses to test for possible associations between schizophrenia and CNVs for the three genes GSTT1, DDTL, and GSTM1 in Japanese patients.
26166128 The results demonstrated that CYP1A1 rs4646903 and null genotype of GSTM1 polymorphisms might serve as risk factors for oral cancer
26163595 GSTM1 Polymorphisms are associated with Hepatic Carcinogenesis.
26158735 GSTM1 null genotype is more frequent in patients with multiple urologic tumors. GSTM1 null genotypes is a risk factor in patients with different types of cancer, with at least one affecting the urinary system.
26150166 Meta-analysis evaluating the associations between multiple sclerosis and polymorphisms of MTHFR, GSTM1, GSTT1, and GSTP1
26125851 The GSTM1 null genotype was associated with breast cancer risk
26125818 Data show a significant difference between the frequency of the GSTM1-null genotype in patients and control groups. However, sub-group analysis found that the GSTM1-null genotype was statistically significant in men, and in Caucasian groups.
26046920 The GSTM1 present genotype was significantly associated with decreased risks of drug-induced liver injury and schizophrenia.
26003511 findings show the null genotypes of GSTM1 and GSTT1 were not associated with risk of heroin dependence(HD); GSTM1-null genotype was not associated with susceptibility to opium dependence(OD);statistical analysis revealed the combination of "positive genotype of GSTM1/null genotype of GSTT1" significantly associated with either HD or OD
25923095 The combined genotypes of GSTM1 null, GSTT1 and GSTP1 105-Val allele were seen to have an increased risk of developing age-related cataract.
25880856 The GSTM1 null genotype was significantly associated with ACS and VOC
25876999 Polymorphisms of GSTT1 and GSTM1 are associated with the methylation of arsenic.
25868597 Meta-analysis revealed slight increase of Parkinson's disease risk in GSTM1 null genotype in subgroup analysis of ethnicity, publication year and sample size of total cases; short of statistical significance was detected for GSTT1 null genotype
25867025 patternized null allele frequencies demonstrated in this study for the first time addresses the missing link in GST M1-T1 null allele frequencies among GAHPs
25809865 GSTM1 promoter methylation is associated with Breast Cancer.
25807650 The results of a case-control study for sporadic cases of colorectal cancer (CRC) show that GSTM1 deletion polymorphisms can have predictive value for susceptibility to CRC.
25799091 GSTM1-null genotype was associated with a lower risk of developing acute childhood leukemia, while GSTP1-GG variants displayed an increased risk, and no differences were found for GSTT1 gene.
25797617 GSTM1 deletion polymorphism may contribute to lung cancer risk in the Chinese population. (Meta-analysis)
25790712 Children with the neutrophilic phenotype of bronchial asthma having deletions in the GSTT1/GSTM1 system are characterized by bronchial hypersensitivity to histamine and dosed physical exercises.
25775823 Polymorphic variants of GSTP1,GSTM1,GSTP1, and NAT2 genes were accociated with development of occupational lung cancer.
25773803 GSTM1 null genotypes is associated with increased risk of prostate cancer in Chinese.
25773790 The GSTM1 deletion polymorphism is not a risk factor for squamous cell carcinoma of the cervix in the northeast Thai women.
25773389 we investigated the relationship between the clinical outcome and the GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms in breast cancer patients with chemotherapy.
25735346 GSTM1 gene variants are associated with the risk of developing oral cancer in tobacco addicted patients.
25730077 GSTM1 polymorphisms are not associated with lung cancer risk [meta-analysis]
25725180 the increased frequencies of GSTM1 null in patients with primary closed angle glaucoma (PCAG) could be associated with a risk factor for incidence of PCAG in the Iranian population
25724184 Smokers carrying CYP1A1 TC/CC + GSTM1 null and CYP1A1 TC/CC + GSTT1 null genotypes showed significant association with head and neck cancer risk
25697264 Its genotype in cervical cell samples may be associated with more severe precancerous lesions of the cervix in a Japanese population.
25663492 The null genotype of GSTM1 exhibited a significantly higher percentage in patients with squamous cell carcinoma of cervix (74 %) than in the control group (34.0 %).
25654087 The aim of the study was to assess whether selected single nucleotide polymorphisms of CYP1A1 and 2E1, GSTM1, GSTT1, and SULT1A1 influence susceptibility towards hepatocellular carcinoma.
25628002 The null polymorphism of the GSTM1 or GSTT1 genes is not associated with susceptibility to systemic lupus erythematosus. (Meta-analysis)
25565670 GST genotyping before hematopoietic stem cell transplantation may allow better prediction of busulfan pharmacokinetics and drug toxicity, and thereby improve outcome after busulfan and cyclophosphamide conditioning
25549292 gene deficiency predisposes to endometriosis in a Tunisian population
25532576 The effect of GSTM1 and/or GSTT1 (especially the former) is underrated in modulating the risk of male infertility in males from Sichuan, Southwest China.
25525805 Results did not support the GSTM1 and GSTT1 polymorphisms as the predictors of anti-tuberculosis drug induced hepatotoxicity in Chinese Han children treated with anti-tuberculosis drugs.
25472599 oxidative damage may be play a important role in patients with N-SCLC, and that GSTM1 and glutathione S-transferase M1 and T1 genes genotypes may predispose the cells of patients with non-small lung cancer to increased oxidative damage
25461363 Meta-analysis provides strong evidence that the GSTM1 and GSTT1 polymorphisms are associated with the development of endometriosis.
25450282 The GSTM1 polymorphism is not contributed to the risk of ovary cancer from currently available evidence.
25445355 STin2, GSTM1, and GSTT1 polymorphisms, and PON1 status would be associated with comorbid tobacco use + mood disorders.
25443469 GSTM1 null genotype increases the overall risk of endometriosis. [meta-analysis]
25432134 We found a significant interaction between the GSTT1 and GSTM1 genotypes with regard to esophageal squamous cell carcinoma risk (P = 0.001); however, there were no interactions between environmental factors and GSTT1 and GSTM1 genotypes
25420021 Data show there were combined effects of glutathione S-transferase GSTM1 and GSTT1 genotypes and fruit & vegetable intake on cognitive function in the elderly population.
25408579 The GSTM1 null and GSTT1 null genotypes, which resulted in a significantly increased risk when analyzed separately, showed a stronger risk association when analyzed in combination.
25395496 polymorphisms of NQO1, CAT, and GSTM1 are involved in modulation effect of sodium arsenite on chromosomal aberration indices
25378345 A meta-analysis to determine the association between chronic pancreatitis and glutathione-S transferase (GST) mu 1 (GSTM1) and theta 1 (GSTT1) deletions.
25375048 The research on GSTM1 protein, human consisted in patients diagnosed with multiple breast cancers.
25366778 Data indicate that the combined glutathione S-transferases GSTM1 null and GSTT1-present genotypes were more frequent in the primary open-angle glaucoma group compared to the control group.
25357227 It is concluded that ACE (rs 4646994), FABP2 (rs1799883) and GST (GSTM1 null or positive genotype and GSTT1 null or positive genotype) genes polymorphism are associated with essential hypertension.
25348056 GSTM1, GSTT1 and GSTP1 genes are collectively involved in the development of idiopathic male infertility and their phenotypic effects on the disease risk are potentiated by cigarette smoking.
25341249 Polymorphism of studied GST genes (GSTM1,GSTT1 and GSTP1) and various combinations of polymorphic variants did not affect the risk of BPD developing
25328891 This study demonstrates that the GSTM1 null genotype presents a protective effect against asthma development in girls, but the risk of asthma development increases significantly under prenatal TSE.
25305053 Maternal null GSTM1 was associated with a 144 g (95% CI, -291, 1) and combined maternal/infant null GSTT1 was associated with a 155 g (95% CI, -303, -8) decrease in birth weight
25292056 GSTM1 polymorphisms are associated with lung cancer risk.
25283245 A differential involvement of GSTM1 and MRP1 in acquired resistance to VAs.
25281494 Women who were polymorphic for CYP1A1 experienced an HR-HPV clearance rate that was 20% lower than women without the polymorphism for CYP1A1. The GSTM1 null genotype was associated with higher HR-HPV clearance rate.
25251951 The distribution of genotype frequencies for GSTM1, GSTT1, and GSTP1 I105V polymorphisms were not associated with risk of prostate cancer in the study sample
25249451 case-control study for sporadic cases of colorectal cancer(CRC)in Kazakhstan shows some polymorphisms can have predictive value for susceptibility to CRC; there are 2 important genotypes:TP53 homozygous Pro72Pro (mixed population OR=3.80, p<0.0001) and GSTM1 deletions (mixed population- OR=1.83, p=0.001)
25208225 null genotypes of GSTM1 and/or GSTT1 contribute to risk of endometriosis
25198353 Copy number variation of GSTT1 and GSTM1 and the risk of prostate cancer in a Caribbean population of African descent
25183432 GSTM1 null genotype is associated with an increased coronary artery disease risk.
25130880 Results of this study suggest a possible negative effect of GSTM1 null genotype on the spermatogenic potential of the testis.
25118837 Allergen-induced neutrophilic airway inflammation in GSTM1+ asthmatics is associated with NF-kappaB activation in airway epithelial cells in vivo.
25102096 Studies indicate that glutathione S-transferases GSTM1 and GSTT1 null genotypes were associated with increased risk of childhood acute lymphoblastic leukemia (ALL), which was not associated with GSTP1 genotype.
25101770 Using log-transformed whole blood arsenic concentrations as the dependent variable in a General Linear Model, there was a significant interaction between GSTP1 and autism spectrum disorder case status, but not for GSTT1 and GSTM1.
25080812 respect to a deletion of the Glutathione-S-transferase M1 gene. In this study, we evaluated the relationship between the GSTM1 gene deletion and genetic diversity of the GSTM cluster, which includes this gene, in three Russian populations.
25080784 The association of risk of development of cardiomyopathies with polymorphic variants of genes of angiotensin converting enzyme, glutathione-S-transferase, interleukins 8 and 10
25040976 To identify the genotypes of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 in a case-control study.
25036724 associations between two vital GSTs genetic polymorphisms and lung cancer risk in the Chinese population
25033877 GSTM1 null genotype was significantly associated with lung cancer risk in a meta-analysis of Asian populations.
25027672 induced expression in human monocytes following exposure to Aflatoxin B1
25027082 No significant association and gene dosage effect of GSTM1 gene copy number with lung cancer risk ( P trend =0.13) were found.
25015263 study of risk association of GST M1 and GST T1 genotypes with head and neck cancer in tobacco users in India
25010410 25.8% of the infertile women and 0% of the controls had the GSTM1 null genotype
24998552 GSTM1 null genotype is not associated with hepatocellular carcinoma susceptibility.
24994605 The GSTM1/GSTT1 double-null genotype was significantly associated with response after the first course of induction chemotherapy in AML. Review.
24970787 These genotyping finding revealed that the absence of GSTM1 activity could be contributor factor for the development of epilepsy disease.
24948179 Review/Meta-analysis: GSTM1 null genotype contributed to the development of gastric cancer.
24938875 Data indicate that both cytochrome P450 1A1 (CYP1A1) MspI and glutathione S-transferase M1 (GSTM1) genetic polymorphisms were independently associated with the risk of lung cancer.
24919441 This study supports hypothesis that GSTM1 null genotype may be a moderate BC risk factor.
24914957 The role of the glutathione S-transferase A1, M1, P1 and T1 gene polymorphisms and potential effect modification by occupational exposure to different chemicals in Serbian bladder cancer male patients, was investigated.
24913811 Chronic myeloid leukemia patients carrying the GSTT1 present/GSTM1 present genotype are less resonsive to imatinib and the interaction between GSTT1 and GSTM1 seems to influence treatment outcome.
24908960 In patients with neutrophilic bronchial asthma and polymorphism of genes GSTT1 and GSTM1 there was a tendency to decreasing the bronchial lability index through the decreased bronchodilation.
24903797 GSTM1 'null' mutation were not associated with risk of antitubercular agent-induced hepatotoxicity in a north Indian population.
24854448 These findings indicate that genetic variants of GSTTI and GSTM1 significantly increase the risk of developing AML. Our study offers important insights into the molecular etiology of AML.
24852519 The absence of GSTM1 and GSTT1 genes increases the risk of lung cancer because of radon exposure.
24852428 suggests that there would be no direct interaction of GSTM1 and GSTT1 genotype in hepatocellular carcinoma risk
24842074 pharmacogenetic analysis shows that GSTM1 may have a role in survival after oxaliplatin therapy
24840051 GSTM1 gene polymorphism may be associated with risk of severe vaso-occlusive crises among Egyptian sickle cell disease patients.
24815471 the risk of cervical lesions might be significantly related to the GSTM1 null genotype, especially in women aged above 45 years. Furthermore, the GSTM1 polymorphism might have greater role in development of early stage lesions.
24809844 role of GSTT1 and GSTM1 polymorphism in COPD with special reference to peoples living in the vicinity of the open cast coal mine of Assam
24806557 Examined the role of gst polymorphisms and urinary metabolite levels after inhalation of propulsion fuel fumes. Data show significant gene-environment interaction effecting urinary metabolite concentrations after air naphthalene exposure.
24788870 GSTM1 null genotypes are associated with the risk of developing essential hypertension.
24754249 The present study suggested that GSTM1, GSTT1 and FTO gene polymorphisms are associated with increased risk for cataract in North Indian populations.
24740636 GSTM1 polymorphisms are associated with bladder cancer.
24732639 Polymorphisms in GSTT1 and GSTM1 are associated with the risk of lung cancer in a gender-specific manner.
24729086 Our study suggested that the GSTP1 A313G and GSTM1 null/present polymorphisms could predict the treatment response of the platinum-based chemotherapy in NSCLC patients, especially in East-Asian patients.
24716937 Positive associations between GST polymorphisms (GSTM1 and GSTT1 but not GSTP1) and acute leukemia risk.
24689813 This meta-analysis suggested that the GSTT1 and GSTM3 polymorphisms might influence osteosarcoma risk.
24685594 GSTM1-null and GSTT1-null genotypes were found to be independent risk factors for the development of sential arterial hypertension in Slovenian patients with type 2 diabetes.
24682953 Our study found that the GSTM1 null genotype appeared to be a significant risk factor for lung cancer in East Asia population
24671854 GSTM1 polymorphisms are associated with chronic myeloid leukemia.
24670356 Null GSTM1 genotype was not associated with susceptibility to COPD.
24659449 GSTT1 null genotype was associated with an increased risk of chronic myeloid leukemia, as were the double null GSTT1 and GSTM1 genotypes
24655088 demonstrate that acute exposure to relatively high concentrations of diesel exhaust produces cardiovascular changes in middle-aged GSTM1 null individuals
24643684 this meta-analysis demonstrates that the GSTM1 null gene polymorphism is an increased risk of laryngeal cancer in Asians and Caucasians.
24640692 the combination of allelic GSTM1 "+"/GSTT1 "+" variants was significantly higher in long livers compared to the control group
24637631 This study suggests that at least one deletion of the GSTM1 and GSTT1 genes represents a risk factor for anxious smokers.
24637014 Results show that double null genotype in GSTM1 is associated with antitubercular agent hepatotoxicity
24613990 increased BR was associated with gas for cooking among subjects with the null genotype for GSTM1 which may be an indication of the oxidant effects on the bronchi of exposure to nitrogen dioxide originating from cooking with gas.
24605635 Polymorphism of GSTM1 and GSTT1 genes is associated with development and severity of asthma in children.
24582550 no significant association between null mutation and advanced pelvic organ prolapse
24562622 Null genotypes for both GSTT1 and GSTM1 deletion polymorphisms also increased gastric cancer risk (OR 1.37, 95% CI 1.04-1.80, p = 0.03).
24559168 The significant detection of GSTT1 null genotype more in controls than in asthmatics with no association with other atopic manifestations or asthma severity and the lack of association detected between GSTM1 polymorphism in relation to asthma.
24535908 The presence of polymorphic forms of GSTP1, GSTM1, and GSTT1 was crucial to conferring better OS and DFS among women with negative axillary lymph nodes.
24535898 Polymorphisms in the GSTT1 and GSTM1 genes are associated with increased risk of preeclampsia in the Mexican mestizo population.
24535271 These findings suggest that polymorphisms of the MTHFR C677T, GSTM1 and GSTT1 genotypes do not contribute to the development of PTC susceptibility in the Korean population.
24532428 meta-analysis does not provide a strong evidence for causal associations between GSTM1 and GSTT1 polymorphisms and risk of ovarian cancer in Caucasians
24528063 Our results indicate no overall association between the GSTM1 and GSTT1 deletion polymorphisms and pancreatic cancer risk in the Japanese subjects in our study.
24528041 We discovered that GSTM1 deletion polymorphism had a significant effect on the susceptibility of oral cancer in the Indian population.
24527777 novel multiplex PCR method of GSTM1, GSTT1, and GSTP1 polymorphisms is simple, fast, low-cost, and reliable for the simultaneous detection of GSTM1, GSTT1, and GSTP1 Ile105Val polymorphisms.
24525147 this meta-analysis suggested that there is overall lack of association between GSTM1 genotypes and CHD risk, however, GSTM1 null genotype when combining with smoking history may contribute to CHD susceptibility.
24508281 Our results suggest that the GSTM1non-null, GSTT1null, and CYP1A1*2A genotypes may be good prognosis markers in patients with prostate cancer
24500512 Breast cancer patients presented higher frequency of homozygous deletion of the GSTM1 gene compared with the control group
24467372 The GSTM1-null genotype, NAT2 rapid acetylator phenotype influenced the sporadic CRC risk differently depending on the gender of the patient.
24460270 GSTM1 null genotypes are risk factors for lung cancer.
24423050 Combined GSTM1*0/GSTA1*A genotypes might be considered as genetic markers for cardiovascular death risk in ESRD patients, which may permit targeting of preventive and early intervention.
24407598 A multiplex polymerase chain reaction (PCR) method was used to detect the deletions in GSTM1 and GSTT1 genes in the genomic DNA in 346 atherosclerosis patients and 330 controls
24399650 demonstrated that the GSTM1 and GSTT1 null genotype may be associated with an increased risk of Hepatocellular carcinoma (HCC) and that individuals having the combination of both defective GST genotypes may be more susceptible to developing HCC
24391774 A meta-analysis provided strong evidence that the GSTM1 genotype is associated with cervical cancer development, and that smoking and HPV infection modified the association between the null GSTM1 genotype and cervical cancer.
24382428 The results of this meta-analysis suggest that GSTM1 polymorphism is weakly associated with the risk of Parkinson disease in Caucasians.
24381101 The frequency distribution for single, double and triple combinations of genotypes of GSTT1, GSTM1 and GSTP1 showed the varying degrees of association with Diabetes mellitus type 2
24375038 GSTM1 polymorphisms are not associated with gastric cancer in a small group of the Turkish population
24344877 High expression of GSTM1 is associated with chronic obstructive pulmonary disease.
24337975 summarized odds ratio for RCC of the GSTM1 null and GSTT1 null polymorphisms was 1.02 (95% confidence interval (CI) 0.91-1.15, P = 0.70) and 1.28 (95% CI 0.96-1.72, P = 0.09), respectively
24324590 GSTM1 gene expression correlates to leiomyoma volume regression in response to mifepristone treatment.
24319713 Association of GSTT1 and GSTM1 polymorphisms and chronic mercury intoxication.
24318990 Stratified analysis according to ethnicity showed that the GSTM1 null genotype was associated with increased risk of gastric cancer among Asians both in ever-smokers (OR = 1.841, 95% CI 1.184-2.861) and non-smokers (OR = 1.773, 95% CI 1.382-2.275)
24295891 GSTM1/T1 null polymorphisms may be associated with vitiligo
24291050 These results demonstrate significant associations between low activity GST genotypes and proatherogenic lipoprotein particles in hemodialysis patients which might further increase their cardiovascular disease risk.
24276031 Polymorphisms in GSTM1 gene is associated with secondary mixed phenotype acute leukemia.
24254297 There was no association between GSTM1 and GSTT1 genotypes and colorectal cancer risk
24250808 These findings indicate that GSTM1 and GSTT1 polymorphisms may play critical roles in the development of cancer, especially in smokers.
24244742 Data show that the GSTM1 null genotype is associated with an increased risk of gastric cancer among Asians but not among Caucasians.
24216264 organochlorine pesticides level in chronic kidney disease patients is partially dependent on GSTM1/GSTT1 polymorphism and particularly GSTM1(-)/GSTT1(-) genotype is more vulnerable in this regard
24203463 GSTT1, GSTM1 and GSTP1 gene polymorphisms were analysed in 321 type 2 diabetes mellitus patients and 309 healthy controls from an endogamous population from north India.
24197978 The findings from our meta-analysis suggest that GSTM1 null mutation is significantly associated with a risk of colorectal cancer in Chinese population.
24194954 GSTM1 null polymorphism is capable of causing childhood acute leukemia susceptibility.
24136740 GSTM1 null genotype is likely to be associated with risk of gallbladder cancer (Meta-Analysis)
24120392 The results suggest that null genotypes of GSTM1 and GSTT1 genes may contribute to the development of BPD in our Chinese Han population
24114827 Report GSTM1 null and combined GSTM1 and T1 null genotypes to be risk factors of anti-TB drug-induced hepatotoxicity in Western Indian population.
24098457 Although there was no association of GSTM1 deletion polymorphism with susceptibility to T2DM, the influence of this polymorphism on important clinical parameters related to glycemia and blood pressure levels was verified.
24086370 this is the first meta-analysis evaluating the relationship of polymorphisms and hypermethylation in GSTs and biochemical recurrence.
24084248 findings showed a significant association between the GSTM1 (deletion) and MGMT rs12917 (Phe/Phe) haplotype and the formation of DNA adducts in smokers; presence of these variants conferred a greater risk for higher adduct levels in this Mexican population
24075358 Data indicate that genotypes of the GSTA1, GSTM1, GSTT1, and GSTP1 did not contribute independently towards the risk of bladder cancer, but in association with smoking, both GSTA1 and GSTM1 increase individual susceptibility to bladder cancer.
24053064 The study indicates that GST T1 null genotype and GST T1 null/M1 wild combination could be considered a risk factor for type 1 diabetes development in Slovak children
24048194 the absence of GSTM1 activity can be compensated for by the overexpression of GSTM2.
24022663 the GSTM1 null variant is significantly associated with risk of bladder cancer in the Chinese Han population.
24022662 the GSTM1 null genotype is significantly associated with increased risk of childhood acute leukemia in Chinese.
24014086 there is an obvious association between the GSTM1 null genotype and risk of colorectal cancer in Asians.
24008019 Significant association has been found between GSTM1 polymorphism and type 2 diabetes mellitus. (Meta-analysis)
23982010 This study suggests the association between Parkinson disease and previous pesticide exposure, the effects of which seem to be enhanced when combined with the nullity for GSTT1/GSTM1.
23949201 Data indicate that genetic polymorphisms of aflatoxin B1 (AFB1) metabolic enzymes CYP2E1, EPHX1, GSTM1, and GSTT1 were not associated with gastric cancer, with the exception of CYP1A2.
23932298 study suggests the potential pathogenic role of GSTT1 deletion, and double deletion (GSTM1 null/GSTT1 null) on the MS susceptibility.
23900674 GSTM1 null gene polymorphism may be an increased risk of oral cancer in Asians but not in Caucasians.
23888321 the GSTM1 gene polymorphism contributes to PCa susceptibility, while GSTT1 gene polymorphism is not associated with PCa in our study.
23886197 GSTM1 polymorphisms are associated with acute myeloid leukemia.
23886179 High GSTM1 expression is associated with colorectal cancer.
23886141 Genetic deletions of GSTM1 is associated with head and neck cancer.
23884605 Studies shows that glutathione S-transferase M 1 (GSTM1) null genotype is not associated with ovarian cancer risk.
23877133 Our case-control study showed the GSTM1 null genotype was significantly associated with idiopathic oligozoospermia, while the null genotype of GSTT1 was significantly associated with normozoospermia and azoospermia.
23873097 No association of maternal GSTM1 (del) and GSTP1 (Ile105Val) genetic polymorphisms with Congenital malformations of the child was identified.
23845145 Active smoking and GSTM1-null genotype appear to be risk factors for thiopurine induced serious adverse effects (i.e. myelosuppression, hepatotoxicity and pancreatitis) in patients with Crohn's Disease
23810248 Data indicate that the GSTM1-null genotype plays an important role in genetic susceptibility to muscle invasive bladder cancer (MIBC) and the GSTT1-null genotype is associated with disease progression and shorter survival in MIBC.
23803127 study showed the GSTT1 null polymorphism to be associated with smoking-induced lung cancer and the GSTM1 null polymorphism to have a link with non-smoking related lung cancer
23801151 The GSTM1 null genotype is associated with increased risk of oral cancer in East Asians. [Meta-analysis]
23790786 Study found the null GSTM1 genotype as a risk factor for multiple colorectal synchronous cancers and for an association of synchronous colorectal with other cancers
23765968 A study of a Brazilian population with malignant glioma to determine whether GSTM1 and GSTT1 genetic polymorphisms influence the response to intranasal administration of perillyl alcohol and the survival rate, is reported.
23758905 Polymorphisms in GCLC, GSTM1, GSTT1, and GSTP1 genes associated with metabolism of glutathione act on cystic fibrosis severity.
23749488 GSTT1 and GSTM1 polymorphisms correlate with susceptibility to esophageal neoplasms in different Indian populations.
23747403 meta-analysis suggested that GSTM1 null genotypes are associated with increased primary open-angle glaucoma (POAG) risk in Asian populations but not Caucasian and mixed populations; dual null genotype of GSTM1/GSTT1 is associated with increased risk of POAG
23731957 GSTM1 was not associated with esophageal adenocarcinoma or esophageal squamous cell carcinoma susceptibility in Caucasians.
23725116 Deletion of GSTM1 gene is associated with the development of acute lymphocytic leukemia and acute myeloid leukemia.
23717494 The GSTM1, GSTT1 and GSTP1 polymorphisms are not associated with the development of RCC.
23707957 A meta-analysis to investigate polymorphisms in the CYP1A1 subfamily for leukemia risk showed that children who carry both the CYP1A1*2A variant and the glutathione S-transferase M1 null genotype have an increased risk of acute lymphoid leukemia.
23690164 Deletion of GSTM1 was associated with low urinary sodium excretion and modulated the interaction between sodium intake and blood pressure in Brazilian subjects
23684483 Data indicate that GSTM1 deletion may contribute toward myelodysplastic syndromes (MDS) progression.
23681307 The study indicated a potential role for GSTM1 polymorphism in predicting the clinical outcomes of treated oral carcinoma patients
23679259 GSTM1 null genotypes are associated with an increased risk of nasopharyngeal cancer.
23675469 High expression of GSTM1 and GSTM4, along with increased endogenous reduced glutathione levels, help to maintain a more reduced state of cytochrome c which decreases apoptosis thus contributing to methotrexate resistance in human MCF7 breast cancer cells.
23661361 GSTM1 deletion and dual deletions in GSTM1-GSTT1 loci are associated with brain tumor in males.
23661016 GSTM1 null genotype can modulate the risk for head and neck cancer.
23631429 These results indicated that the null genotype of the GSTM1 gene might contribute to the susceptibility of male infertility, whereas the null genotype of the GSTT1 gene may be a genetic susceptibility factor of male infertility for the Chinese.
23628324 Polymorphisms of GSTM1 were not associated with breast cancer risk in a case-control study of Lebanese women.
23625656 findings from this meta-analysis provide a strong evidence for the association between GSTM1 null genotype and risk of esophageal carcinoma in Chinese population, and GSTM1 null genotype contributes to increased risk of esophageal carcinoma in Chinese
23600494 This meta-analysis provides evidence that GSTM1 and GSTT1 polymorphisms may be risk factors for asthma.
23590899 The absence of GSTT1 and/or GSTM1 was an important risk factor for increasing the morbidity of SCA, especially in regard to acute chest syndrome.
23589999 GSTT1, GSTM1, and GSTP1 polymorphisms are not associated with endometrial cancer in the Caucasian population.
23570881 The GST genetic variants examined were not associated with susceptibility to coronary artery disease in our Taiwanese cohort.
23552977 the association of genetic polymorphisms in GSTM1, GSTT1, GSTP1, and those involved in DNA damage repair, OGG1 and XRCC1, in an Italian cohort of sporadic Parkinson's disease patients, was studied.
23537991 GSTM1 polymorphism is associated with an increased risk of rheumatoid arthritis in East Asians.
23534760 This meta-analysis of available data suggested that the GSTM1 null genotype does contribute to increased risk of prostate cancer in people who live in Asian countries.
23484121 in men with blood lead >6.47 mu g/dL the adjusted odds ratio (OR) of CRP levels for individuals with GSTP1 variants allele, GSTM1 null, GSTT1 null, double-null GSTM1, and GSTT1 compared with wild-type allele.
23481061 The findings of this preliminary study suggested an association between the variants of GSTM1 and toxicity observed due to cisplatin.
23469236 Strong association has been found between HPV infection, GSTM1-GSTT1 null genotypes, mtDNA content, and the development of oral squamous cell carcinoma.
23464442 GSTM1 null frequency did not deviate from most other Indian ethnic groups.
23450492 The M1(-/-) and P1(Ile/Val or Val/Val) genotype and the M1(-/-), T1(+/+) and P1 (Ile/Val or Val/Val) genotype are associated with reduced risk of azoospermia in ethnic Chinese Han population.
23444902 The association of glutathione S-transferase gene mutations (including GSTT1 and GSTM1) with the prognostic factors and relapse in acute lymphoblastic leukemia.
23444898 The oral cancer risk was significantly increased in the patients having either alone or concurrent deletion of GSTM1 and GSTT1
23437305 Our results indicate that both GSTM1 and GSTT1 null genotypes are associated with an increased HCC risk in Chinese population. Peoples with dual null genotypes of GSTM1-GSTT1 are more susceptible to developing HCC.
23433732 GSTT1 and GSTM1 polymorphisms are genetic risk factors for pregnancy loss in an Indian study population.
23395936 Occupationally exposed workers who carried null GSTM1 were more susceptible to damage from polycyclic aromatic hydrocarbons. [meta-analysis]
23394311 GSTM1 and GSTA1 polymorphisms significantly impact the malignant potential of transitional cell carcinoma of the urinary bladder.
23377313 meta-analysis provides evidence that there may be an increased risk of anti-tuberculosis drug-induced hepatotoxicity in individuals with null genotypes of GSTM1 in the total population, especially East Asians and patients receiving HRZE or HRZES
23376175 GSTM1 and GSTT1 were significantly linked with the risk of breast cancer in smokers and in Pakistani women with a history of breast cancer in the family
23368529 Meta-analyses of available data suggest a significant association between the GSTM1-null genotype and the risk of childhood asthma, and the GSTM1-null genotype contributes to increased risk of childhood asthma, especially in Caucasians and Africans.
23357602 GSTM1 polymorphism associated with testosterone level in filling station workers.
23342067 GSTM1 null polymorphism was not associated with a POAG risk, and this negative association maintained in Caucasian.
23330093 relationship between blood levels of HSP70 and HSP90 and genotypes of HSP70, GSTT1, and GSTM1 polymorphic variants in individuals chronically exposed to mercury; combination of GSTT1(+)/GSTM1(0/0) genotypes was associated with reduction of protein levels; variants including GSTT1(0/0) were associated with a significant elevation
23324581 Polymorphisms in GSTM1 gene is not associated with oligoasthenoteratozoospermia.
23317262 GSTM1 polymorphism is associated with nasopharyngeal cancer susceptibility.
23317232 The prevalence of homozygous null GSTM1 genotype is significantly higher in Caucasians and Asians as compared to Indian population.
23311983 Null genotypes of GSTM1 and GSTT1 are associated with spermatogenesis impairment and may contribute to spermatogenesis impairment and male infertility in the Chinese population.
23296494 Evidence from current meta-analysis suggests an association between GSTM1 null genotype and risk of type 2 diabetes.
23296061 null genotypes of GSTM1/GSTT1 and dual null genotype of GSTM1-GSTT1 are all associated with increased risk of diabetes mellitus, and null genotypes of GSTM1/GSTT1 and dual null genotype of GSTM1-GSTT1 are potential biomarkers of diabetes mellitus
23293967 Significant increase in urinary 8-OHdG levels in null GSTM1 genotypes.
23292236 GSTM1 null individuals older than 4 years had more frequently graft versus host disease (P=0.03).
23287989 Glutathione S-transferase M1-null genotype is associated with sinusoidal obstruction syndrome in oxaliplatin-treated patients with metastatic colorectal cancer.
23275251 GSTM1 polymorphism is associated with nasopharyngeal cancer.
23275234 Our results showed that individuals with the null genotypes for GSTM1 had protective effect
23268570 The findings suggested a birthweight reduction among light-smoking mothers with the GSTM1-null genotype. When combined with GSTT1-null genotype, the birthweight reduction was significant in light-smoking mothers.
23265943 A significant association was found between the numbers of D-loop mutation and GSTM1, GSTT1 null genotypes respectively in oral squamous cell carcinoma
23244102 GSTM1 gene polymorphism is associated with response to therapy in breast cancer.
23239128 GSTM1 null genotype contributes to male infertility susceptibility.
23238917 GSTM1 null genotype contributes to increased risk of male idiopathic infertility in Caucasians, and males with dual null genotype of GSTM1/GSTT1 are particularly susceptible to developing idiopathic infertility.
23232001 GSTM1 null genotype may be associated with an increased risk of ATDILI
23227845 GSTM1 and GSTP1, but not GSTT1 genetic polymorphisms are associated with increased risk of breast cancer in our population
23222181 The largest associations for low birth weight risk were found for third trimester among total trihalomethanes and chloroform-exposed women with the GSTM1-0 genotype. The effect on small for gestational age was not statistically significant.
23220723 It was conclude that GSTM1 is normally upregulated in chronic kidney disease in a protective response to increased oxidative stress.
23215883 Our results show that GST-M1 and GST-T1 homozygous deletions have opposite correlation with relapse, the former being protective and the latter unfavourable in specific subsets of acute lymphoblastic leukemia patients.
23204253 The wild-type GSTM1 genotype augments allergen-induced neutrophilic airway inflammation in humans with atopic asthma in vivo.
23189206 people with GSTM1 null genotype, with dual null genotype of GSTM1 and GSTT1, or with GSTT1 null genotype and GSTP1 A131G polymorphism are associated with high risks of PCa.
23185284 This meta-analysis suggests that the GSTM1 and GSTT1 null genotype may slightly increase the risk of hepatocellular carcinoma.
23184765 GSTM1 null polymorphism is not associated with risks of pancreatic cancer.
23184764 GSTM1 null polymorphism is not associated with risks of basal and squamous cell carcinomas.
23175321 Smoking was inversely associated with speed of sound (SOS) and bone quality index (BQI) among subjects with GSTM1 null genotype.
23173169 genetic association studies in a population in South Korea: Data suggest that genetic polymorphism in GSTM1 (i.e., gene deletion) could be a determinant in whether maternal dietary iron during pregnancy influences birth weight and oxidative stress.
23167410 Polymorphisms of GSTM1 and GSTT1 genes were not found to be directly associated with stomach cancer in Mizoram. However, they appeared to be effect modifiers.
23164539 There was evidence that the null of GSTM1 and GSTM1-GSTM1 increased the risk of male factor infertility, but the null genotype of GSTT1 was not associated with an increased infertility risk.
23159782 The effect of cigarette smoke and arsenic exposure on urothelial carcinoma risk is modified by glutathione S-transferase M1 gene null genotype
23159492 results suggest higher levels of 1,3-Butadiene (BD) exposure in the workplace resulted in increased chromosomal damage, and that polymorphisms in GSTT1 and GSTM1 genes might modulate the genotoxic effects of BD exposure; the GSTT1 and GSTM1 polymorphisms exhibited an additive effect
23152866 The combined genotypes of CYP1A1 and GSTs can help to identify vulnerable pregnant women who are subject to high risk of spontaneous preterm delivery due to passive smoking.
23146971 We did not find significant associations for GSTT1 and GSTM1 genotypes and prostate cancer biochemical relapse after prostatectomy
23142420 there is a hierarchy of effectiveness for polymorphic variants of GSTP1-1 to regulate Prdx6 peroxidase function, a feature that may influence human population susceptibilities to oxidant stress.
23107768 the combination of the GSTM1 and GSTT1 null genotypes showed a non-significant trend to an increased risk of schizophrenia.
23090633 results of this meta-analysis showed that there was interaction between smoking and GSTM1 genotype in the development of lung cancer in the Chinese
23079819 This study aimed to detect the GSTM1 gene polymorphism in patients with primary open-angle glaucoma.
23077643 this meta-analysis presented additional evidence of the association between GSTM1 and GSTT1 polymorphisms and head and neck squamous cell carcinoma risk
23077626 Therefore, GSTM1*0 may be possible protection factors for leprosy patients.
23073505 The GSTM1 null genotype has an unfavorable influence on the long-term allograft outcome of renal transplant recipients.
23071687 GSTM1 null allele was a low-penetrant risk factor for prostate cancer among Asians.
23053970 GSTM1 and GSTP1 polymorphisms are not associated with the risk of rheumatoid arthritis.
23026209 subgroup analysis on ethnicity showed no notable association between the polymorphism and the risk of idiopathic male infertility in any of GSTM1 null and GSTT1 null genotype
23021798 GST T1 wild allele and GST T1/M1 wild/null genotype can be considered as risk factors for cardiovascular autonomic neuropathy in Slovak adolescents with T1 diabetes.
23019974 The difference between the frequency of homozygous deletion of GSTM1 in smokers is insignificant in the early stages of chronic obstructive pulmonary disease.
23014993 GSTM1 and GSTT1 genotypes might be involved in the pathogenesis of type II diabetes mellitus in south Iranian population.
23013535 Results suggest that genetic polymorphisms in the CYP1A1, GSTM1, GSTT1 and GSTP1 metabolic genes were not significantly associated with lung cancer risk.
23011367 The allelic mutation of the GSTM1 gene is a predisposing factor for the development of Sensorineural Hearing Loss.
23000285 the GSTM1 polymorphism plays a role in the development of lung cancer and modifies the risk for smoking-related lung cancer in a Chinese population.
22994755 GSTM1 null genotypes are associated with increased risk of gastric cancer, and smoking modifies the association.
22994718 GSTM1 null genotype was not associated with risk of RCC overall.
22972496 The cumulative meta-analyses showed a trend of more obvious association between GSTM1 null genotype and increased risk of laryngeal cancer.
22960333 GSTM1 polymorphisms associate with epithelial ovarian cancer risk.
22952149 The GSTM1, GSTT1, and GSTP1 gene polymorphisms evaluated in this study are not relevant when determining the individual susceptibility to GC or phenotype in a South-European population.
22924777 DNA methylation analysis of ALOX12 and GSTM1 in acute myeloid leukaemia identifies prognostically significant groups.
22921799 In title.
22903474 These results demonstrated that amongst populations studied to date, GSTM1 and GSTT1 null genotypes are associated with strong and modest increase in the risk of male infertility, respectively.
22900055 This meta-analysis supported that the GSTM1 gene polymorphism was associated with laryngeal cancer.
22893352 Report possible associations between GSTM1 gene polymorphism and the risk of lung cancer.
22885711 Investigate whether the genetic polymorphisma GSTP1, GSTM1, GSTT1 are associated with susceptibility to noise-induced hearing loss. Results suggest that GSTM1, but not GSTT1 or GSTP1 is associated with susceptibility to noise-induced hearing loss
22880812 the dual null genotype of GSTM1-GSTT1 is associated with RCC risk in Asians [meta-analysis]
22876127 The polymorphisms of GSTM1 and GSTO2 along with the work place influence may act additively for developing cataract.
22874804 GSTM1 NULL and NULL/NULL genotype increases the risk for schizophrenia in an Iranian population.
22867088 GSTM1 regulates DEP-induced IL-8 and IL-1beta expression in primary human bronchial epithelial cells by modulation of ROS, ERK and Akt signaling.
22858312 polymorphic deletions of glutathione S-transferases M1 might be a genetic risk factor for myocardial infarction in patients with type 2 diabetes mellitus
22852846 These data suggest that GST polymorphisms may be associated with methylmercury detoxification.
22845549 GSTM1 and GSTT1 null genotypes do not seem to play important roles in anti-tuberculosis drug-induced liver injury in Brazilians; GSTM1 polymorphisms were possibly related to the intensity of toxicity
22841242 Risk of rejection was higher for subjects with the GSTM1 null genotype and suggest a role for GSTM1 genotype in cyclosporine A detoxification and drug nephrotoxicity.
22817656 Genome-wide copy number variants analysis replicates the association between GSTM1 deletion and bladder cancer
22813660 No association is found with GSTM1 null genotype (34% null in Alzheimer's disease compared with 31% null in controls).
22812193 no association between gene polymorphisms and asthma in adult patients from Rome, central Italy
22809837 data showed that BPDE-DNA adduct levels were positively correlated with gender, smoking status, betel nut chewing, alcohol consumption. Difference in DNA adduct levels could be explained by genetic polymorphisms of glutathione S-transferase M1 (GSTM1).
22799358 This study reported the carriage of null GSTT1 and null GSTM1 might be linked to the higher death risk from gastric cancer in Chinese population.
22788240 Polymorphisms in the NAT2, GSTM1, GSTT1, and CYP2E1 genes were found to have an increased risk of adverse drug reactions , as revealed by gene-gene interaction analysis.
22782580 There were no significant differences in CYP1A1-MspI SNP and GSTM1 genotype frequencies in this family when compared to data for Brazilian populations.
22782090 There was a statistically significant association between the combined GSTM1 and GSTT1 null genotypes (M-/T-) and mammographic density in post menopausal women
22766250 Several manifestations of Behcet's disease may be influenced by smoking, and this effect can be augmented in patients carrying GST gene polymorphisms.
22752755 CYP1A1 m1 and m2 genotypes singly act as protective factors but in the absence of GSTM1 and/or GSTT1 gene significantly alters risk towards oral submucous fibrosis.
22748443 Our findings support the association of genotypes GSTM1 0/0 and GSTP1 A105/A105 and smoking with CAD.
22736250 No role was found for GSTM1 and GSTT1 polymorphisms in oxidative stress induced in the workers of natural gas refineries.
22734843 the GSTT1 null genotype appears to be associated with a modest increase in the risk of NHL, whereas the GSTM1 and GSTP1 Ile105Val polymorphisms are unrelated to lymphoma risk.
22732554 The study evaluated associations between air pollutants and markers of insulin resistance (IR), and effect modification by glutathione S-tranferase mu 1, theta 1, and p1 genotypes (GSTM1, GSTT1, and GSTP1) in a Korean elderly environmental panel study.
22697302 Variability in GST genes (GSTA1, GSTT1, GSTP1, GSTA1) is not a major determinant of colorectal cancer susceptibility in the Central European population.
22692893 Double deletion of GSTM1 and glutathione S-transferase theta;-1 (GSTT1) significantly increases benign prostatic hyperplasia risk.
22686321 The normal distribution of the GSTM1 negative genotype in patients with indication for hip or knee replacement indicates that the role GSTM1 in these patients is different from that in other aseptic inflammatory diseases
22686319 severely occupationally exposed Caucasian hard coal miners do not present an elevated level of GSTM1 negative individuals
22686318 The frequency of rapid GSTM1 genotype was 53% in colon cancer cases, 46% in rectal cancer cases, and 47% in controls
22683820 The role played by GSTM1 in lung inflammation. [Review]
22681588 Analysis of the combined effect of GSTM1 and GSTT1 polymorphism (using GSTM1+/GSTT1+ as reference) found a significant association of vitiligo risk with the GSTT1/GSTM1 double-null type only.
22676722 Results show GSTM1 insertion allele was associated with prematurity protection
22665971 The GSTM1 positive genotype and a combination of GSTM1 positive and GSTT1 null genotypes may be associated with a susceptibility to age-related cortical cataract in the Han Chinese population.
22664944 The CYP1A1*2A (T/C, C/C), mEPHX*3 (His/His), GSTM1 (null), GSTT1 (null) and XRCC1 399 (Arg/Gln, Gln/Gln) alleles correlate with an increased predisposition to ulcerative colitis.
22660220 GSTM1 null showed no significant association with oral scc
22653598 It was concluded that early ageing is under the influence of GSTM1 and GSTT1 and the environmental and socio-demographic factors.
22652274 the combined evaluation of GSTM1-GSTT1-GSTP1 and OGG1 Ser326Cys gene polymorphisms can be used as candidate genes in the etiology of T2DM, especially in the development of T2DM.
22642106 the alleles of MTHFR and GSTM1 genes may modulate the risk of glucocorticoid-induced (GI)osteoporosis in patients with bronchial asthma.
22631654 meta-analysis provided strong evidence that the GSTM1 genotype is associated with the development of cervical cancer, especially in smokers, and Chinese and Indian populations; no association was found for GSTT1 null genotype carriers
22622525 GSTM1 null genotype contributes to increased risk of male infertility.
22614024 GSTM1 null and CYP2A6*9 showed significant associations with cytokinesis-blocked micronuclei assay results in lymphocytes of tobacco farmers
22611936 The genetic polymorphisms of CYP1A1-exon7, GSTM1, XRCC1-194 and XRCC1-280 might contribute to the risk of developing lung cancer in Henan population.
22576927 significant association with risk of developing CML was found for MTHFR 1298AA and GSTM1 non-null genotypes
22575983 The evidence suggests that GSTM1 null genotype is associated with the development of cervical cancer especially in Chinese and Indian women.
22570144 There was a significantly increased risk of birth defects in GSTM1 not-null cord-blood genotype in pregnancies exposed to solvents.
22539183 In comparison with European and Asian populations, Afghanistan populations like Iranian populations showed intermediate frequency for the GSTM1 null genotype.
22537952 GSTT1 and GSTM1 might play a potential role in the pathogenesis of both infectious mononucleosis and acute lymphocytic leukemia.
22528457 No differences are observed in GSTM1 and GSTP1 genotype distributions between cases and controls in patients with stroke and hypertension.
22502716 Polymorphic variation in GSTM1 gene was associated with chronic myeloid leukaemia.
22502694 Polymorphic variation in GSTM1 gene was not associated with brain tumor.
22502660 Polymorphic variation in GSTM1 gene was not associated with gliomas.
22484853 Data indicate that GSTT1 null genotype conferred almost fourfold increased risk of diffuse large B-cell lymphoma (DLBCL), while GSTM1 null genotype was not associated with DLBCL risk.
22484660 It was shown genetic polymorphisms as a result of deletions in the GSTT1 and GSTM1 genes confer an increased risk towards asthma.
22471491 Polymorphisms in GSTM1 gene is associated with gastric cancer.
22471480 Polymorphisms in GSTM1 gene is associated with osteosarcoma.
22446016 The data suggests that GSTM1 positive, GSTT1 null and double null (GSTM1 null and GSTT1 null) genotypes may confer risk for the development of age related cataracts.
22424617 A gene-environment interaction was observed for GSTP1(Ile/Ile) and GSTM1 null genotypes, modulating the effect of polychlorinated biphenyls on endometriosis risk.
22410570 The evidence presented suggests that GSTM1 and GSTM5 undergo epigenetic repression in AMD RPE/choroid, which may increase susceptibility to oxidative stress in AMD retinas.
22407040 When the patients were stratified by clinical and epidemiological features, the frequencies of the GSTM1 and GSTT1 null genotypes were similar, suggesting that the inherited absence of these enzymatic pathways does not alter the course of CF.
22393996 Our study provides evidence that genetic deletion of GSTM1 and GSTT1 may contribute to increased susceptibility to NPC in Chinese population, while GSTP1 may not.
22392686 decreased activity of GSTM1/GSTT1 enzymes elevates lung cancer risk in male smokers, likely due to impaired carcinogens detoxification
22383780 genetic association studies in a population of men in north India: Data suggest that risk of male infertility is lowered by the combined effects of the null genotypes of GSTM1 (glutathione S-transferase M1) and GSTT1 (glutathione S-transferase T1).
22381228 The GSTM1 null genotype is a risk factor for Alzheimer's disease in Italian patients.
22377702 Individuals homozygous for the deletion of GSTT1 are at a 2-fold-greater risk of diabetic retinopathy (DR), whereas the GSTM1 deficiency is associated with lower frequency of DR in type 2 diabetics.
22335459 There was no statistically significant association between GSTM1/GSTT1 null genotypes and ATDH.
22330623 Did not find significant association between the GSTM1 polymorphisms and carotid atherosclerosis in type 2 diabetics.
22327174 GSTM1 gene polymorhism a risk marker for the development of osteoporosis in aging population.
22312901 Enhanced predisposition to community-acquired pneumonia was shown to be characteristic of carriers of normal alleles of the GSTM1 locus (OR = 1.7; p = 0.010)
22311486 CYP1A1 mutant genotype and GSTM1 null genotype with smoke has increased the risk of lung cancer, with OR being 2.406(1.321-4.382), 2.755(1.470-5.163), respectively.
22310945 We observed a significant interaction between beta-hexachlorocyclohexane (b-HCH) and GSTM1- genotype and reduction in birth weight.
22296360 The pooled OR was 1.22 (95% CI 1.03 1.43) for the GSTM1 polymorphism while for GSTT1 polymorphism.
22248273 Genetic polymorphisms of GSTM1 is associated with lung adenocarcinoma.
22237425 This meta-analysis suggests that the null genotypes of GSTM1 and GSTT1 and the dual null genotype of GSTM1/GSTT1 were all not risk factors in colorectal cancer in Chinese population.
22234881 Copy number variations of GSTM1 is not associated with colorectal cancer risk or for an effective modification of cigarette smoking and menopausal hormone therapy.
22228263 Neither GSTM1 nor GSTP1 genotypes alone were significantly associated with FEV(1) intraday variability in South African children exposed to air pollutants
22228187 GSTM1 single nucleotide polymorphism is not associated with colorectal cancer.
22225519 GST genotypes GSTM1, GSTT1 and GSTP1 (including SNPs) seem to have no relevant association with PLE
22215096 combined gene dose of GSTM1 and GSTT1 may influence outcome in childhood acute lymphoblastic leukemia.
22213390 GSTM1 and XPD variant alleles, independently as well as in combination may serve as important predictors of clinical outcome in radiotherapy-treated oral squamous cell carcinoma patients.
22207177 The role of GSTM1, GSTT1, GSTP1 exon 5 and exon 6 polymorphisms on developing lung cancer, was investigated.
22184992 GSTM1 gene mutation is noted for the earlier onset (up to 5 years), severity, and poor prognosis of allergic dermatoses.
22183307 Endogenous DNA damage levels were analyzed in relation to polymorphisms in genes encoding phase I detoxifying enzyme-CYP1A1, phase II detoxifying enzymes-GSTM1, GSTT1, GSTP1 and enzyme involved in nucleotide excision repair-XPD.
22169897 frequencies of GSTM1 positive genotype were significantly higher in squamous cell carcinomas than those in controls; polymorphism of GSTM1 locus could be an important factor in susceptibility to squamous cell carcinoma among Japanese population
22160572 The GSTM1/GSTT1 null genotype is a significant risk factor for developing chronic obstructive pulmonary disease in Asian smokers.
22154357 Data suggest that the GSTP1 polymorphism and its combination with GSTM1, and GSTT1 may be associated with bladder cancer susceptibility in the Iranian population.
22146408 GSTM1*0 and GSTT1*0 appear to be risk factors for acute lymphoblastic leukemia, and "rapid or intermediate NAT2 genotypes" are associated with an elevated risk for acute myeloid leukemia
22139978 Presence of Helicobacter pylori infection along with GSTM1*0 was associated with lower enzyme activity in patient with gastric cancer.
22126558 The present case control study suggests no association of GSTM1 and GSTT1 gene deletions with sporadic form of breast cancer in Pakistani population.
22126490 Our findings suggest that the GSTM1 null genotype may contribute to colorectal cancer development in people over 60 years old.
22116675 GSTM1 polymorphisms did not influence the development of aristolochic acid nephropathy.
22109568 Our findings support the hypothesis that a polymorphism in GSTM1 is associated with lung cancer susceptibility.
22058002 These results give evidence that the GSTT1- and GSTM1-null genotypes, alone or combined, are associated with increased risk of type-2 diabetes mellitus, regardless of smoking status.
22054067 genetic variability in members of the GST gene family may be associated with an increased susceptibility to renal cell carcinoma and its progression
22048273 Combined analysis of both genes revealed that 14.4 percent of Bahrainis, 16.3 percent of Lebanese and 21.0 percent of Tunisians harbor the deleted genotype of both the GSTM1 and GSTT1 genes
22048269 a significant association of combination of GSTT1 gene presence and homozygous absence of GSTM1 gene with bone mineral density was demonstrated
22018952 Data suggests that GSTM1 null genotype alone and in combination with CYP1A1 m1 genotype may be predisposing risk factors for PV in the Jordanian population.
22017422 In the single SNP analysis, GSTM1 null type and AhRR variant type were associated with a significantly increased risk of endometriosis.
22012226 no significant associations were found between the homozygous GSTM1 null polymorphism and hepatotoxicity
22011249 Genetic polymorphisms of glutathione-S-transferase genes of GSTM1 is associated with nonalcoholic fatty liver disease.
21997310 Neonates with the GSTM1 null genotype are at high risk to develop pathologic hyperbilirubinemia and may have higher bilirubin levels.
21993019 This study demonistrated that gstm1 no association with Indian Parkinson's disease patients.
21969307 In Turkish CML patients, the GSTM1(+) /GSTT1(-) genotype was associated with a 2.5-fold increased risk compared with the GSTM1(-)/GSTT1(+) genotype, the second most frequent genotype, suggesting a complex interaction between GSTM1 and GSTT1.
21967523 Data shows that although this gene was not associated with PUVA outcome it was associated with clearance of Psoriasis in this group of patients.
21962942 genetic associations: GSTM1 null polymorphism is associated with increased risk of low-grade intraepithelial cervical lesions, but no increased risk of high-grade intraepithelial cervical lesions or invasive cervical cancer [Meta-Analysis/REVIEW]
21928235 GST M1 (+) genotype is associated with better survival in elderly peritoneal dialysis patients, who may have heavy oxidative stress as a result of the aging and PD processes.
21916526 A small cohort of Hodkin's patients with an international prognostic score >3 and undeleted GSTT1 and/or GSTM1, treated with ABVD had worse progression-free survival.
21912475 GSTM1/GSTT1 null genotypes are associated with increased risk of hepatocellular carcinoma in Chinese population [meta-analysis]
21896242 genetic association studies in Chinese population: Data suggest that blood biomarkers of oxidative stress are associated with combined influences of GSTM1/GSTT1 genotype and fruit/vegetable consumption.
21890078 paternal smoking and exposure to toxicants for both parents affect the risk of children with CHD. Polymorphisms in GST genes can modify a person's risk of toxicant exposure-induced disease.
21875259 Logistic regression yielding odd ratios resulted in no significant association between dietary isothiocyanates intake, GSTM1, GSTT1 or GSTP1 genotypes with oral cancer risk overall.
21870186 Data show that inherited combined CYP1A1 A4889G and T6235C abnormalities and GSTM1 and GSTT1 pathways are important determinants of HNSCC.
21868558 study demonstrated the role of both GSTM1 and T1 null genotypes in the development of high-grade cervical dysplasia in a Caucasian population
21859547 The combined effects of CYP1A1 gene and GSTM1 gene polymorphism are significantly associated with an increased risk to lung cancer.
21848428 CYP1A1 and GSTM1 polymorphisms should be considered as important parameters for the prediction of coronary artery disease.
21843791 Data suggest a significant association between polymorphism of glutathione-S transferase T1/M1 genotypes and cytogenetic biomarkers which are considered early effects of genotoxic carcinogens.
21839153 GSTM1 and GSTT1 status may not influence the risk of developing gastric cancer.
21813807 The concentration of serum vitamin C was higher in persons with the inactive GSTM1-0 genotype (P = 0.006).
21809368 VEGF and GST genotypes can combine to influence the risk for multiple myeloma in south-eastern Brazil. We hypothesize that the increased risk for disease related to the wild-type VEGF C936T and GSTM1 genotypes and the variant GSTT1 genotype.
21803734 Genetic polymorphism in GSTM1 is associated with colorectal cancer.
21786748 Data suggest that glutathione S-transferase M1, T1, and P1 genetic polymorphisms might affect hearing threshold levels for high frequencies only when workers are exposed to high noise levels.
21775774 An association between male infertility and the GSTM1 and GSTT1 null deletion was observed, but not with the CYP1A1 polymorphism in North Iranian men with idiopathic infertility.
21743873 No correlation between GSTM1 polymorphism and chronic rhinosinusitis with and without nasal polyps, allergies, or asthma was observed.
21738397 GSTM1 null polymorphism is associated with primary open angle glaucoma in the Brazilian population.
21736951 result suggests that the null deletion of GSTM1 and homozygote wild GSTP1 genotype can modulate DNA damage through gene-environmental interactions in workers occupationally exposed to some organophosphate pesticides
21734345 Combined EPHX1, GSTP1, GSTM1, and GSTT1 genetic polymorphisms may play a signi fi cant role in the development of pulmonary emphysema.
21728793 Association between the GSTM1 null genotype and hypertension was significant in younger subjects. Tobacco users with the GSTT1 null genotype were at an increased risk
21709011 CYP1A1 Ile/Ile genotype with GSTM1 null genotype combination may contribute to the development of bladder cancer in this Turkish population.
21701824 the protein encoded by the GSTM1 gene might have a protective function against oxidative stress in retina
21694442 Significantly higher malondialdehyde levels in GSTM1-/GSTT1- compared to GSTM1+/GSTT1+ in both benign prostate hyperplasia and prostate cancer groups indicate higher oxidative stress in individuals with double deletions.
21681823 No significant association was observed between GST genotypes and disease risk in relation to smoking or occupational exposure.
21651749 GST copy number variations were not significantly associated with respiratory outcomes and did not modify the effects of self-reported exposure to indoor sources of particulate matter on respiratory outcomes.
21629772 Findings indicate that GSTM1 and GSTT1 polymorphisms, particularly GSTM1-GSTT1 interaction, may play critical roles in the development of cervical neoplasia.
21619788 Urinary 1-hydroxypyrene concentrations can be modified by GSTM1, GSTT1 and GSTP1 gene polymorphisms.
21615938 The GSTM1 and DRD4 genetic polymorphisms are related to temporomandibular disorder.
21615880 results shed more light on the links between GSTM1/T1 genetics, oxidative stress, and vitiligo
21604464 The polymorphisms of GSTT1 and GSTM1 may affect the carcinogenesis of laryngeal carcinoma in the Han people in the Guangdong zone.
21586620 Our data indicate that common genetic variations in GSTM1, GSTT1, and GPX1 were not associated with bladder cancer risk.
21563941 Absence of association between GSTM1 and GSTT1 polymorphisms and melanoma susceptibility was found by meta-analysis.
21561808 Polymorphisms within Pon1, Pon2, and GSTM1 are associated with male infertility.
21559761 GSTM1 and GSTT1 null genotype alone, both combined or combined with GSTP1 valine alleles, are associated with higher susceptibility to breast cancer development
21558497 Our assessment of gene-environment interactions suggested GSTM1 and GSTT1 are not involved in the in vivo human metabolism of estrogen and its metabolites
21558090 This meta-analysis suggested that GSTM1 null status is associated with a high increase in the risk of bladder cancer.
21557334 Flavonols and flavanols (EGC in particular) were associated with a reduced risk of breast cancer among those null for GSTM1 and GSTT1, with a P-value of 0.04 for the interaction between EGC and GSTM1 polymorphism
21553222 Meta-analysis indicates that GSTM1 null genotype might be associated with increased gastric cancer risk in Asians.
21546615 Results suggest that the GSTM1 and GSTT1 null genotypes may predispose sperm to increased oxidative damage in infertile men with varicoceles.
21545219 GSTM1 deletion polymorphism is associated with oral cancer progression.
21545198 GSTM1 downregulation is associated with head and neck cancer progression.
21543101 gstm1 is associated with a higher incidence of sister chromatid exchange, high frequency cell, and cytokinesis blocked micronuclei
21520994 The null genotype of GSTM1 and the dual null genotypes of GSTM1/GSTT1 were risk factors in cervical cancer, and the null genotype of GSTT1 was not associated with cervical cancer risk.
21513434 Results suggest that Glutathione-S-transferase M1 null polymorphism is associated with susceptibility to chronic obstructive pulmonary disease, and an association was found between this polymorphism and pulmonary function in smokers and nonsmokers.
21508403 GSTM1 null genotype is associated with gastric pre-malignant conditions.
21499713 a reduction in the frequency of GSTM1-null genotypes might be involved in the pathogenesis of coronary artery disease in an Iranian population
21488930 Although the GST-M1 null genotype was higher in Grade 3 than in Grade 1, 2 and controls, there were no statistical differences between control group and varicocele groups according to GST-M1 and GST-T1 null genotype.
21474334 This meta-analysis result indicates that the GSTM1 null genotype is a low-penetrant risk factor for gastric cancer development in Asians.
21461548 Results suggest that subjects carrying both GSTM1 and GSTT1 null polymorphisms and experiencing sunburns in childhood have an extremely high risk of melanoma.
21458313 No relationship between GSTT1 and GSTM1 genotypes and renal cell carcinoma risk was observed
21445357 data provide support for the notion that variations in copy numbers of GSTM1 may influence risk in certain subsets of RA, but do not support a role for GSTM1 CNV as a factor that more generally modifies the influence of smoking on RA
21441173 data support the hypothesis that the GSTM1 null genotype is a risk factor for increased acute respiratory and systemic inflammatory response to inhaled clinical center reference endotoxin
21436184 Case-only analysis of 6 studies (552 cases) showed an inverse multiplicative interaction between GSTM1 null polymorphisms and smoking
21431478 The response rates to breast cancer chemotherapy were better, although not significantly so, in patients with the GSTM1 and GSTT1 null genotypes (odds ratio [OR] 2.06 and 1.45).
21389716 no correlation between genotype and myocardial infarction risk in smokers
21385088 GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese
21359474 results suggest a possible interaction between meat intake and GSTM1/GSTT1 polymorphisms in modulating the risk of head and neck cancer, influenced by vegetable consumption.
21358205 GSTM1 polymorphism is associated with oral submucous fibrosis.
21352813 GSTM1, GSTT1 and GSTP1 variants might contribute to the development of T2DM and GSTT1 variant alone is involved in the development of T2DM associated coronary artery disease complications in the South Indian population.
21349909 analysis of glutathione S-transferase copy number variation alters lung gene expression
21309732 combined genetic polymorphisms of GSTM1, GSTT1, GSTP1, and EPHX1 may have favorable effects on redox balance in chronic obstructive pulmonary disease patients.
21301992 The prevalence of the GSTM1(null)genotype in the normal Han population (Hubei, China) are 70.74% in UC patients which is a statistically significant increase.
21299892 GSTM1 was found to have bimodal expression in human skeletal muscle tissue.
21292509 Data indicate there were no statistical changes in the genotype distribution of GSTM1, MDR1 C3435T, and VEGF A2578C gene polymorphisms were observed between cases and controls.
21286014 Data reveal differences in time to tumor recurrence based on GSTM1 tissue genotype in non-muscle invasive bladder cancer (NMIBC)and identify GSTM1 as a prognosticator for determining recurrence in NMIBC.
21272319 GSTM1-genotype modulates the physiological response to cruciferous vegetable intake.
21254556 Cytochrome P4501A1, glutathione S-transferase M1 and T1 gene polymorphisms in chronic myeloid leukemia
21243434 GSTT1-null is associated with IBD, while GSTM1-null is conversely associated with inflammatory bowel disease. No association was found between GSTT1- null or GSTM1-null and specific inflammatory bowel disease phenotypes.
21243008 The results obtained demonstrated that simultaneous presence of three potentially risk alleles (GSTM1 null, GSTT1 null and GSTP1 Val) lead to a significant OR increase for prostate cancer.
21234761 We evaluated the influence of common polymorphisms of XRCC1, GSTP1, GSTT1, and GSTM on the individual susceptibility to CpG island hypermethylation in the non-neoplastic rectal mucosa in ulcerative colitis patients
21228718 the GST theta;1-null genotype and the 139A--G mEh gene polymorphism may enhance the susceptibility to acquired aplastic anemia
21212706 Our findings suggest that genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1 and GSTP1 may have a role in the development of (AMD) age-related macular degeneration.
21211368 The combination of GSTM1 null genotype and cooking oil fumes significantly increased the risk of female lung cancer.
21196426 Absence of one or both alleles for the GSTM1 gene did not influence airway function acutely
21176850 Data show There was no difference in polymorphic variants of GSTM1, NQO1-C609T and XRCC3-C241T between the patients and controls.
21176116 GSTM1 is associated with Atopic dermatitis susceptibility in Korean subjects.
21169033 Data show that GSTM1 wildtype had no effect on mortality in the low IL-6 group, but it was associated with a significant lower mortality rate in the high IL-6 level.
21167396 meta-analysis demonstrated that the GSTM1 gene polymorphism might be a risk factor for gastric cancer (GC) among Asians; smoking, Helicobacter pylori infection status did not modify the association between GSTM1 null genotype and GC risk
21158083 GSTM1 polymorphisms had no effect on susceptibility to hypoxia.
21152927 genetic association studies in Slovakian workers exposed to oxidants/oxidative stress: Subjects missing GSTM1 and GSTT1 due to gene deletions have lower levels of vitamin C in plasma.
21151336 There is a significant involvement of the GSTT1 and GSTM1 polymorphisms in female Pakistani patients having pseudoexfoliative glaucoma.
21150818 The GSTM1 null genotype confers additional risk for cervical cancer in non-Chinese populations.
21133626 GSTM1 deletion is significantly associated with the increased risk of symptomatic BPH, but none of the glutathion S-transferase polymorphisms appears associated with response to standard BPH therapy.
21133595 These results suggest that the GSTM1 and GSTT1 null genotypes are risk factors for head and neck cancer development among the Pakistani population.
21111108 GSTM1 genotype showed a risk for preterm delivery in Korean women.
21093063 This study found that the combination of the absence of GSTM1 gene and the of the GSTM1 gene with the polymorphism GSTA1*B/*B represents a risk factor for schizophrenia.
21089003 we investigated whether CAG repeat length in androgen receptor gene and GSTM1 and GSTT1 polymorphisms influence prostate cancer risk in Iranian newly diagnosed cancer patients
21089003 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
21087494 This study is the first to show that the GSTM1-null genotype exerts significant additive interaction with HLA-DRB1 shared epitope on the risk of ACPA positivity in rheumatoid arthritis
21087494 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
21086258 null genotypes of GSTM1 and GSTT1 genes were predominant in patients with nodules, indicating that individuals that possess these genotypes have a predisposition for thyroid disease
21086258 Observational study of gene-disease association. (HuGE Navigator)
21082260 The GSTM1 null genotype is associated with a modest increase in the risk of bladder cancer.
21082260 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
21079384 Observational study of gene-disease association. (HuGE Navigator)
21079113 No significantly increased risk of surgical complications was noted in patients with the null genotypes in the GSTM1 gene.
21075030 Both oral contraceptives use and GSTT1 and GSTM1 genotypes may influence IGF-1 levels.
21075030 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
21058530 Association with the development of severe perinatal asphyxia was detected for the deletion polymorphism in GSTT1 gene and the combination of the GSTT1 absent/GSTM1 absent in the newborns.
21058530 Observational study of gene-disease association. (HuGE Navigator)
21053180 Observational study of gene-disease association. (HuGE Navigator)
21051083 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
21045267 Observational study of gene-disease association. (HuGE Navigator)
21038299 Observational study of gene-disease association. (HuGE Navigator)
21037224 GSTM1 genotype is associated with bladder cancer risk and that the NAT2 genotype interacts with smoking intensity.
21037224 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20977336 The GSTM1 undeleted genotype was associated with more advanced tumor stage and worse disease-free survival.
20977336 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20972438 Observational study and genome-wide association study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20970553 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20966642 GSTM1, GSTT1, and GSTP1 genotype polymorphisms do not seem to confer any additional risk for ovarian cancer
20966642 Meta-analysis of gene-disease association. (HuGE Navigator)
20957336 Data indicate that CYP1A2*1F promoter A allele and A/A genotype and the wild-type GSTM1 allele are risk factors for the development of porphyria cutanea tarda.
20957336 Observational study of gene-disease association. (HuGE Navigator)
20954980 Results of study suggest that GSTT1 and/or GSTM1 null genotypes are associated with higher oxidative stress in both diabetic and nondiabetic chronic kidney disease.
20954980 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20951227 Data indicate that a gene-gender interaction was observed for the glutathione-S-transferase M1 (GSTM1) genotype.
20951227 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20942828 GSTM1 gene polymorphic deletion was found in patients with bladder cancer.
20942828 Observational study of gene-disease association. (HuGE Navigator)
20935060 Observational study of gene-disease association. (HuGE Navigator)
20922139 Observational study of gene-disease association. (HuGE Navigator)
20890814 Observational study of genotype prevalence. (HuGE Navigator)
20884258 The study showed absence of association for CYP1A1 2B, CYP1B1 2, GSTM1 0, and GSTT1 0 for prostate cancer
20884258 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20878561 Genetic polymorphisms of GSTM1 is associated with gastric carcinoma.
20878561 Observational study of gene-disease association. (HuGE Navigator)
20878130 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20855412 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20854097 The GSTM1 null genotype appeared to play a protective role for lung cancer in several regions of Northeast India.
20854097 Observational study of gene-disease association. (HuGE Navigator)
20853551 GSTM1 *0 *0 or GSTT1 *0 *0 or both null genotypes, do not appear to be associated with ATD-induced hepatotoxicity in our Indian population.
20853551 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20851451 biomarker of susceptibility to manganese toxicity
20851451 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20850372 Observational study of gene-disease association. (HuGE Navigator)
20847076 GSTT1 deletion is associated with severe pulmonary fibrosis; the GSTM1 deletion may have a role in the development of pleural plaques
20847076 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20846153 Hypermethylation of GSTM1 showed significant association with head and neck cancer.
20846153 Observational study of gene-disease association. (HuGE Navigator)
20845989 Observational study of gene-disease association. (HuGE Navigator)
20843117 GSTM1 deletion polymorphism is significantly associated with increased risk of symptomatic benign prostate hyperplasia.
20843117 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20842440 The objective of the present study was to investigate the role of GSTM1 and GSTT1 null genotypes as risk factors for chronic obstructive pulmonary disease (COPD) and prostate cancer.
20842440 Observational study of gene-disease association. (HuGE Navigator)
20824655 Observational study of gene-disease association. (HuGE Navigator)
20819434 Compared with the GSTM1 RsaI present genotype, the GSTM1 RsaI null genotype tended to increase susceptibility to antituberculosis drug-induced hepato-toxicity, but the association with was not significant.
20819434 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20817763 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20812880 Single nucleotide polymorphisms resulting in lower enzymatic activity in GSTM1 was found to be correlated with noise-induced hearing loss.
20812880 Observational study of gene-disease association. (HuGE Navigator)
20805158 Maternal smoking was associated with reduced childhood FEF(25-75) only in mother-child pairs with both copies of GSTM1 deleted or at least one copy of GSTT1 present
20805158 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20802377 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20797839 Our case-control study and meta-analysis could not provide sufficient evidence for the contribution of the GSTM1 copy number variation to susceptibility to schizophrenia.
20797839 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
20740495 GSTM1 null genotype may play an important role in the development of Esophageal atresia during early embryogenesis as a consequence of altered detoxification processes of xenobiotics
20740495 Observational study of gene-disease association. (HuGE Navigator)
20739761 the first study showing the association of a combined effect of GSTM1, T1 and P1 genotypes in a representative cohort of Indian patients with Type 2 diabetes mellitus
20739761 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20734807 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20732908 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20731606 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20728566 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20723587 GSTM1 null variant seemed to protect DNA integrity against oxidative damage by air pollution.
20723587 Observational study of gene-disease association. (HuGE Navigator)
20708344 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20705574 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20704749 Combined effects of cigarette smoke and GSTM1 Polymorphisms are associated with non small cell lung cancer.
20704749 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20701904 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20700368 The differences in DNA adduct levels in pterygium were associated with the genetic polymorphisms of CYP1A1 but not GSTM1.
20688591 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20686491 Meta-analysis of gene-disease association. (HuGE Navigator)
20683151 Genetic polymorphism of glutathione S transferases M1 is associated with hepatocellular carcinoma.
20683151 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20677650 No evidence is found between GSTMI genetic polymorphism and lung cancer risk among Han nationality population in Tianjin district.
20677650 Observational study of gene-disease association. (HuGE Navigator)
20676536 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20674986 This finding of this study indicated that GSTM1 candidate polymorphisms for susceptibility to Bipolar disorder among adolescents.
20674986 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20674822 genetic polymorphism is associated with atopic dermatitis in children with prenatal smoking exposure
20674822 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20672371 GSTM1-null individuals demonstrated lower busulfan pharmacokinetics in children with congenital hemoglobinopathies undergoing hematopoietic stem cell transplantation.
20672371 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20672314 GSTT1 and GSTM1 null genotypes do not associate with increased risk of hepatocellular carcinoma.
20672314 Observational study of gene-disease association. (HuGE Navigator)
20670164 Observational study and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20661823 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20661821 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20661602 The present study aimed to examine an association between the glutathione S-transferases (GSTs) polymorphisms (GSTM1, GSTT1, and GSTP1) genetic polymorphisms with the risk and expression in children with isolated Hirschsprung disease.
20661602 Observational study of gene-disease association. (HuGE Navigator)
20658008 data show that polymorphisms in GSTM1 and GSTT1 genes have no influence on the ototoxicity of aminoglycosides.
20658008 Observational study of gene-disease association. (HuGE Navigator)
20656381 There are no significant differences in overall rate, total amount of excretion, and the time of peak excretion of isothiocyanates after drinking watercress juice between the null and positive GSTT1 and M1 genotypes.
20656381 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
20656020 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20647132 In presbycusis, the GSTM1 null genotype was present in 77 percent of white Hispanics and 51 percent of white non-Hispanics.
20647132 Observational study of gene-disease association. (HuGE Navigator)
20638923 Findings suggested that CYP1A1 or GSTM1 variants may significantly modify the associations between level of serum trace metals (Cu, Zn, Se or Cr) and NSCLC, indicating the intriguing pathogenesis of lung cancer.
20638923 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20638463 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20637790 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20634891 Observational study of gene-disease association. (HuGE Navigator)
20629642 frequency of GSTM1 null (-) genotype is significantly high in infertile males when compared with the frequency in fertile males (OR = 0.32, P = 0.017, 95% CI = 0.124-0.831).
20629642 Observational study of gene-disease association. (HuGE Navigator)
20628086 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20621079 GSTM1-/GSTT1- (null) genotype may be one of the associated genetic factor for the increased risk of PTL.
20621079 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20610557 Observational study of gene-disease association, gene-gene interaction, and genetic testing. (HuGE Navigator)
20608166 Observational study of gene-disease association. (HuGE Navigator)
20599479 The probability of having CaP was increased in men who had homozygous deleted (non-functional) genotypes at GSTT1 (OR=2.17; 95% CI=1-3.79) but not GSTM1 (OR=0.89; 95% CI=0.66-1.88).
20599479 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20597111 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20596254 No clear patterns were observed between the pterygium and control groups for significant associations with GSTM1 polymorphisms.
20596254 Observational study of gene-disease association. (HuGE Navigator)
20577625 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20577141 This study aims to investigate the genotype frequencies of GSTM1, GSTT1 and GSTM3 genes in 80 osteosarcoma patients and 160 normal control participants, and also the influence of these polymorphisms in the clinical outcome of osteosarcoma patients.
20577141 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20574021 The present meta-analysis suggested that GSTM1 and GSTT1 null genotypes are associated with increased risk for senile cataract in Asian populations but not in Caucasian populations.
20574021 Meta-analysis of gene-disease association. (HuGE Navigator)
20568895 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20568049 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20563854 analysis of GSTT1 and GSTM1 gene polymorphisms in European and African populations
20563854 Observational study of genotype prevalence. (HuGE Navigator)
20563767 Observational study of gene-disease association. (HuGE Navigator)
20561699 This meta-analysis suggests null genotypes of GSTM1 and GSTT1 are both associated with increased HCC risk in Asians, and individuals with the dual null genotype of GSTM1/GSTT1 are particularly susceptible to developing HCC. Review.
20561699 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20554493 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20547950 Observational study of gene-disease association. (HuGE Navigator)
20547701 The GSTT1 and GSTM1 null genotypes, either present both or only one in a single subject, have a modifying effect on birth weight among smoking women
20547701 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20544687 Observational study of gene-disease association. (HuGE Navigator)
20540773 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20534171 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20530282 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20529763 Observational study of gene-disease association. (HuGE Navigator)
20526719 No significant associations for GSTM1 and NQO1 with either airway hyperresponsiveness or atopy were identified.
20526719 Observational study of gene-disease association. (HuGE Navigator)
20526440 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
20521623 Double deletions involving GSTT1 and GSTM1 may result in decreased GST levels, leading to increased OS as reflected by increased MDA levels.
20521623 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20517701 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20514077 Copy number variation in GSTT1 and GSTM1 predict incidence and 5-year survival from prostate and bladder cancer, and incidence of corpus uteri cancer.
20514077 Observational study of gene-disease association. (HuGE Navigator)
20511665 Observational study of gene-disease association. (HuGE Navigator)
20505681 GSTM1 or GSTT1 null genotypes, or wild type GSTP1 with GSTM1 null or GSTT1 null, increase risk for developing infertility, but the nondeletion GSTM1 and GSTT1 genotypes are protective factors
20505681 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20504102 This study suggests that GSTM1 null genotype is associated with higher risk of endometriosis.
20504102 Observational study of gene-disease association. (HuGE Navigator)
20501762 Results suggest that GSTM1 and NAT2 genotypes play an independent and interactive role in the formation of carcinogen DNA adduct in the lung.
20501762 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20495862 The GSTM1 null allele is likely not an independent risk factor for chronic obstructive pulmonary disease (COPD) but is related to emphysema, whereas the GSTT1 gene is not associated with the disease.
20495862 Observational study of gene-disease association. (HuGE Navigator)
20491576 GSTM1 copy number variations and CYP1A1 polymorphisms individually as well in interaction with tobacco consumption may increase the risk of head and neck cancer.
20491576 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20488846 The relationship between urinary HA and 8-OHdG concentration is modified by genetic polymorphisms of some metabolizing enzymes such as GSTM1, GSTT1, and ALDH2.
20488846 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20472488 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20464961 No association between frequency of chromosomal aberrations and polymorphism for GSTM1 and GSTT1 was observed.
20464961 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20464958 Observational study of gene-disease association. (HuGE Navigator)
20461808 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20459744 Clinical trial of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20459474 Observational study of gene-disease association. (HuGE Navigator)
20459366 The GST genotypes do not seem to be important in susceptibility of inflammatory bowel disease in the Danish population
20459366 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20444272 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20437058 Observational study of genetic testing. (HuGE Navigator)
20430047 Observational study of gene-disease association. (HuGE Navigator)
20426969 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20409775 No associations were observed between GSTM1 and esophageal squamous cell carcinoma.
20409775 Observational study of gene-disease association. (HuGE Navigator)
20402821 Among Indian male smokers with and without COPD, risk of COPD was not associated with the GSTM1 null genotypes.
20402821 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20401725 Ethnicity affects the genetic association of GSTM1 with rheumatoid arthritis in South Asian and Caucasian patients living in East Midlands/United Kingdom.
20401725 Observational study of gene-disease association. (HuGE Navigator)
20395963 Observational study of gene-disease association. (HuGE Navigator)
20391338 Polymorphisms in GSTM1, GSTM3, GSTT1, and GSTP1 do not influence the risk of primary glioma, at least in this population in Rio de Janeiro, Brazil.
20391338 Observational study of gene-disease association. (HuGE Navigator)
20391138 Observational study of gene-disease association. (HuGE Navigator)
20391126 Observational study of gene-disease association. (HuGE Navigator)
20390895 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20385995 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20381444 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20377137 Observational study of gene-disease association. (HuGE Navigator)
20375710 GSTM1 genotype may have a role in development of colorectal adenoma, and GSTP1 genotype may have a role in dietary chemoprevention
20375710 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20373852 Observational study of gene-disease association. (HuGE Navigator)
20370484 Association of GSTM1 and GSTT1 gene deletions with susceptibility to DNA damage in the pesticide-exposed workers.
20370484 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20368715 Observational study of gene-disease association. (HuGE Navigator)
20367187 the frequencies of GSTA1 (glutathione S-transferase alpha 1), GSTM1(GST mu 1 ), GSTO2(GST omega 2) and GSTT1(GST theta 1) genotypes found in asthmatic patients differ from those of controls
20359083 GSTM1 polymorphisms are associated with susceptibility to laryngeal and hypopharyngeal carcinomas.
20357201 Observational study of gene-disease association. (HuGE Navigator)
20354063 Genetic polymorphisms of glutathione S-transferase genes GSTM1, and risk of coronary heart disease
20354063 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
20335620 An association was observed between GSTT1 copy number variation and age-related cataract in a Han Chinese population.
20335620 Observational study of gene-disease association. (HuGE Navigator)
20331623 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20306695 Findings suggest that GSTM1 and GSTT1 polymorphisms appear to be associated with a modest increase in the risk of HCC in Egyptian patients.
20303013 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20301895 Observational study of gene-disease association. (HuGE Navigator)
20300859 There is no evidence that XRCC1 polymorphisms have advantage/disadvantage when population exposed to natural sour gas. The polymorphisms of GSTM1 and GSTT1 modulate serum testosterone concentration in young females exposed to natural sour gas.
20300859 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20297661 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20226777 Genetic polymorphisms of glutathione S-transferase M1 (GSTM1) are associated with systemic lupus erythematosus in the Chinese population.
20226777 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20216541 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20214911 our results did not reveal a consistent pattern between GSTM1 and GSTZ genotypes and increased occurrence of adverse sperm outcomes
20214911 Observational study of gene-disease association. (HuGE Navigator)
20207535 GSTM1 null allele carriers exhibited increased colorectal cancer risk in Caucasian populations (pooled OR=1.150, 95% confidence interval (CI): 1.060-1.248, random effects); no significant association was detected for Chinese subjects
20207535 Meta-analysis of gene-disease association. (HuGE Navigator)
20203006 Observational study of genetic testing. (HuGE Navigator)
20200426 Observational study of gene-disease association. (HuGE Navigator)
20197727 No significant difference was observed between subjects with dysmenorrhea and subjects without dysmenorrhea for polymorphisms of glutathione S-transferase mu 1 gene.
20197727 Observational study of gene-disease association. (HuGE Navigator)
20194081 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20194072 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20190330 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20187096 Observational study of gene-disease association. (HuGE Navigator)
20171022 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20156772 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20147336 both GSTM1 null genotype and phthalate exposure are associated with adenomyosis, leiomyoma and endometriosis
20147336 Observational study of gene-disease association. (HuGE Navigator)
20136364 Observational study of genetic testing. (HuGE Navigator)
20130515 The GSTM1 and GSTT1 null genotypes were overrepresented in papillomavirus-infected patients and in women with cervical intraepithelial neoplasia 2 or 3, although without any significant associations.
20127182 Results show that maternal smoking has a significant effect on chromosomal damage, birth weight, and length, but no correlations with GSTM1 null and OGG1 variant genotypes.
20123161 GSTM1 polymorphism is associated with an increased risk of colorecal cancer, especially in the Caucasian population.
20123161 Meta-analysis and HuGE review of gene-disease association. (HuGE Navigator)
20120433 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20110814 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20109103 the influences of the haptoglobin, MnSOD, CAT, GPX1, ACE, glutathione S-transferases M1 (GSTM1) and T1 (GSTT1) genes' polymorphisms on the oxidative stress and damage suffered by human runners was studied
20109103 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20100551 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20095411 Genetic peculiarities particularly xenobiotic detoxification enzymes CYP1A1, CYP2E1, EPHX1 and GSTM1, GSTT1 play important role in pulmonary diseases development.
20095411 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20093049 Observational study of gene-disease association. (HuGE Navigator)
20091863 Modifying effect of GSTM1 polymorphisms on the risk of early-onset lung cancer.
20091863 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20088379 Observational study of gene-disease association. (HuGE Navigator)
20085630 Clinical trial of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20083259 GSTM1 deletion polymorphism impacts renal cell carcinoma histological subtype, Fuhrman grade and metastatic behavior
20083259 Observational study of gene-disease association. (HuGE Navigator)
20074657 In contrast to patients with allogeneic blood and marrow transplantation (BMT), in patients with autologous BMT, a deletion polymorphism in GSTM1 and/or GSTT1 was significantly associated with the occurrence of overall (drug and/or radiation) toxicity.
20074657 Observational study of gene-disease association. (HuGE Navigator)
20073549 allelic polymorphisms of GSTM1 and GSTT1 were analyzed in three ethnic groups of North East India where a high prevalence of various cancers and other diseases such as hypertension, tuberculosis, and asthma have been reported
20073549 Observational study of genotype prevalence. (HuGE Navigator)
20070240 Significantly suppressed GSTM1 and GSTT1 mRNA and GSTM1 protein expression was observed in cultures of keratinocytes derived from unaffected and affected skin of vitiligo patients, and in their co-cultures with allogeneic melanocytes.
20069434 On studying the association of GSTM1 null gene polymorphisms with cervical cancer lesions, independently on smoking habit, seems to be related to a 5.7-fold increased risk of developing CLs with a considerable statistical significance (P = 0.0091).
20069434 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20063011 The Polymorphisms in GSTM1 gene alter the ability of the enzyme to metabolize carcinogens.
20063011 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20060357 positive GSTM1 genotype and enhanced GSTM1 gene expression was accompanied with increased tumor size, lymphatic metastasis status and UICC stage.
20060357 Observational study of gene-disease association. (HuGE Navigator)
20056743 Investigated the role of oxidative DNA damage, GSH concentration, GSTM1, SOD2 Ala16Val and OGG1 Ser326Cys genetic polymorphisms in susceptibility to BE disease. None of the genetic variations changed the risk of having BE disease.
20056743 Observational study of gene-disease association. (HuGE Navigator)
20056632 the inverse association between glucosinolate intake and prostate cancer risk was modified by NQO1 (C609T) and GSTM1 and GSTT1 deletion polymorphisms.
20056632 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20056207 Observational study of gene-disease association. (HuGE Navigator)
20049629 Data show that the distribution of GSTM1 and GSTT1 polymorphisms is not significantly different between lung cancer patients and the controls, suggesting that they are not independent risk factors for lung cancer.
20049629 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
20049212 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20049130 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20042523 This study suggests that isothiocyanate exposure may reduce the risk of colorectal cancer, and this protective effect may be modified by the GSTM1 and GSTT1 genes.
20042523 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
20036620 Observational study of gene-disease association. (HuGE Navigator)
20032816 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20032267 Meta-analysis of gene-disease association. (HuGE Navigator)
20029178 Observational study of gene-disease association. (HuGE Navigator)
20027111 Meta-analysis of gene-disease association. (HuGE Navigator)
20017670 single copy number variant associated with reduced mortality in colorectal neoplasm patients treated with chemotherapy
20017670 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20012094 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19996333 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19963114 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19960570 Data show that glutathione S-transferases mu and theta null genotypes were not associated with increased risk of gastric or colorectal cancer in Koreans.
19960570 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19958676 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19956635 Uncategorized study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19953622 no significant association between the susceptibility of oral cancer and genetic polymorphism for GSTA1, GSTT1, and GSTM1.
19953622 Observational study of gene-disease association. (HuGE Navigator)
19948975 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator)
19947517 The frequency of gamma-induced chromosome aberrations was correlated with the total amount of minor alleles in loci GSTP1.
19947517 Observational study of gene-disease association. (HuGE Navigator)
19936916 This meta-analysis suggests that GSTM1 null genotype is a low-penetrance risk factor for developing breast cancer.
19936916 Meta-analysis of gene-disease association. (HuGE Navigator)
19933708 Interaction between oxidative stress and GSTM1, GSTT1 and GSTP1 polymorphisms plays an important role in the pathogenesis of colorectal cancer.
19933708 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19933216 Meta-analysis of gene-disease association. (HuGE Navigator)
19927646 The GSTM1 positive genotype may be genetic risk factors for development of abnormal liver function in workers exposed to N, N-dimethylformamide.
19927646 Observational study of gene-disease association. (HuGE Navigator)
19922706 No association was found between the GSTT1 and GSTM1 null variants and laryngeal cancer.
19922706 Observational study of gene-disease association. (HuGE Navigator)
19921428 GSTM1 deletion variants did not modify breast cancer risk for 718 women BRCA1 and BRCA2 mutation carriers from Australia, the UK, Canada, and the USA.
19921428 Observational study of gene-disease association. (HuGE Navigator)
19917083 We observed a 2.1-fold increase in prostate cancer risk associated with men possessing the GSTP1 (Val/Val) and GSTM1 (*1/*1 + *1/*0) alleles
19917083 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19914269 Observational study of gene-disease association. (HuGE Navigator)
19913121 Observational study of gene-disease association. (HuGE Navigator)
19902106 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19900941 Clinical trial of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19899130 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19898482 Observational study of gene-disease association. (HuGE Navigator)
19896490 Observational study of gene-disease association. (HuGE Navigator)
19892789 The GSTM1 null-genotype frequencies were 0.66 and 0.84 among recurrent miscarriage cases and controls, respectively.
19892789 Observational study of gene-disease association. (HuGE Navigator)
19884712 The GSTM1 null genotype was present in 60% of the controls, 53.3% oral cancer patients, 50% of leukoplakia cases, and in 46.6% of the oral submucous fibrosis cases.
19884712 Observational study of gene-disease association. (HuGE Navigator)
19884647 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19874347 Results show the existence of a correlation between solar keratosis and GSTT1 null genotype which points out differences in subjects of different ethnic, geographical origin and warrants further investigation on larger and ethnically different populations
19874347 Observational study of gene-disease association. (HuGE Navigator)
19863340 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19860819 risk of asthma and asthma-related phenotypes conferred by GSTM1-null homozygosity in children is restricted to those with a history of IUS exposure.
19860819 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19860743 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19860557 The association with chronic myeloid leukemia for GSTM1 was nonsignificant.
19860557 Meta-analysis of gene-disease association and gene-gene interaction. (HuGE Navigator)
19856098 single-nucleotide polymorphisms/haplotypes in the GSTM3 gene within the GSTMs gene cluster are likely to contribute to breast cancer risk when the GSTM1 is absent
19856098 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19850945 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19843669 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19842992 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19838921 findings show that lung cancer risk with higher isothiocyanate intake may be slightly stronger among subjects with deletion of GSTM1
19838921 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19838709 aimed to compare the prevalence of GST deletions in beta thalassemia patients with controls. observed significantly higher frequency of GSTT1 (P = 0.001) and GSTT1/GSTM1 (P = 0.03) in comparison to controls.
19838709 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19823950 GST polymorphisms maybe modify the effect on markers of oxidative stress and inflammation in Chinese coronary artery disease patients.
19823950 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19818869 Genomic damages in peripheral blood lymphocytes was associated with polymorphisms of GSTM1 in workers exposed to formaldehyde.
19818869 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19816935 Meta-analysis of gene-disease association. (HuGE Navigator)
19811334 Statistically significant increased risk of AML was observed with GSTM1 null genotype. A fixed-effects model showed significant risk in the presence of null genotypes of GSTM1. No heterogeneity was seen in studies that evaluated GSTM1.
19811334 Meta-analysis of gene-disease association. (HuGE Navigator)
19801959 The degree to which rs9642880[T] and GSTM1 0/0 confer susceptibility to urinary bladder cancer seems to depend on the extent of exposure to urinary bladder carcinogens.
19800896 Polymorphisms in GSTM1 gene is significantly associated with immature sperm.
19800766 Observational study of gene-disease association. (HuGE Navigator)
19799358 Observational study of gene-disease association. (HuGE Navigator)
19799150 The frequencies of GSTM1 and GSTT1 'null' genotypes were different among ethnic groups and smear-positive pulmonary tuberculosis cases.
19796798 The GSTM1 null genotype is associated with increased airways inflammation 24 hours after ozone exposure
19786980 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19782926 GSTM1 is a potential genetic factor to predict development of essential hypertension and permit early therapeutic intervention
19782926 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19778234 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19774638 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19768671 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19763824 GSTM1 null genotype maybe associated with gastric neoplasms among Asians.
19763824 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
19760040 Meta-analysis of gene-disease association. (HuGE Navigator)
19752172 GSTM1 is a genetic marker for identification of individuals with type 1 diabetes at an increased risk for developing diabetic retinopathy.
19752172 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19751749 Observational study of gene-disease association. (HuGE Navigator)
19750077 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19748847 GSTM1 and GSTT1 genotype were not associated with survival in African American and white patients with colorectal cancer
19748847 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19741569 glutathione S-transferase mu 1 genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
19741569 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19731014 Genetic polymorphisms in GSTM1, GSTO2, XRCC1 at codons 194 and 399 may act additively for developing breast cancer
19731014 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19729828 Our study proposes role of GSTM1 polymorphism in telomere attrition and subsequent telomerase activity in oral cancer cells.
19729828 Observational study of gene-disease association. (HuGE Navigator)
19718946 Observational study of gene-disease association. (HuGE Navigator)
19710200 GSTM1 may protect against serum ascorbic acid deficiency when dietary vitamin C is insufficient.
19710200 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19705749 Observational study of gene-disease association. (HuGE Navigator)
19701760 The distribution of GSTM1 null genotypes was not significantly different between the NP patients and controls and there was also no significance between the GSTP1 genotypes and NP. GST gene polymorphisms may be important in pathogenesis of NP.
19701760 Observational study of gene-disease association. (HuGE Navigator)
19701675 GSTM1 seems to decrease sustained attention and short-term memory problems in relation to solvent exposure
19701675 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19700502 Meta-analysis of gene-disease association. (HuGE Navigator)
19696793 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19692168 Observational study of gene-disease association. (HuGE Navigator)
19669596 GSTM1 and GSTT1 polymorphisms may play a role in the development of lung cancer for some histological subtypes and modifies the risk of smoking-related lung cancer.
19669596 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19664521 Carriers of null GSTM1 genotype were at high risk of developing COPD especially when they were null GSTT1 and GSTM1 haplotype.
19664521 Observational study of gene-disease association. (HuGE Navigator)
19662515 GSTM1 and GSTT1 null genotypes have protective role(s) for developing coronary heart disease.
19662515 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19656722 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19651439 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19643819 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19643719 Observational study of gene-disease association. (HuGE Navigator)
19643173 GST genetic polymorphisms may modify the susceptibility to noise-induced temporary threshold shift in factory workers.
19643173 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19640174 Genetic polymorphisms of GSTM1 and GSTT1 were not significant risk factors for cervical cancer.
19640174 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19639480 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19636001 Observational study of genotype prevalence, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19635899 GSTM1-null was higher in the severe malarial anemia group but the difference was not significant. We conclude that GSTP1 and possibly GSTM1 may protect against severe falciparum malaria in children.
19635899 Observational study of gene-disease association. (HuGE Navigator)
19634112 XRCC1, CCND1 and GSTM1 polymorphisms have roles in oral leukoplakia after exposure to tobacco
19634112 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19629346 There was no relationship between absence the of genes GSTT1 and GSTM1 and prognosis of papillary thyroid carcinoma when compared to the AMES classifications.
19629346 Observational study of gene-disease association. (HuGE Navigator)
19625176 Observational study of gene-disease association. (HuGE Navigator)
19621425 GST-M1 genotype may influence the severity of infections in ALL children during GC administration
19621425 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19618282 Genetic polymorphisms of glutathione S-transferase genes GSTP1, GSTM1, and GSTT1 and risk of esophageal and gastric cardia cancers.
19618282 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
19610060 GSTM1 polymorphisms are associated with gastric cancer.
19610060 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19591959 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19589847 Observational study of genetic testing. (HuGE Navigator)
19589345 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19584821 In children, GSTM1 polymorphism seems to modify busulfan pharmacokinetics after intravenous drug administration.
19584821 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19582785 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19580344 combined genotypes of GSTM1 null and GSTP1 valine homozygosity (OR = 2.7, 95% CI: 1.1-6.1, chi2 = 4.5 and P = 0.03)was associated with an elevated risk of colorectal cancer.
19576039 Patients carrying GST M1-"null" genotype may be susceptible to anti-tuberculous drug induced hepatic injury.
19571817 individuals with homozygous deletion of GSTT1 and/or GSTM1 have a greater predisposition to vitiligo
19568698 GSTs may hold promise as therapeutic targets in more advanced prostate cancers, particularly, in African-Americans.
19564823 Observational study of gene-disease association. (HuGE Navigator)
19561157 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19555437 Observational study of gene-disease association. (HuGE Navigator)
19549811 data strongly support that high vegetable consumption, especially cruciferous vegetable intake, may protect against bladder cancer and that genetic variants of GSTM1 and NAT2 may modify the association.
19549811 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19548560 GSTT1 and GSTM1 genotypes had no effect on urinary 1-hydroxypyrene following PAH exposure.
19548560 Observational study of gene-environment interaction. (HuGE Navigator)
19538885 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19537956 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19535834 Women having higher concentration of polychlorinated biphenyls and GSTM1 null (*0/*0) polymorphism might have an increased susceptibility of endometriosis.
19535834 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19528963 GSTM1 (1p13.3) and GSTT2 (22q11.23) showed a statistically significant association of non-null genotypes at both loci with an additive effect for increased vulnerability to schizophrenia
19528963 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19528831 Characterize a series of polymorphisms of genes, such as CYP2E1, GSTM1, GSTT1, and particularly EPHX1, involved in butadine (BD) metabolism in very low BD exposure level.
19528831 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19521675 GSTM1null, GSTM3AB, and CYP2E1c1c2 genotypes modulate the risk of gastric cancer
19521675 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19515364 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19513514 Examine role of GSTM1 polymorphisms in patient response to gastric cancers treated with FOLFOX or FOLFIRI.
19506726 Meta-analysis of gene-disease association. (HuGE Navigator)
19498054 Differences in smoking-related effects on LINE1 methylation were observed in children with the common GSTM1 null genotype.
19498054 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19491810 Observational study of gene-disease association. (HuGE Navigator)
19486347 Patients with variant genotype of GSTM1(glutathione S-transferase mu 1) and GSTP1 (glutathione S-transferase Pi 1) were at higher risk for rejection and delayed functioning of the renal allograft, respectively
19486347 Observational study of gene-disease association. (HuGE Navigator)
19484507 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19481674 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19473562 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19469640 Observational study of gene-disease association. (HuGE Navigator)
19469619 Genetic polymorphisms of GSTM1, GSTT1 and CYP1A1 may not be risk factors for oral cancer in the Jakarta population
19469619 Observational study of gene-disease association. (HuGE Navigator)
19464563 Higher N7-MeG concentrations were observed with the GSTM1 null genotype than with the GSTM1 non-null genotype, particularly in smokers.
19448408 The polymorphism of T1270533G does not affect the detoxification function of GSTM1. The T1270533G locus has no apparent association with genetic susceptibility to nasopharyngeal cancer.
19443391 GSTM1 homozygous null genotype was associated with an increased risk of colon cancer, especially in females and in younger patients
19442564 The CYP2E1*5B and GSTM1 null alleles were significantly associated with advanced head and neck squamous cell carcinoma clinical stages (T3+T4; P=0.022 and P=0.028, respectively).
19440446 greater low birth weight risk among light-smoking mothers with the GSTM1-null genotype compared to those with GSTM1-present genotype
19430957 The genetic polymorphism of GSTT1, GSTM1 and GSTO2 N412D in three Iranian populations was detected.
19430957 Observational study of genotype prevalence. (HuGE Navigator)
19428381 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19428374 The presence of GSTM1 provides protection against the risk of lung cancer. In addition there is equivocal evidence that this protection varies with the number of gene copies.
19428374 Observational study of gene-disease association. (HuGE Navigator)
19427967 Results suggest that CYP1A1 exon7 polymorphisms may be a risk factor for esophageal cancer in Asians but not in Caucasians, whereas neither CYP1A1 Msp1 nor GSTM1 polymorphism was associated with increased susceptibility to esophageal cancer.
19427967 Observational study of gene-disease association. (HuGE Navigator)
19424928 The increase of plasma isothiocyanates concentration was independent of the GST genotype.
19424928 Clinical trial of gene-disease association. (HuGE Navigator)
19424794 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19419718 data suggest that the presence of a double deletion genotypes of the GSTM1 and GSTT1 genes is associated with hypertriglyceridemia and low HDL-cholesterol levels in humans.
19419718 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19412423 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19407363 GSTM1 null genotype is associated with benign prostate hyperplasia.
19407363 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19401526 no statistically significant associations were observed with GSTM1 polymorphisms and risk of second primary malignancy (SPM) after index squamous cell carcinoma of the head and neck development
19401526 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19394866 Risk of lung cancer increased as the number of deletion variants increased for GSTM1, although the associations were nonsignificant.
19394866 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19391035 Observational study of gene-disease association. (HuGE Navigator)
19383894 GSTM1 SNPs do not support the role of genetic variation in the catechol estrogen metabolism pathway and breast cancer risk in postmenopausal women.
19383894 Observational study of gene-disease association. (HuGE Navigator)
19380028 case-control study to assess the role of smoking, glutathione S-transferases M1 variants, null genotypes in bladder cancer development in North Tunisia.
19380028 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19376514 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19362955 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19358278 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19347979 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19343046 Observational study of gene-disease association. (HuGE Navigator)
19338664 Meta-analysis of gene-disease association. (HuGE Navigator)
19338043 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19336732 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19336475 Observational study of gene-disease association. (HuGE Navigator)
19334053 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19332728 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19330259 Observational study of gene-disease association. (HuGE Navigator)
19317600 The researchers found evidence of polymorphisms in the GSTM1*0 haplotype in a Mexican Mestizo population, which suggests an increased susceptibility to environmental carcinogens.
19317600 Observational study of genotype prevalence. (HuGE Navigator)
19307236 Observational study of gene-disease association. (HuGE Navigator)
19303722 It is suggested that NAT2 slow-acetylator, GSTM1 null, GSTM1/GSTT1-double null, and variant CYP2A6 genotypes may play important roles in the development of bladder cancer in Henan area, China
19303722 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19303595 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19287511 The results suggest that the absence of GSTM-1 enzymatic activity favors chemical actions in damaging the mtDNA.
19287511 Observational study of gene-disease association. (HuGE Navigator)
19286687 GST malfunction in GST deletion genotypes may interfere with metabolism of oxidative intermediates and may exacerbate direct or indirect pathological effects of oxidative stress on the optic nerve in the setting of these spontaneous optic neuropathies.
19286687 Observational study of gene-disease association. (HuGE Navigator)
19279659 Null GSTM1 genotype occurred more frequent in patients with resistant hypertension than those with controlled hypertension (57.1 vs 39.7%; P=0.03; RR 1.96; 95% CI 1.04-3.69) suggesting that null GSTM1 genotype may predispose to resistant hypertension.
19279659 Observational study of gene-disease association. (HuGE Navigator)
19270789 The results substantiate the cancer risk predictivity of chromosomal aberrations frequency, ruling against a strong modifying effect of GSTM1 and GSTT1 polymorphisms.
19270789 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19267064 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19265530 Observational study of gene-disease association. (HuGE Navigator)
19264525 Observational study of genotype prevalence. (HuGE Navigator)
19258736 Observational study of genotype prevalence. (HuGE Navigator)
19256768 GSTM1 polymorphism showed significant higher risk to develop acute lymphoblastic leukemia in Indian population. showed signifant higher
19256768 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19254865 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19253001 No statistically significant correlation was present between GSTM1 null and GSTT1 null genotypes with an acute rejection episode in transplant recipients.
19253001 Observational study of gene-disease association. (HuGE Navigator)
19252926 the results suggest a marked correlation of GSTM1 polymorphism with laryngeal cancer risk in Turkey population but not Caucasians and Asians.
19252926 Meta-analysis of gene-disease association. (HuGE Navigator)
19252342 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19247656 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19246429 We assessed the association of the Msp I polymorphism in CYP1A1 (*2A) and the null GSTM1 with maternal smoking behavior during pregnancy
19246429 Observational study of gene-disease association. (HuGE Navigator)
19244254 GSTM1 deficiency increases the adverse effects of maternal smoking during pregnancy on cognition in preschoolers, suggesting a interaction between child metabolic genes and tobacco smoke components in detoxification process during foetal neurodevelopment.
19244254 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19228880 a U-shaped association of GSTM1 with breast cancer, which challenges the linear gene-dosage effect of GSTM1 that was previously proposed
19228880 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
19223573 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19222528 Meta-analysis of gene-disease association. (HuGE Navigator)
19219857 Observational study of gene-disease association. (HuGE Navigator)
19218107 The missense mutation in the coding region T1270533G of GSTM1 does not affect the detoxification function, and does not have apparent relations to nasopharyngeal carcinoma susceptibility.
19218107 Observational study of gene-disease association. (HuGE Navigator)
19209780 There was a significant increased risk for bladder cancer development in patients with GST-M1 and GST-T1 combined gene deletion which was represented mainly in S. haematobium patients with bladder cancer.
19209780 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19203783 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19190172 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19183974 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19177501 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19174490 GSTM1 gene polymorphism is associated with non-small cell lung cancer.
19174490 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19169061 For GSTM1 genotypes, the overall values (controls plus patients with thyroid cancer; no.=335) indicated that the frequency of the null genotype was 49.85%.
19169061 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19161404 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19160101 GSTM1 polymorphisms is associated with oral cancer.
19160101 Meta-analysis of gene-disease association. (HuGE Navigator)
19157724 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19151739 Observational study of gene-disease association. (HuGE Navigator)
19147266 Almost half of smokers who carried a GSTM1 null genotype delivered a baby with fetal growth restriction.
19147266 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19143011 Deficiency increases susceptibility to carcinogens and likelihood of developing prostatic cancer.(REVIEW)
19143011 Meta-analysis of gene-disease association. (HuGE Navigator)
19131562 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19124514 No significant, main-effect associations were seen with a homozygous deletion of the GSTM1 polymorphism in colorectal neoplasms.
19124514 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19124506 Observational study of gene-disease association. (HuGE Navigator)
19124497 Meta-analysis of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19117770 Patients with urinary bilharziasis and GSTM1-ve and T1-ve genes might be at increased risk of bladder cancer.
19117770 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
19115684 GSTM1 (glutathione S-transferase M1) and GSTM1*0 either alone or associated with Human papilloma virus were not associated with the presence of uterine cervix adenocarcinoma
19115684 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19114965 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19102712 Polymorphisms in GSTM1 and GSTT1 genes are risk factors for coronary artery disease (CAD) in Type 2 diabetic patients, especially among smokers.
19102712 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19102379 There are no relationship between GSTT1 and GSTM1 gene deletions and hepatic damage caused by HBV.
19102379 Observational study of gene-disease association. (HuGE Navigator)
19086569 Meta-analysis of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19074750 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19062541 Observational study of genotype prevalence. (HuGE Navigator)
19057715 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19057702 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19056870 patients without GST M1 activity are more vulnerable to oxidative stress and are at greater risk for death compared with those who possess GST M1 activity
19056870 Observational study of gene-disease association. (HuGE Navigator)
19055448 These results suggest that GST polymorphisms may be a susceptibility factor to smoking-related CAD in the Chinese population
19055448 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19051221 GST-M1 gene polymorphisms do not confer increased susceptibility to tardive dyskinesia in patients with schizophrenia but TD severity might be related to GST-P1 variants
19051221 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19032232 Observational study of gene-disease association. (HuGE Navigator)
19027952 Frequencies of polymorphic variants of RAD51, XRCC3, NQO1, GSTA1, GSTM1, GSTT1, CYP3A4 and XPD enzymes were similar in patients and controls.
19027952 Observational study of gene-disease association. (HuGE Navigator)
19026998 Observational study of genetic testing. (HuGE Navigator)
19024313 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19017460 The GSTM1 gene is a genetic contributor to overall COPD susceptibility in non-Asian populations.
19017460 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
19012698 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
19009239 the presence of null genotype of GSTM1 taken together with CYP1A1 (Val/Val) genotype increases the susceptibility to Lung cancer
19009239 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
19005482 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18993042 Three isoforms of glutathione-S-transferase (GST M1, P1 and T1), have showed an association between GST M1 null, and GST M1 and T1 double null polymorphisms with increased mortality in control group.
18993042 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18992263 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18992148 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18990750 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18990742 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18990008 Observational study of gene-disease association. (HuGE Navigator)
18988661 Children who inherit a val(105) variant allele may be protected from the increased risk of asthma associated with exercise, especially in high ozone communities. GSTM1 null genotype was associated with an increased risk of asthma.
18988661 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18986377 Observational study of gene-disease association. (HuGE Navigator)
18979064 No differences for GSTM1 and GSTP1 genotype prevalence between the bladder cancer cases and the controls were observed.
18979064 Observational study of gene-disease association. (HuGE Navigator)
18977241 Observational study of gene-disease association. (HuGE Navigator)
18976645 GST activity and genotype could play an important role in modulating P. aeruginosa lung infection in CF patients.
18976645 Observational study of gene-disease association. (HuGE Navigator)
18952980 GSTM1 and GSTT1 polymorphisms may predict adverse events, including cognitive impairment after therapy, in patients with medulloblastoma
18952980 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18950733 A lack of activity in the detoxification enzymes NQO1 and GSTM, and biomarker levels are strongly associated with coronary heart disease with sex as a mitigating factor.
18950733 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18948376 No Caucasian samples contain two copies of GSTM1 but 25% of African samples have two copies of GSTM1.
18850183 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18840420 possible importance of the GSTM1 enzyme for blood pressure regulation
18840420 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18839526 The polymorphisms of GSTT1 and GSTM1 were not associated with arsenic metabolism level.
18839526 Observational study of gene-disease association. (HuGE Navigator)
18838881 GSTM1 null genotype is associated with oral cancer development
18838881 Observational study of gene-disease association. (HuGE Navigator)
18836923 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18834935 maternal genetic polymorphisms of GSTM1 and GSTT1 may modify the oxidative stress by maternal exposure to Environmental tobacco smoking(ETS).
18834935 Observational study of gene-disease association. (HuGE Navigator)
18829006 There is no association between GSTM1 polymorphism and the risk of leiomyoma in Brazilian women.
18829006 Observational study of gene-disease association. (HuGE Navigator)
18816171 GST and mEPHX variants share a positive association with viral-related hepatocellular carcinoma risk in Indian population.
18816171 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18800292 Observational study of gene-disease association. (HuGE Navigator)
18784548 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18779738 The current study suggests that the individual variation in both the cellular inflammatory modulator IL-1RN and the antioxidative property of GSTM1 may predispose individuals to an increased risk of gastric cancer.
18779738 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18778871 GSTM1 polymorphism did not affect the lung cancer risk.
18774560 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18768784 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18768514 Variants of the GSTM1 gene may modify the association between genital talc use and risk of total and serous invasive ovarian cancer.
18768514 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18768509 GSTM1 polymorphisms were not associated with an earlier age of onset for colorectal neoplasms.
18768509 Observational study of gene-disease association. (HuGE Navigator)
18760837 acute myeloid leukemia clinical outcomes were not significantly different among the GSTM1 polymorphism genotypes
18760837 Observational study of gene-disease association. (HuGE Navigator)
18725054 Diabetics with null GSTT1 genotypes are substantially at higher risk for developing complications.
18725054 Observational study of gene-disease association. (HuGE Navigator)
18720901 Observational study of genotype prevalence. (HuGE Navigator)
18713495 Meta-analysis of gene-disease association. (HuGE Navigator)
18712965 GSTM1 polymorphism is associated with nasopharyngeal carcinoma.
18712965 Observational study of genetic testing. (HuGE Navigator)
18706519 exposure to high levels of particulate matter<10 microm during the third trimester in the presence of the GSTM1 null genotype is significantly associated with the risk of preterm delivery
18706519 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18698632 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18690546 no association with bladder cancer found
18690546 Observational study of gene-disease association. (HuGE Navigator)
18683505 Observational study of gene-disease association. (HuGE Navigator)
18666559 distribution of homozygous deletions in GSTM1 and T1 in the examined groups is significantly heterogeneous
18666559 Observational study of genotype prevalence. (HuGE Navigator)
18666253 Double-null genotype for GSTT1 and GSTM1 might play role in susceptibility to develop drug-induced liver injury, as general mechanism that occurs regardless of type of drug involved, and predominantly in women.
18666253 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18645668 Observational study of gene-disease association. (HuGE Navigator)
18644106 Data show that no significant difference in intensity of GST-mu staining is observed between intractable epileptic patients and controls.
18642288 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18641537 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18641208 This study showed that green tea intervention might be effective in decreasing DNA damage in the subgroup of smokers who are GSTM1 positive regardless of their hOGG1 genotype.
18635758 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18630481 A significant association was found in Dukes' B stage colorectal cancer patients between the GSTM1 and p53 gene variants and survival.
18630481 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18630123 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18628429 GSTM1/GSTT1-double null genotype may be a risk factor for nasopharyngeal carcinoma among males in southern China.
18628429 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18618215 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18610829 polymorphic variants of genes GSTT1, GSTM1, NAT2 and MTRR can modulate the risk of childhood acute leukemia, residents of European part of Russia.
18610829 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18608187 Observational study of gene-disease association. (HuGE Navigator)
18601742 Observational study of gene-disease association. (HuGE Navigator)
18597073 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18596959 consuming broccoli interacts with GSTM1 genotype to result in complex changes to signalling pathways associated with inflammation and carcinogenesis in the prostate.
18594869 among children with steroid-sensitive nephrotic syndrome there is an association with response to cyclophosphamide therapy and combination of GSTP1 Val105 polymorphism and the null genotypes of GSTT1 and GSTM1
18594869 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18593984 Observational study of gene-disease association. (HuGE Navigator)
18591888 GSTM1 and GSTT1 null genotypes are weak, yet possible, modifiers of the risk of papillary thyroid cancer.
18591888 Observational study of gene-disease association. (HuGE Navigator)
18590468 findings corroborate metabolic genes interactions, especially for CYP1A1 462Val alleles and GSTM1 homozygous deletion, in the development of head and neck cancer in the investigated population groups in Poland
18590468 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18589596 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18583868 GSTM1/T1 null genotype contributed to the pathogenesis of smoking-related coronary artery disease to some degree
18583868 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18581889 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18580952 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18577398 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18574688 Germline genetic polymorphisms in GSTM1 is associated with breast cancer.
18574688 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18573513 there is no significant difference in the allelic variants in GSTM1 between oral submucous fibrosis and normal, while GSTT1 null gene showed significantly higher frequencies in this precancerous condition
18572765 89.8% PC patients have a mutation in one of the genes GSTT1, GSTM1 or GSTP1.
18572765 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18569591 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18569590 The elevated proportion of GSTM1 negative bladder cancer cases shows an effect of this polymorphic enzyme on development of bladder cancer; an influence of GSTM1 on the risk due to cigarette smoking was not observed.
18569590 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18569587 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18566013 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18559562 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18551009 Our studies do not provide an evidence of an association of GSTM gene variants with hypertension in humans.
18551009 Observational study of gene-disease association. (HuGE Navigator)
18550589 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18544910 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18544563 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18542066 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18521819 The only significant association between increased risk of breast cancer development and GSTs polymorphisms is found when GSTT1 null, GSTM1 null and the presence of valine in GSTP1 in codon 105 are combined.
18521819 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18507060 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18507050 CYP1A1, GSTM1 and GSTT1 polymorphisms do not appear to influence the genetic susceptibility to OSCC or the progression to more advanced stages.
18507050 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18496222 GSTM1 homozygous deletion and the CYP1A1 m1m2 variant along with tobacco use play a significant role in oral and pharyngeal cancer
18496222 Meta-analysis of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18496134 Genome-wide association study of gene-disease association. (HuGE Navigator)
18495522 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18493876 There were no statistically significant differences between myelodysplastic syndrome cases and controls for the GSTM1, GSTT1 and GSTP1 Ile105Val genotype frequencies
18493876 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18492019 Association between combinations of glutathione-S-transferase M1, T1 and P1 genotypes and non-alcoholic fatty liver disease.
18492019 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18491076 Analysis of GSTM1 gene polymorphisms suggests age-related relationships in a northern Italian population.
18491076 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18477036 the GSTM1 null genotype seems to be a possible predisposing factor for myocardial iron overload
18472644 There were some significant interactions between GST genotypes with tobacco smoking and clinocopathological factors but no association of GSTM1 with survival.
18472644 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18463401 GSTM1 polymorphisms are associated with lung cancer risk in Asian smokers.
18463401 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
18461673 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18455004 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18449862 Observational study of gene-disease association. (HuGE Navigator)
18449058 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18447907 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18444911 The GSTM1 null genotype was significantly higher among Filipino children with acute lymphoblastic leukemia. This suggests a possible role for GSTM1 null in the susceptibility of paediatric ALL cases in the Philippines.
18444911 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18443805 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18425393 CYP1B1, GSTM1, GSTT1 and GSTP1 polymorphisms may have a role in susceptibility to breast cancer
18425393 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18416133 Null genotype frequency of GSTM1 in cancer patients was higher than in healthy subjects. It was still higher in metastatic cancer disseminated to the regional lymph nodes as compared with localized tumor.
18416133 Observational study of gene-disease association. (HuGE Navigator)
18415801 different combinations of GSTP1, GSTM1 and GSTT1 polymorphisms do not greatly increase risk of lung cancer
18415801 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18414197 Genetic polymorphisms of metabolic enzymes CYP1A1, CYP2D6, GSTM1 and GSTT1 and leukemia susceptibility.
18414197 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18413200 Observational study of gene-disease association. (HuGE Navigator)
18411704 Single nucleotide polymorphism or haplotype of the gene produce risks for susceptibility to drug dependence.
18411704 Observational study of gene-disease association. (HuGE Navigator)
18409821 Observational study of gene-disease association. (HuGE Navigator)
18398695 used unconditional logistic regression analysis with GSTM1, GSTT1, and GSTO2 genotypes as predictor factors
18398695 Observational study of gene-disease association. (HuGE Navigator)
18397238 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18392488 The GSTM1 gene was deleted in 40% of the cancers and in 44.4% of controls (OR = 1.20; CI 95% 0.70 - 2.04; p=0.5659) while the GSTT1 gene was deleted in 20% and 19.5%, respectively (OR = 0.73; CI 95% 0.37-1.44; p=0.4124).
18392488 Observational study of gene-disease association. (HuGE Navigator)
18387669 Polymorphisms of CuZn-SOD, MnSOD, GSTM1 and GSTT1 in the placental tissue were not associated with preeclampsia.
18387669 Observational study of gene-disease association. (HuGE Navigator)
18385010 Observational study of genetic testing. (HuGE Navigator)
18365908 GSTT1*0 alone and in combination with GSTM1*0 and GSTP1 variant genotypes is a risk factor for gastric neoplasms in the Indian population.
18365908 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18365755 The aim of the study was to investigate NAT1, NAT2, GSTM1, GSTT1, GSTP1, SULT1A1, XRCC1, XRCC3 and XPD genetic polymorphisms, coffee consumption and risk of bladder cancer (BC) through a hospital-based case-control study.
18365755 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18334963 The overall results indicate a possible variable association between various GSTT1 and GSTM1 genotypes and glaucoma in this population.
18334963 Observational study of gene-disease association. (HuGE Navigator)
18328165 Observational study of gene-disease association. (HuGE Navigator)
18325667 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18305556 Observational study of gene-disease association. (HuGE Navigator)
18304461 GSTM1 (0/0) gene polymorphism may be linked to prostate cancer risk and early age of onset in Chinese.
18304461 Observational study of gene-disease association. (HuGE Navigator)
18304215 GSTM1 polymorphism (but not CYP2E1 RsaI polymorphism) appears to contribute to the etiology of bladder cancer in a south-eastern Chinese population
18304215 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18303971 Gene variants should be analyzed in African-American and Hispanic subjects to increase the predictive capacity of genetic tests.
18303971 Observational study of genotype prevalence. (HuGE Navigator)
18300949 The risk of hypertension was significantly increased in the GSTA1*B allele carriers having also the GSTM1 null genotype or both the GSTM1 and GSTT1 null genotypes.
18300949 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18298341 Observational study of gene-disease association. (HuGE Navigator)
18287869 persons with GSTM1 null genotype and NAT2*6B allele are at increased risk of developing AML; the risk is enhanced in persons with GSTM1 and NAT2 deficiency
18287869 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18285692 Observational study of gene-disease association. (HuGE Navigator)
18282563 Observational study of gene-disease association. (HuGE Navigator)
18280004 genetic polymorphism does not contribute to lung cancer risk in Brazilian population
18280004 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18270371 Meta-analysis and HuGE review of gene-disease association. (HuGE Navigator)
18269668 Observational study of gene-disease association. (HuGE Navigator)
18268125 PAH-DNA adduct formation could be modulated by common genetic variants in GSTM1 in African American, Dominican and Caucasian mothers and newborns.
18268125 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18262724 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18261353 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18254710 No association was detected between the GST M1 null polymorphism and sodium-lithium countertransport activity.
18254710 Observational study of gene-disease association. (HuGE Navigator)
18241825 Study reports a gene-gene interaction between CYP1A1-I462V and GSTM1 and the risk of preterm delivery.
18241825 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18240903 Observational study of genotype prevalence. (HuGE Navigator)
18224491 The aim of the present study is to investigate the influence of cytochromes P450 (CYP450) 1A1*2C and Glutathione S-transferases (GSTs) (T1 and M1) gene polymorphisms in susceptibility to chronic myeloid leukaemia (CML).
18224491 Observational study of gene-disease association. (HuGE Navigator)
18214047 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18207572 GSTM1 null genotype is associated with acute myeloid leukemia
18207572 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18203021 gene polymorphisms in CYP1A1, GSTT1, GSTP1, GSTM1, and NQO1 were characterized in Saudi individuals with a diagnosis of DLBCL; CYP1A1, GSTT1, GSTP1 demonstrated significant association of DLBCL risk; GSTM1 and NQO1 did not.
18199464 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18177825 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18162130 Absence of GST-M1 leaves more glutathione as substrate for the co-expressed GST-P1. genotyping may be a step towards a more individualized treatment of patients with metastatic testicular cancer.
18162130 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18161889 Observational study of gene-disease association. (HuGE Navigator)
18159984 NAT2 in combination with the GSTM1 genotype may strongly confer genetic susceptibility to colorectal cancer in Japanese never-smokers.
18159984 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18155166 Observational study of gene-disease association, gene-gene interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18094897 Observational study of gene-disease association. (HuGE Navigator)
18093316 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18090121 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18090121 Glutathione-S-transferase T1 and M1 and cytochrome P1A1 genetic polymporphisms do not appear to be a risk factor for cervical disease irrespective of smoking habits.
18082227 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18080216 Association between GSTM1 gene deletion and an increased risk of hereditary breast neoplasms in a case-control population.
18080216 Observational study of gene-disease association. (HuGE Navigator)
18078203 Observational study of genotype prevalence and gene-gene interaction. (HuGE Navigator)
18078203 The researchers investigated the frequnecy of the GSTM1 null allele in a Mestizo population in Mexico and found the frequency in line with other ethnic groups.
18074677 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18074677 GSTM1 polymorphism may significantly increase the risk of HNC and there is an additive interaction between GSTM1-null genotype and smoking on HNC risk.
18070799 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18067039 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18067039 significant association of null alleles with end stage renal disease
18066575 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18065725 Meta-analysis and HuGE review of gene-disease association. (HuGE Navigator)
18061941 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18058229 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18057098 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18056202 Observational study of genotype prevalence. (HuGE Navigator)
18053222 Observational study of gene-disease association. (HuGE Navigator)
18053222 These results suggest the APE1 variant genotype decreases repair of 8-OHdG and that arsenic exposure is associated with oxidative stress in women who lack a functional GSTM1 detoxification enzyme.
18035413 Overall survival and disease-free survival of CR patients in GSTT1 and GSTM1 double present group was better than in GSTT1- and/or GSTM1-gr
18035413 Observational study of gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18035380 Our data have provided evidence that GST polymorphism modifies the susceptibility to HNSCC and have further demonstrated importance of gene-environment interaction in modulating the risk to HNSCC.
18035380 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18035379 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18033323 Observational study of gene-disease association, gene-gene interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17996038 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17985662 Observational study of genotype prevalence. (HuGE Navigator)
17982751 RCC risk among smokers might be more increased with the CYP1A1*2C genotype, GSTmicro1 null, or both a CYP1A1 variant and GSTmicro1 null.
17982751 Observational study of gene-environment interaction. (HuGE Navigator)
17980001 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17979505 GSTT1-/GSTM1- genotypes are independent risk factors for development of Type 2 diabetes regardless of the smoking status and these genotypes and current smoking are interactively associated with the incidence of Type 2 diabetes.
17979505 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17965781 Observational study of gene-disease association. (HuGE Navigator)
17965781 Genetic polymorphisms of GSTM1 modulate levels of serum triglycerides, and high density lipoprotein cholesterol in females.
17953974 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17937745 Observational study of gene-disease association. (HuGE Navigator)
17922436 frequencies of GSTM1, GSTT1 and GSTP1 polymorphisms in Dong, Yi and Yao ethnic groups from Guizhou
17922436 Observational study of genotype prevalence. (HuGE Navigator)
17916905 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17916600 Observational study of genetic testing. (HuGE Navigator)
17914442 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17912498 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17908297 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17900751 we found evidence of an association between the CYP1A1 variant and GSTM1 null genotypes and increased risk of lung cancer.
17900751 Meta-analysis of gene-disease association. (HuGE Navigator)
17897446 Observational study of gene-disease association. (HuGE Navigator)
17896209 Observational study of gene-disease association. (HuGE Navigator)
17885617 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17880378 Observational study of genotype prevalence. (HuGE Navigator)
17880378 Determined frequency of GSTM1 polymorphisms in Iranian population.
17879833 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17874314 Observational study of genotype prevalence. (HuGE Navigator)
17873299 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17873299 GSTM1 polymorphism is a risk factor contributing to the development of cerebral infarct.
17870518 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17869325 Observational study of genotype prevalence. (HuGE Navigator)
17853809 Observational study of genotype prevalence. (HuGE Navigator)
17716707 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17716707 study concludes that the epistatic effect of the GSTT1 and the GSTM1 deletion polymorphism is a risk factor for increased susceptibility to mercury exposure
17714740 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17714740 GSTM1 null men showed higher % DNA fragmentation index in response to exposure to intermittent air pollution
17711870 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17707637 the significant gene-gene and gene-environment interactions of GST genes may confer a substantial risk to upper aerodigestive tract upper aerodigestive tract cancers in the Tamilian population of south India.
17707637 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17700360 Observational study of gene-disease association. (HuGE Navigator)
17696741 The frequencies for the GSTM1 Null genotype were risk factors for breast cancer.
17696741 Observational study of gene-disease association. (HuGE Navigator)
17693660 Associations between specific combinations of three GST gene polymorphisms and breast cancer risk but these did not modify the association between cruciferous vegetable intake and breast cancer.
17693660 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17684133 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17684133 Among individuals with GSTM1 null and present genotypes, the corresponding ORs were 2.91 and 4.21, respectively.
17683074 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17653748 The significant risk factor of HNSCC in young adults may be GSTM1 null genotype, which may cause the defective detoxification of metabolites of polycyclic aromatic hydrocarbons of tobacco smoke.
17653748 Observational study of gene-disease association. (HuGE Navigator)
17653713 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17653713 glutathione S transferase 1(GSTM1) genotypes do not influence the risk for Multiple Myeloma
17652311 Observational study of gene-disease association. (HuGE Navigator)
17652311 GSTM1 and GSTP1 polymorphisms may have roles in ozone-induced lung function changes
17651144 Observational study of gene-disease association. (HuGE Navigator)
17646057 Observational study of gene-disease association. (HuGE Navigator)
17646057 for esophageal and gastric adenocarcinomas, no consistent patterns of elevated risk were associated with the null GSTM1 genotypes
17644396 Observational study of gene-disease association. (HuGE Navigator)
17644396 GSTM1 polymorphisms is associated with dnan damage induced by tobacco smoke
17643058 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17643058 GSTM1 gene is a modifier of the GSTP1 gene for the risk of childhood asthma.
17631926 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17624589 GSTM1 and GSTP1 genotypes do not individually influence susceptibility to breast cancer or fibrocystic breast conditionsin Chinese women
17624589 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17617661 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17617021 Observational study of gene-disease association. (HuGE Navigator)
17611777 GSTM1 polymorphism is not associated with the risk of head and neck cancer
17611777 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17610937 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17603900 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17601350 Observational study of gene-disease association. (HuGE Navigator)
17581325 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17581325 This case-control study suggests a contribution of CYP2D6 and GSTM1 null variants in the development of acute leukaemia. In addition, GSTM1 and GSTT1 genotypes were apparently related to response, side effects and prognosis of patients with AML.
17572208 Observational study of gene-disease association. (HuGE Navigator)
17572208 GSTM1-positive genotypes are linked to a nonsignificant increase in risk in prostate cancer in a Carribean population of African descent.
17568619 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17568619 results suggest that GSTM1, not GSTT1 polymorphism is associated with vitiligo susceptibility in Korean population
17565746 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17565746 Finding suggest of an association between 7-methylguanine excretion and lung cancer risk mainly among current smokers and subjects with GSTM1 null genotype.
17565649 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17565649 Null genotypes of GSTM1 is associated with inflammatory bowel diseases.
17563610 Observational study of gene-disease association. (HuGE Navigator)
17548691 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17536768 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17531965 Observational study of gene-disease association. (HuGE Navigator)
17531965 These results suggest that the Val allele of CYP1A1 Ile462Val polymorphism and the Pro allele of TP53 Arg72Pro polymorphism contribute to an increased risk of gallbladder cancer among Japanese women and men, respectively.
17525473 hGSTM1-1 detoxifies reactive metabolites of Benzo(a)pyrene as a common mechanism of protection against cytotoxicity and mutagenicity.
17524385 Observational study of gene-disease association. (HuGE Navigator)
17524385 The GSTM1-null variant is statistically associated with the two forms of periodontitis.
17514530 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17514530 GSTM1-null genotype or combination of the GSTM1-null and GSTT1-positive genotypes in females may be associated with increased risk of cataract development in the Turkish population.
17513527 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17513317 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17508968 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17507624 Observational study of gene-disease association. (HuGE Navigator)
17505575 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17502835 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17497028 Data shows that GSTM1 null genotype was significantly associated with the increased risk of asthma.
17497028 Observational study of gene-disease association. (HuGE Navigator)
17479278 Observational study of gene-disease association. (HuGE Navigator)
17477782 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17476458 Observational study of gene-disease association. (HuGE Navigator)
17476458 no significant differences in the distributions of GSTM1 and GSTT1 genotypes between the controls and patients with reflux esophagitis or Barrett's esophagus
17469025 Observational study of gene-disease association. (HuGE Navigator)
17465707 Observational study of gene-disease association, gene-gene interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17465707 GSTM1 null genotype rather than GSTM1-/T1- was a risk factor for carbamazepine-induced mild hepatotoxicity
17461521 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17461521 Individuals with this genotype are hight susceptibble to oral squamous cell carcinoma.
17454600 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17454600 GSTM1 deletion is associated with follicular non-Hodgkin's Lymphoma
17450230 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17449559 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17448506 Observational study of gene-disease association. (HuGE Navigator)
17445838 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17439673 Observational study of gene-disease association. (HuGE Navigator)
17438538 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17437619 Observational study of gene-disease association. (HuGE Navigator)
17437619 higher incidence of GSTM1 null genotype observed in female multiple sclerosis patients, suggests a possible role of the GSTM1 detoxification pathway in a gender-dependent manner
17431481 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17429172 Observational study of gene-disease association. (HuGE Navigator)
17428724 Meta-analysis of gene-disease association. (HuGE Navigator)
17428572 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17420047 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17420047 no difference in the frequencies of the GSTM1 null genotype and the combined GSTM1 and GSTT1 null genotypes between patients and controls.
17418613 Observational study of gene-disease association. (HuGE Navigator)
17416773 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17416769 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17412371 Observational study of gene-disease association. (HuGE Navigator)
17408703 Observational study of gene-gene interaction and gene-environment interaction. (HuGE Navigator)
17408703 Smokers carrying GSTM1 deleted genotypes have an increased susceptibility to the smoking related coronary artery disease.
17403576 Observational study of gene-disease association. (HuGE Navigator)
17403576 An association of GSTM1 with Parkinson's disease supports the hypothesis that Glutathione Transferase M1 plays a role in protecting astrocytes against toxic dopamine oxidative metabolism by preventing toxic one-electron reduction of aminochrome.
17403528 Observational study of gene-disease association. (HuGE Navigator)
17401013 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17400324 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17400324 study of the relationship between genetic polymorphisms of MnSOD, NQO1, GSTM1 and GSTT1 and the susceptibility to drug-induced liver injury (DILI); GSTM1 null genotype may be related to anti-tuberculosis drug-induced hepatotoxicity
17397002 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17384900 Observational study of gene-disease association. (HuGE Navigator)
17381051 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17374652 Observational study of gene-disease association. (HuGE Navigator)
17372252 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17367411 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17365577 Observational study of gene-disease association. (HuGE Navigator)
17365577 GSTM1 is involved in arsenic metabolism in humans, and polymorphisms in the gene may play a role in susceptibility to arsenic-induced cancer
17364458 Observational study of gene-disease association. (HuGE Navigator)
17364458 GSTM1 polymorphism is not a genetic risk factor of seminal estradiol and testosterone levels in infertile men.
17363580 Observational study of gene-disease association. (HuGE Navigator)
17361553 Observational study of gene-disease association. (HuGE Navigator)
17342328 Observational study of gene-disease association. (HuGE Navigator)
17342328 It is unlikely that polymorphisms of GSTM1, GSTT1 and GSTP1 are general risk factors for melanoma in the Swedish population.
17340208 Incidence of GSTM1 null genotype was increased in bladder cancer patients compared to controls.
17340208 Observational study of gene-disease association. (HuGE Navigator)
17336217 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17333241 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17318627 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17318627 After stratification by ethnicity and gender, a statistically significant association of the GSTM1 0/0 genotype and higher arsenic content in hair was confirmed only in the subgroups of ethnic Han clan members and all male villagers.
17318621 It is conceivable that there is a relation between GSTM1 gene polymorphism and total bilirubin levels in neonatal jaundice
17318621 Observational study of gene-disease association. (HuGE Navigator)
17307803 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17307803 GSTM1 null genotype is a risk factor to OSCC among Indian tobacco habits; GSTT1 null genotype, however, emerged as a protective factor.
17307802 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17301692 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17301692 An association between polymorphisms in GSTP1 and ABCB1 and risk of acquiring intratumoral TP53 mutations suggests the existence of putative predisposing genotype backgrounds.
17298885 Observational study of gene-disease association. (HuGE Navigator)
17298885 GSTM1 gene polymorphisms are associated with lead-induced inflammatory response in a student population.
17296590 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17296590 there is no significant association between polymorphisms in CYP3A4, CYP3A5, MDR1, GSTM1 and GSTT1 and outcome either after treatment with induction chemotherapy or after high-dose therapy for multiple myeloma
17291352 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17291352 The results show significant differences between individuals with and without self-reported chemical-related sensitivity with regard to the distribution of NAT2, GSTM1, and GSTT1 gene variants.
17290402 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17290392 An increased risk of pleural mesothelioma was found in subjects bearing a GSTM1 null allele.
17284320 Observational study of gene-disease association. (HuGE Navigator)
17284320 No evidence of effect modification by GSTM1 polymorphisms on the association between arsenic exposure and skin lesions was detected.
17277043 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17265526 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17250723 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17228018 Observational study of gene-disease association. (HuGE Navigator)
17221058 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17221058 In this study the authors were unable to show a correlation between GSTM1 and GSTT1 genotypes and the development of head and neck squamous cell carcinomas in cigarette smokers.
17217536 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17206640 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17203516 Observational study of gene-disease association. (HuGE Navigator)
17203516 There is a marked difference in the frequency of common GSTM1 null genotype between Uygur and Kazakh. GSTM1 null genotype is associated with differentiation of ESCC in Kazakh.
17195228 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17194620 Observational study of genotype prevalence. (HuGE Navigator)
17194543 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17191090 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17187162 Observational study of gene-disease association. (HuGE Navigator)
17187162 In patients with idiopathic infertility, GSTM1 polymorphism might be an important source of variation in susceptibility of spermatozoa to oxidative damage.
17182005 Observational study of gene-disease association. (HuGE Navigator)
17182005 Deletion of GSTT1 gene might be considered as protective factor for hypertension.
17180579 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17179680 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17178637 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17171211 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17167268 Observational study of gene-disease association. (HuGE Navigator)
17160315 Observational study of gene-disease association. (HuGE Navigator)
17158763 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17158087 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17123660 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17119198 Observational study of gene-disease association. (HuGE Navigator)
17119046 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17119046 GSTM1, GSTT1, and GSTP1 are involved in the synergy of alcohol and tobacco in oral, pharyngeal, and laryngeal carcinoma
17118447 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17118447 GSTM1 deletions confers interindividual variability of response to treatment in patients with acute myeloid leukemia
17084623 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17083362 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17072629 Observational study of gene-disease association. (HuGE Navigator)
17071629 Observational study of gene-disease association. (HuGE Navigator)
17069592 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17064856 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17059341 Observational study of gene-disease association. (HuGE Navigator)
17059334 Observational study of genotype prevalence. (HuGE Navigator)
17035385 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17034008 Observational study of gene-disease association. (HuGE Navigator)
17026750 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17026750 associations between bladder cancer and the GSTM1 null genotype
17023730 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17022435 Observational study of gene-disease association. (HuGE Navigator)
17020091 Observational study of gene-disease association. (HuGE Navigator)
17016589 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17005168 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16998606 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16995867 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16985033 Observational study of gene-disease association. (HuGE Navigator)
16977512 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16977512 there was no difference in the frequencies of the genotypes of GSTM1 and GSTT1 between chronic obstructive pulmonary disease group and controls, but the GSTP1 Ile/Ile genotype was significantly higher in the patients than in the controls
16977343 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16973661 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16973661 GSTM1 positive genotype and GSTT1 null genotype or the combination of both may be associated with the increased risk of development of primary open-angle glaucoma in the Turkish population
16973168 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16939958 Observational study of gene-disease association. (HuGE Navigator)
16938565 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16938565 null genotypes of GSTM1 and GSTT1 can reduce detoxification capacity of GSTs as members of the xenobiotic enzyme system
16927413 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16927413 The GSTM1, GSTT1 and GSTP1 gene polymorphisms in diabetic patients and healthy individuals were investigated to test whether polymorphisms in GST genes are associated with diabetes mellitus (DM) in the Turkish population.
16921513 Observational study of gene-disease association. (HuGE Navigator)
16917939 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16914185 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16911024 Observational study of gene-disease association. (HuGE Navigator)
16906563 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16898590 Observational study of gene-disease association. (HuGE Navigator)
16887863 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16886896 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16886896 The GSTM1 null genotype, greatly increases the risk for colorectal and gastric cancers.
16884947 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16882827 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16870661 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16870661 asthmatic children with glutathione S-transferase M1 null and glutathione S-transferase P1 Valine/Valine genotypes appear more susceptible to developing respiratory symptoms related to ozone exposure
16870093 Observational study of gene-disease association. (HuGE Navigator)
16869871 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16869871 There is a significant association between the GSTM1 null genotype and rosacea.
16865249 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16864595 Observational study of gene-disease association. (HuGE Navigator)
16847185 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16839232 Observational study of genotype prevalence. (HuGE Navigator)
16837240 Observational study of gene-disease association. (HuGE Navigator)
16830058 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16829689 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16823842 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16823842 No evidence of interaction between the GSTM1 or GSTT1 polymorphisms and smoking, meat intake, green leafy vegetable intake or colorectal cancer.
16804018 The fermented papaya preparation (anti-oxidant dietary supplement) showed a significant enhancement of the antioxidant protection in GSTM1 (null) healthy elderly individuals.
16798650 Observational study of gene-disease association. (HuGE Navigator)
16788846 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16788422 In our series, the frequencies of GSTM1 and GSTT1 null genotypes did not differ from those of the control subjects.
16788422 Observational study of gene-disease association. (HuGE Navigator)
16788248 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16771603 Observational study of genotype prevalence. (HuGE Navigator)
16765145 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16760134 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16760134 To find out the association of GST variants with risk of gallbladder cancer, the distribution of polymorphisms in the GST family of genes (GSTT1, GSTM1, GSTP1, and GSTM3) were studied in 106 cancer patients and 201 healthy controls.
16758119 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16758119 findings indicated a gene-gene interaction between CYP2E1 and GSTM1 was accessible to developing breast cancer in Taiwanese women without the habits of cigarette smoking and alcohol consumption
16740387 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16721740 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16720291 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16707601 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16703596 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16702390 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16697254 Observational study of gene-disease association. (HuGE Navigator)
16676598 Meta-analysis of gene-disease association. (HuGE Navigator)
16676594 These findings suggest that GSTM1 - / - genotype alone or in combination with other defective genotypes might serve as risk factors to the etiology of ANLL.
16676594 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16642467 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16638627 Observational study of gene-disease association. (HuGE Navigator)
16631467 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16631467 This study evaluates the combined effects of genetic polymorphisms of GSTM1, GSTT1, and GSTP1 on susceptibility to cervical cancer and interaction of these genes with smoking.
16625286 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16625286 Alleles and smoking play a significant role in modified prostate cancer risk in this study population.
16624155 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16622263 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16621679 The possible links between GSTM1, GSTP1, GSTT1 and NAT2 variants and the frequency of micronuclei (MN) in human lymphocytes, was studied.
16620591 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16620556 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16620396 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16620396 GSTM1 null-genotype is a risk factor for coronary artery disease independent of genotype-smoking interaction.
16618661 Observational study of gene-disease association. (HuGE Navigator)
16615268 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16614120 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16614107 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16614106 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16614101 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16611538 Observational study of gene-disease association. (HuGE Navigator)
16599007 Observational study of gene-disease association. (HuGE Navigator)
16596290 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16580705 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16574194 Observational study of gene-disease association. (HuGE Navigator)
16567317 Observational study of gene-disease association. (HuGE Navigator)
16551760 Observational study of gene-disease association. (HuGE Navigator)
16551674 Observational study of gene-disease association. (HuGE Navigator)
16551674 XRCC1, XRCC3, GSTM1 and GSTT1 polymorphisms and chromosome damage are higher in welders than in a control group
16550944 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16536303 gstM1- and gstTl-null genotypes were associated with significantly conspicuous increasing risk of hepatocellular carcinoma.
16536303 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16535827 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16535824 There was no significant difference between the GSTM1 null group and the GSTM1 non-null group in the risk of noise induced hearing loss.
16535824 Observational study of gene-disease association. (HuGE Navigator)
16531839 Genetic polymorphisms in the GST genes could slightly modulate arsenic urinary profiles.
16523188 Observational study of gene-disease association. (HuGE Navigator)
16521944 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16520888 Observational study of gene-disease association. (HuGE Navigator)
16519766 Observational study of gene-disease association. (HuGE Navigator)
16519766 null genotype may increase the risk for oral leukoplakia
16517545 Meta-analysis of gene-disease association and gene-gene interaction. (HuGE Navigator)
16509765 Meta-analysis of gene-disease association. (HuGE Navigator)
16504378 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16496253 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16496253 The present study suggests that the GSTM1 (null) and GSTT1 (null), GSTM1 (null), and GSTP1 (mutant) combinations may be a genetic risk factor for the development of exudative age-related macular degeneration.
16493615 Observational study of gene-disease association. (HuGE Navigator)
16488119 Observational study of gene-disease association. (HuGE Navigator)
16484137 Observational study of gene-disease association. (HuGE Navigator)
16484136 Observational study of gene-disease association. (HuGE Navigator)
16481407 Maternal smoking in combination with maternal GSTM1 genetic polymorphisms may adversely affect infant birth size.
16481407 Observational study of gene-disease association. (HuGE Navigator)
16472391 an association of the homozygous GSTM1 deletion genotype with autism
16472391 Observational study of gene-disease association. (HuGE Navigator)
16471212 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16466991 Observational study of gene-disease association. (HuGE Navigator)
16459354 Observational study of gene-disease association. (HuGE Navigator)
16456144 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16452581 Observational study of gene-disease association. (HuGE Navigator)
16438295 GSTT1 and GSTM1 have no significant effect on the blood dose, measured as Hb adducts over time, after exposure to acrylamide or glycidamide
16427734 Observational study of gene-disease association. (HuGE Navigator)
16424825 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16416283 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16416283 concerted role of CYP1A1 and GSTM1 at-risk genotypes in squamous cell lung carcinoma predisposition.
16415899 Observational study of gene-disease association. (HuGE Navigator)
16413497 Observational study of gene-disease association. (HuGE Navigator)
16409207 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16395669 Observational study of gene-disease association. (HuGE Navigator)
16393248 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16390810 Observational study of gene-disease association. (HuGE Navigator)
16380991 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16365014 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16361831 Observational study of genotype prevalence. (HuGE Navigator)
16361831 frequencies of GSTM1, GSTT1, and GSTP1 polymorphisms were evaluated in 1,051 Korean male subjects
16360200 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16357600 Meta-analysis and HuGE review of genotype prevalence, gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16357593 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16353154 Observational study of gene-disease association. (HuGE Navigator)
16338071 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16338071 genetic polymorphisms of GSTT1, GSTM1, and GSTP1 are not associated with higher risk of esophageal cancer
16334806 Observational study of gene-disease association. (HuGE Navigator)
16334806 GSTM1 gene polymorphism is associated with genetic susceptibility of gastric cancer in Taiwan.
16328000 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16321221 Observational study of gene-disease association. (HuGE Navigator)
16318999 Observational study of gene-disease association. (HuGE Navigator)
16318999 The observations do not confirm the effect of the GSTM1 genotype as a risk factor for ischemic cerebrovascular disease, even in smokers.
16318816 Observational study of gene-disease association. (HuGE Navigator)
16316639 Observational study of gene-disease association. (HuGE Navigator)
16314088 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16308270 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16302194 Meta-analysis of gene-disease association. (HuGE Navigator)
16291859 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
16284498 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16283344 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16283344 this is the first evidence that the association between the frequencies of GST-M1 and GST-T1 null genotypes & Behcet's disease might be dependent on the interaction of multiple null allele polymorphisms rather than a single null allele of GST-M1 & GST-T1
16282887 Observational study of gene-disease association. (HuGE Navigator)
16273625 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16270381 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16238106 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16235998 Observational study of genetic testing. (HuGE Navigator)
16235991 Observational study of gene-disease association. (HuGE Navigator)
16235985 Observational study of gene-disease association. (HuGE Navigator)
16235982 Observational study of gene-disease association. (HuGE Navigator)
16228113 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16228113 Our study suggests the importance of combined CYP1A1, GSTM1 and GSTT1 polymorphisms in the development of smoking-induced lung cancer.
16227674 Observational study of gene-disease association. (HuGE Navigator)
16227674 impact of the polymorphisms in CYP4501A1 and GSTM1 and GSTT1 genes on the susceptibility and disease severity in 200 patients with aplastic anemia
16199080 Observational study of gene-disease association. (HuGE Navigator)
16195240 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16174455 Observational study of gene-disease association. (HuGE Navigator)
16174455 The results suggest that genetic polymorphism of GSTM1 was susceptible to HCC and individuals who are GSTM1-null have an increased risk of developing HCC
16173971 Observational study of gene-disease association. (HuGE Navigator)
16173036 Observational study of gene-disease association. (HuGE Navigator)
16173036 GSTM1-null genotype defines a subgroup of men at higher risk of prostate cancer, particularly if they are heavy smokers
16164441 Observational study of gene-disease association. (HuGE Navigator)
16162701 Observational study of gene-disease association. (HuGE Navigator)
16160620 Observational study of gene-disease association. (HuGE Navigator)
16157195 Observational study of gene-disease association. (HuGE Navigator)
16135950 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16132793 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16132793 An influence of GSTM1 null genotype for high ethanol consumption was suggested.
16125881 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16124895 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16112301 Observational study and meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
16105747 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16099114 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16098500 Observational study of genotype prevalence. (HuGE Navigator)
16097394 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16091114 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16091114 genotype may be important marker for the age of onset and risk of metastasis in oral squamous cell carcinoma
16079101 Observational study of gene-disease association. (HuGE Navigator)
16079101 Low/null activity polymorphisms of this enzyme is not with the risk of developing aplastic anemia in Caucasian patients.
16049806 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16047490 Observational study of gene-disease association. (HuGE Navigator)
16043197 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16037119 Observational study of gene-disease association. (HuGE Navigator)
16030123 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16030117 Meta-analysis of gene-disease association. (HuGE Navigator)
16027873 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16020798 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16020292 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16018936 Observational study of gene-disease association. (HuGE Navigator)
16012082 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16012082 Relative lung cancer risk for the combined 2A/null GSTM1 genotypes was 2.51, which increased with the smoking.
16009381 Observational study of gene-disease association. (HuGE Navigator)
16009381 Role of the metabolic gene polymorphisms in non-smoker lung cancer patients from the International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens.
16006997 Observational study of gene-disease association. (HuGE Navigator)
16005379 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16003747 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
16002077 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16000570 Observational study of gene-disease association. (HuGE Navigator)
15991278 Observational study of gene-disease association. (HuGE Navigator)
15981231 Observational study of gene-disease association. (HuGE Navigator)
15974302 Observational study of genotype prevalence. (HuGE Navigator)
15974302 Finds frequency of GSTM1*0/*0 significantly lower in blacks than in nonblacks in healthy blood donors from a Brazilian mixed population (Rio de Janeiro).
15968714 Observational study of gene-disease association. (HuGE Navigator)
15968714 CYP2E1 wild type (c1/c1) increased the susceptibility to esophageal squamous cell cancer risk in Kazakh individuals with GSTM1 presence genotype
15953982 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15952134 The genetic distribution of the genes in Korean is similar to the distribution of those in Chinese; more than half of the Korean in the study sample lack GSTM1 and GSTT1; the frequency for GSTM1 and GSTT1 null type of Korean is 3 times that of Indian.
15952134 Observational study of genotype prevalence. (HuGE Navigator)
15940757 Observational study of gene-disease association. (HuGE Navigator)
15940757 These results suggest that the deletion polymorphism of GSTM1 is associated with increased susceptibility for rheumatoid arthritis, particularly among individuals who are not carriers of the HLA-DRB 1 shared epitope.
15934438 Observational study of gene-disease association. (HuGE Navigator)
15932176 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15932176 Polymorphisms affecting the activity of the glutathione S-transferase isoform M1 may be associated with the risk of developing chronic severe ethanol liver damage.
15932063 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15931768 Observational study of genotype prevalence. (HuGE Navigator)
15928955 Observational study of gene-disease association. (HuGE Navigator)
15927971 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15916660 Observational study of gene-disease association. (HuGE Navigator)
15914277 Observational study of gene-disease association. (HuGE Navigator)
15914211 Observational study of gene-disease association. (HuGE Navigator)
15901999 Observational study of gene-disease association. (HuGE Navigator)
15900216 Observational study of gene-disease association. (HuGE Navigator)
15894422 Observational study of gene-disease association. (HuGE Navigator)
15891640 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15891640 We could not demonstrate any significant association between the GSTM1, GSTT1, and GSTP1 polymorphism and age-related hearing loss in this population.
15870154 Meta-analysis and HuGE review of genotype prevalence, gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator)
15866612 Observational study of gene-disease association. (HuGE Navigator)
15864623 Observational study of gene-disease association. (HuGE Navigator)
15862746 Meta-analysis of gene-disease association. (HuGE Navigator)
15861041 Observational study of gene-disease association. (HuGE Navigator)
15861041 there is an association between endometriosis and the GSTM1 null deletion, but not with GSTT1 null deletions or the CYP1A1 MspI polymorphism in South Indian women
15857854 Observational study of gene-disease association. (HuGE Navigator)
15849806 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
15845652 Observational study of gene-disease association. (HuGE Navigator)
15840612 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15838728 Observational study of gene-disease association. (HuGE Navigator)
15834859 Observational study of gene-disease association. (HuGE Navigator)
15832776 Observational study of gene-disease association. (HuGE Navigator)
15832776 polymorphisms in the GST genes are associated with increased risk of bladder cancer among Egyptians
15829318 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15812885 Observational study of gene-disease association. (HuGE Navigator)
15805147 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15801491 Observational study of gene-disease association. (HuGE Navigator)
15801482 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15790417 Observational study of gene-disease association. (HuGE Navigator)
15781210 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15777500 Observational study of gene-disease association. (HuGE Navigator)
15777499 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15770723 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15769360 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15764294 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15756908 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15748501 The genetic polymorphisms of NQO1, GSTT1 and GSTM1 led to declining of detoxifying ability in benzene metabolism, so the individual with NQO1 C609T T/T genotype, GSTT1 null genotype and GSTM1 null genotype is most susceptive to benzene poisoning.
15748501 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15747169 Observational study of gene-disease association. (HuGE Navigator)
15746160 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15738600 Observational study of gene-disease association. (HuGE Navigator)
15736440 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15734972 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15734960 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15734083 Observational study of gene-disease association. (HuGE Navigator)
15725614 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15725081 Observational study of gene-disease association. (HuGE Navigator)
15723126 Children with atopic bronchial asthma depend on the number of glutathione-S-transferase M1 mutant alleles in the genotype and on family history of asthma.
15721419 Observational study of gene-disease association. (HuGE Navigator)
15721419 GSTT1 null genotype in cervical cell samples may be associated with more severe precancerous lesions of the cervix in a Japanese population.
15717164 Observational study of gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15717164 Whereas GST-M1 null will increase cyclophosphamide efficacy, GST-P1 polymorphism seems to be related to enhanced susceptibility to further relapses.
15714076 Meta-analysis and HuGE review of genotype prevalence, gene-disease association, gene-gene interaction, gene-environment interaction, pharmacogenomic / toxicogenomic, and healthcare-related. (HuGE Navigator)
15713801 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15694665 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15688399 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15688397 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15671210 Observational study of genotype prevalence, gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15668931 Observational study of gene-disease association. (HuGE Navigator)
15668493 Meta-analysis of gene-disease association. (HuGE Navigator)
15667866 Observational study of gene-disease association. (HuGE Navigator)
15661806 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15661231 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15646021 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15642394 Observational study of gene-disease association. (HuGE Navigator)
15642394 Polymorphic in brain cancer.
15640939 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15640939 Polymorphism in GSTM1 had no statistically significant impact on lung cancer risk.
15640066 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15639977 Observational study of gene-disease association. (HuGE Navigator)
15638917 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15637738 Meta-analysis of gene-disease association. (HuGE Navigator)
15634519 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15633230 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15633230 Null genotypes are associated with incrwewas risk of hepatocellular carcinoma in southern China.
15631753 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
15627678 Observational study of gene-disease association. (HuGE Navigator)
15616829 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15612961 Observational study of gene-disease association. (HuGE Navigator)
15612961 GSTT1 and GSTM1 null genotypes and the GSTP1 Val/Val polymorphism may play important roles in asthma pathogenesis
15596296 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
15591753 Observational study of gene-disease association. (HuGE Navigator)
15588859 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15582598 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15582598 results suggest that the GSTM1 gene is one of the candidate genes that alter the baseline of systolic blood pressure in normotensive individuals
15579657 Observational study of gene-disease association. (HuGE Navigator)
15570292 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15565566 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15559321 Observational study of gene-disease association. (HuGE Navigator)
15552037 Observational study of genotype prevalence and genetic testing. (HuGE Navigator)
15548945 Observational study of gene-disease association. (HuGE Navigator)
15546237 Observational study of genotype prevalence. (HuGE Navigator)
15546237 Frequency of GSTM1 null allele in North Indian population is lower than reported in several other Asian and Caucasion populations
15538046 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15536330 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15533900 Observational study of gene-disease association. (HuGE Navigator)
15531593 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15528218 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15526353 Observational study of gene-disease association. (HuGE Navigator)
15526353 GSTM1*2/*2 and CYP1A1*1A/*2C genotype frequencies were higher among squamous cell carcinomas at a level close to statistical significance
15525789 Observational study of gene-disease association. (HuGE Navigator)
15499621 Observational study of gene-disease association. (HuGE Navigator)
15496536 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15492856 Observational study of gene-disease association. (HuGE Navigator)
15492856 No association between homozygous deletion of GSTM1 and the development of end stage renal disdease was found in either diabetic patients or hypertensive patients
15491310 Observational study of gene-disease association. (HuGE Navigator)
15491310 polymorphisms may play an important role in risk for periodontitis
15474467 Observational study of gene-disease association. (HuGE Navigator)
15473001 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15473001 GSTM1 null genotype may be associated with an increased susceptibility to gastric cancer
15472409 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15472409 Polymorphism of GSTM1 is associated with prostate cancer
15471894 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15466980 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15459223 Observational study of gene-disease association. (HuGE Navigator)
15459020 Observational study of gene-disease association. (HuGE Navigator)
15455371 Observational study of gene-disease association. (HuGE Navigator)
15454734 Observational study of gene-disease association. (HuGE Navigator)
15450429 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15382273 Observational study of gene-disease association. (HuGE Navigator)
15382272 Observational study of gene-disease association. (HuGE Navigator)
15381379 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15381379 Found no association of GSTM1 null genotype with increased risk of prostatic adenocarcinoma
15375499 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15368334 Observational study of gene-disease association. (HuGE Navigator)
15365959 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15365958 Observational study of gene-disease association. (HuGE Navigator)
15363546 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15355699 Observational study of gene-disease association. (HuGE Navigator)
15352038 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15344211 Meta-analysis of gene-disease association. (HuGE Navigator)
15344211 The fact that GSTM1 deficiency is not rare in the general population implies that the attributable risk for breast cancer could be sizable
15342448 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
15339690 Observational study of gene-disease association. (HuGE Navigator)
15338373 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15334395 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15333250 Observational study of gene-disease association. (HuGE Navigator)
15333250 the hyperinducible CYP1A1 (T6235C) mutant genotype and its mutants in combination with GSTM1 and GSTT1 null genotypes might represent a risk factor for polycystic ovaries
15327835 Observational study of gene-disease association. (HuGE Navigator)
15319294 Observational study of gene-disease association. (HuGE Navigator)
15318028 Observational study of gene-disease association. (HuGE Navigator)
15318028 In the Korean population, GSTM1 polymorphism may confer susceptibility to the development of schizophrenia but not to tardive dyskinesia.
15315337 Observational study of gene-disease association. (HuGE Navigator)
15309405 Patients with Behcet's disease(BD) showed higher prevalence of GSTM1 null genotype than controls. No relationship between null combination of GSTM1 and GSTT1 genotype polymorphisms and risk of BD.
15302996 Observational study of gene-disease association. (HuGE Navigator)
15302996 demonstrate the independent association between GSTM1 genotypes and angiogenesis and the association of GSTM1 -wild type genotype with high microvessel density index
15300848 GSTM1 copy number in asthmatic pts indicates that deletions could be a risk factor for asthma and GSTM1 might have a protective role in the development of atopic asthma.
15299090 Observational study of gene-disease association. (HuGE Navigator)
15299005 Suppresses MEKK1-mediated apoptosis and functions as a negative regulator of MEKK1.
15298956 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15288444 Observational study of gene-environment interaction. (HuGE Navigator)
15284178 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15284178 Variations in habitual consumption of fruits and vegetables among people with the GSTM1-plus genotype may contribute to variations in human rectal GST enzyme activity.
15280903 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15279067 Observational study of healthcare-related. (HuGE Navigator)
15273962 Observational study of gene-disease association. (HuGE Navigator)
15273656 Observational study of gene-disease association. (HuGE Navigator)
15273656 These results indicate GSTM1 null genotype is associated with early onset pterygium, but not associated with late onset pterygium
15256483 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15246186 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15226677 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15223862 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15219943 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15215328 Observational study of gene-disease association. (HuGE Navigator)
15215328 polymorphism and susceptibility to cirrhosis or pancreatitis in alcoholics
15213713 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15206494 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15199549 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15197518 Observational study of genotype prevalence. (HuGE Navigator)
15195126 Observational study of gene-disease association. (HuGE Navigator)
15195058 Observational study of gene-disease association. (HuGE Navigator)
15195058 GSTM1 expression is visualized in laryngeal tumor tissues in smokers
15194533 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15194507 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15192016 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15184245 Observational study of gene-disease association. (HuGE Navigator)
15184245 GSTN1 polymorphism is associated with increased risk for small cell carcinoma in smokers.
15184197 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15182232 Observational study of genetic testing. (HuGE Navigator)
15177667 Observational study of genotype prevalence. (HuGE Navigator)
15177664 Observational study of gene-disease association. (HuGE Navigator)
15167446 Observational study of gene-disease association. (HuGE Navigator)
15165083 Observational study of gene-disease association. (HuGE Navigator)
15152552 GSTM1 genotype is associated with enhances sensitivity to environmental factors
15148962 Combination of CC16, GSTM1, and GSTT1 genetic polymorphisms is associated with asthma.
15142875 Observational study of gene-disease association. (HuGE Navigator)
15141140 Observational study of gene-disease association. (HuGE Navigator)
15138056 Observational study of gene-disease association. (HuGE Navigator)
15136237 Observational study of gene-disease association. (HuGE Navigator)
15131792 Observational study of gene-disease association. (HuGE Navigator)
15128924 Observational study of gene-disease association. (HuGE Navigator)
15127559 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15125256 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15125229 Observational study of gene-disease association. (HuGE Navigator)
15122594 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15120911 Observational study of gene-disease association. (HuGE Navigator)
15120366 Observational study of gene-disease association. (HuGE Navigator)
15115915 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15113959 Observational study of gene-disease association. (HuGE Navigator)
15113959 No significant effects of GSTM1 and GSTT1 genotype on risk were observed in either menopausal group.
15112335 Observational study of gene-disease association. (HuGE Navigator)
15111988 Observational study of genotype prevalence. (HuGE Navigator)
15105047 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15102663 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15102663 GSTP1 and GSTM1 polymorphisms have a role in survival from anaplastic astrocytoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma
15099925 Observational study of gene-disease association. (HuGE Navigator)
15099925 No difference is found between Iranian smokers and nonsmokers for glutathione S-transferase M1 genetic polymorphisms.
15095308 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15093273 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15090724 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15090717 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15088107 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15085249 Observational study of gene-gene interaction. (HuGE Navigator)
15069692 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15069679 Observational study of gene-disease association. (HuGE Navigator)
15066574 Observational study of gene-disease association. (HuGE Navigator)
15066569 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15064998 Observational study of gene-disease association. (HuGE Navigator)
15064808 Observational study of genotype prevalence. (HuGE Navigator)
15061915 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15061826 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15059587 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15059587 An association was found between glutathione S-transferase M1-null genotype and endometriosis.
15059326 Observational study of gene-disease association. (HuGE Navigator)
15057507 Observational study of gene-disease association. (HuGE Navigator)
15052670 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15052670 CYP1A1 Val/Val and GSTM1 deletion genotypes are genetic susceptibility biomarkers for esophageal cancer.
15048646 Observational study of gene-disease association. (HuGE Navigator)
15048646 glutathione S-transferase M1 gene deletion is associated with the female methamphetamine abusers
15047208 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
15038404 Observational study of gene-disease association. (HuGE Navigator)
15038404 Patients with GSTM1 null genotype, 49% suffered from COPD as opposed to 21% of patients with GSTM1 plus genotype. In contrast, no differences were seen in FEV1 or FEV1/FVC when comparing patients with GSTT1 null genotype and GSTT1 plus genotype.
15036119 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15033463 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15008663 GSTM1 gene is implicated in genetic susceptibility to lung cancer among African American smokers
15006924 Observational study of gene-disease association. (HuGE Navigator)
15004652 Homozygous null GSTM1 genotype is a risk factor for the development of cancer of cervix
15004652 Observational study of gene-disease association. (HuGE Navigator)
14992466 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
14991750 Observational study of gene-disease association. (HuGE Navigator)
14980314 Observational study of gene-disease association. (HuGE Navigator)
14980314 findings suggest that the glutathione S-transferase M1 and T1 null mutatio