Tdark GLIPR1L1 GLIPR1-like protein 1

Protein Summary

Description

Plays a role in the binding between sperm and oocytes. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9-positive microvesicules found in the cauda region.

Uniprot Accession IDs

• Q6UWM5
• Q96L06

Gene Name

• GLIPR1L1

Ensembl ID

• ENST00000312442
• ENSP00000310770
• ENSG00000173401
• ENST00000378695
• ENSP00000367967

Symbol

• PRO7434
• ALKN2972

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.83
cell type or tissue	0.82
tissue sample	0.65
protein domain	0.58
cell line	0.5

Protein Classes

PANTHER Classes

Protein / Defense/immunity Protein / Glipr1-like Protein 1

DTO Classes

Protein / Immune Response / Glipr1-like Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.48   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 157   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.48   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 157   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0