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Tdark Gap junction beta-7 protein

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]

 Comments

Property Summary

NCBI Gene PubMed Count 10
PubMed Score 3.41
PubTator Score 2.31

Knowledge Summary

Patent

No data available

Expression

Synonym

Accession Q6PEY0 B3KXL0 Q96KP0
Symbols CX25
bA136M9.1
connexin25

Gene

GJB7

PANTHER Protein Class (2)

  Ortholog (1)

Species Source Disease
Horse OMA Inparanoid

 UniProt Keyword (9)

 GO Function (1)

 GO Component (2)

 GO Process (2)

 Compartment GO Term (10)

 GWAS Trait (3)

 HCA RNA Cell Line (39)

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Pathway (5)

Protein-protein Interaction (51)

GPRIN1   PRKAR2B   PALM   AHNAK   NCKAP1   CD109   GNAO1   PTPRG   EPB41L2   PYGB   GAP43   PAG1   DLG1   ERICH5   FYN   YES1   CCNY   CCNYL1   SNAP23   HRAS   NRAS   ULBP3   GNAZ   GNAQ   WASF2   UBTD1   UBTD2   EEF1A2   INA   EPHA2   EFR3B   EFR3A   AP2A1   CNTN1   PPP2R5E   GNB4   CSNK1G3   NRN1   AHNAK2   RFTN1   SVIP   ZMPSTE24   GRTP1   MICAL1   EEPD1   EFNA5   FAM171A2   ULBP2   ARVCF   PALM3   PROCR  

Gene RIF (1)

AA Sequence 

MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKNVCFDDFFP      1 - 70
ISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRKKLYVSPGTMDGGLWYAYLISLIVKTGFEIGFLV     71 - 140
LFYKLYDGFSVPYLIKCDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLKCFIKCC    141 - 210
LQKYLKKPQVLSV                                                             211 - 223
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Text Mined References (11)

PMID Year Title