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  5. PDZ domain-containing protein GIPC2

Tdark PDZ domain-containing protein GIPC2


 Comments

Property Summary

NCBI Gene PubMed Count 13
PubMed Score 3.88
PubTator Score 3.53

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (3)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.5
Disease Target Count Z-score Confidence
Crohn's disease 321 0.0 3.0

Expression

  Differential Expression (18)

Disease log2 FC p
adrenocortical carcinoma -3.099 5.7e-04
Breast cancer -2.000 5.8e-33
cutaneous lupus erythematosus -1.400 2.7e-03
cystic fibrosis -1.200 1.6e-03
ductal carcinoma in situ -1.500 1.3e-04
esophageal adenocarcinoma 1.400 1.8e-02
invasive ductal carcinoma -2.000 1.3e-04
lung adenocarcinoma -1.400 2.8e-14
lung cancer -1.100 3.2e-02
lung carcinoma -1.200 1.2e-13
malignant mesothelioma -2.500 5.3e-07
nephrosclerosis -1.712 2.9e-03
non-small cell lung cancer -1.296 7.6e-16
osteosarcoma -2.579 2.9e-04
ovarian cancer -2.700 1.6e-10
pituitary cancer 1.800 4.7e-03
psoriasis -1.600 2.0e-03
ulcerative colitis -1.300 2.0e-03

Synonym

Accession Q8TF65 Q8IYD3 Q9NXS7
Symbols SEMCAP2
SEMCAP-2

Gene

GIPC2

PANTHER Protein Class (2)

PDB

3GGE  

  Ortholog (1)

Species Source Disease
Mouse OMA EggNOG Inparanoid

 UniProt Keyword (5)

 GO Function (1)

 GO Component (2)

 Compartment GO Term (8)

 GWAS Trait (2)

 HCA RNA Cell Line (50)

See all...

Protein-protein Interaction (2)

SH3BP4   APPL1  

Gene RIF (2)

AA Sequence 

MPLKLRGKKKAKSKETAGLVEGEPTGAGGGSLSASRAPARRLVFHAQLAHGSATGRVEGFSSIQELYAQI      1 - 70
AGAFEISPSEILYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAF     71 - 140
IKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFEIELRSKA    141 - 210
GKSSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPD    211 - 280
EFAVALDETLGDFAFPDEFVFDVWGVIGDAKRRGL                                       281 - 315
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Text Mined References (15)

PMID Year Title