Tbio GIMAP2 GTPase IMAP family member 2

Protein Summary

Description

The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9UG22
• Q96L25

Gene Name

• GIMAP2

Ensembl ID

• ENST00000223293
• ENSP00000223293
• ENSG00000106560

Symbol

• IMAP2
• IAN12
• IMAP2
• HIMAP2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.97
tissue sample	0.77
molecular function	0.73
virus perturbation	0.64
tissue	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.55   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 137   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.55   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 137   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0