| Tbio | Protein NipSnap homolog 2 |
May act as a positive regulator of L-type calcium channels.
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. The encoded protein is localized to mitochondria and plays a role in oxidative phosphorylation. A pseudogene of this gene is located on the long arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. The encoded protein is localized to mitochondria and plays a role in oxidative phosphorylation. A pseudogene of this gene is located on the long arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 7.3e-05 |
| Multiple myeloma | 1332 | 1.8e-04 |
| Waldenstrons macroglobulinemia | 765 | 1.4e-02 |
| Disease | log2 FC | p |
|---|---|---|
| Multiple myeloma | 1.620 | 1.8e-04 |
| ovarian cancer | -1.400 | 7.3e-05 |
| Waldenstrons macroglobulinemia | 1.051 | 1.4e-02 |
MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKET 1 - 70 SNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEV 71 - 140 MNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAI 141 - 210 RFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPL 211 - 280 KTSPLQ 281 - 286 //
