Tbio GAS2L3 GAS2-like protein 3

Protein Summary

Description

Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.

Uniprot Accession IDs

• Q86XJ1
• B2RCN2

Gene Name

• GAS2L3

Ensembl ID

• ENST00000266754
• ENSP00000266754
• ENSG00000139354
• ENST00000539410
• ENSP00000439672
• ENST00000547754
• ENSP00000448955

Symbol

• G2L3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.97
histone modification site profile	0.86
gene perturbation	0.83
cell line	0.63
small molecule perturbation	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.03   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 96   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.03   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 96   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0