Property Summary

NCBI Gene PubMed Count 236
PubMed Score 4499.15
PubTator Score 2345.81

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (9)

Disease log2 FC p
Waldenstrons macroglobulinemia 1.501 3.3e-02
Multiple myeloma 2.044 2.5e-04
glioblastoma 1.100 2.3e-02
primary pancreatic ductal adenocarcinoma 1.300 3.0e-03
non-small cell lung cancer 1.287 1.8e-34
lung cancer 2.400 2.3e-05
pancreatic cancer 1.400 2.1e-03
lung adenocarcinoma 1.083 2.0e-07
ovarian cancer 2.900 5.0e-07

Protein-protein Interaction (8)

MLP Assay (3)

AID Type Active / Inconclusive / Inactive Description
1227 confirmatory 33 / 148 / 563 GAPDH Dose Response Colorimetric Assay
2472 screening 1950 / 0 / 289495 qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen
2795 confirmatory 84 / 135 / 1259 qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen confirmation

Gene RIF (127)

PMID Text
26713364 The results of this study led us to conclude that in cancer cells constantly exposed to conditions of oxidative stress, the protective power of Hsp70 should be abolished by specific inhibitors of Hsp70 expression.
26626483 Data revealed that GAPDH is a phosphorylation substrate for AMPK and its interaction with Sirt1 in the nucleus. The phosphorylation and the nuclear translocation of GAPDH mediate rapid Sirt1 activation and autophagy initiation under glucose deprivation.
26564736 This review will summarize our current understanding of GAPDH-mediated regulation of RNA function
26527100 analysis of PSCA level in the peripheral blood of PC patients who underwent radical prostatectomy shows it is related to a GADPH reference level (PSCA/GAPDH ratio)
26438826 findings demonstrate that dissociation of the GAPDH/Siah1 pro-apoptotic complex can block high glucose-induced pericyte apoptosis, widely considered a hallmark feature of diabetic retinopathy
26359500 suggests that GAPDH aggregates accelerate Abeta amyloidogenesis, subsequently leading to mitochondrial dysfunction and neuronal cell death in the pathogenesis of AD
26279122 transient silencing of GAPDH reduces intracellular ROS and facilitates increased autophagy, thereby reducing acute hypoxia and reoxygenation injury as well as the resulting apoptosis and necrosis.
26258539 Genetic variants in GAPDH confer susceptibility to sporadic Parkinson's disease in a Chinese Han population.
26255202 The activity of GAPDS was significantly positively correlated with sperm motility and negatively with the incidence of infertility.
26203648 The level of GAPDH-AP DNA adduct formation depends on oxidation of the protein SH-groups; disulfide bond reduction in GAPDH leads to the loss of its ability to form the adducts with AP DNA
25944804 GAPDH and protoporphyrinogen oxidase were shown to have higher expression in faster growing cell lines and primary tumors. Pharmacologic inhibition of GAPDH or PPOX reduced the growth of colon cancer cells in vitro
25944651 The levels of GAPDH protein were significantly up-regulated in lung squamous cell carcinoma tissues and elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
25882840 The N terminus of nuclear GAPDH binds with PARP-1, and this complex promotes PARP-1 overactivation both in vitro and in vivo.
25870284 astrocytic production of D-serine is modulated by glycolytic activity via interactions between GAPDH and SRR.
25785838 Extracellular GAPDH, or its N-terminal domain, inhibited gastric cancer cell growth. GAPDH bound to E-cadherin and downregulated the mTOR-p70S6 kinase pathway.
25550585 GAPDH expression is deregulated during melanoma progression.
25496916 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS
25451934 Dimer and tetramer interface residues in adenine-uridine rich elements are important for GAPDH-RNA binding.
25394713 deregulated GAPDH expression promotes NF-kappaB-dependent induction of HIF-1alpha and has a key role in lymphoma vascularization and aggressiveness
25391652 Siah1 is a substrate of ASK1 for activation of the GAPDH-Siah1 oxidative stress signaling cascade.
25189828 In 60 % of patients with type 2 diabetes, a reversible inhibition of GAPDH is observed.
25086035 Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase.
25065746 MZF-1 binds to and positively regulates the GAPDH promoter, indicating a role for GAPDH in calcitriol-mediated signaling.
25009227 analysis of how flux through GAPDH is a limiting step in aerobic glycolysis
24375405 TG2-dependent GAPDH deamidation was suggested to participate in actin cytoskeletal remodeling.
24362262 acetylation of GAPDH (K254) is reversibly regulated by the acetyltransferase PCAF and the deacetylase HDAC5.
24018444 This review describes the structure and localization of GAPDH in cells as well as the latest discoveries on the multifunctional properties of the enzyme.
23988223 GAPDH gene over expression in resected tumor samples is an adverse prognostic factor in non small cell lung cancer.
23874603 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS
23728617 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS
23645209 GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death.
23620736 The data presented demonstrate that up-regulation of GAPDH positively associated genes is proportional to the malignant stage of various tumors and is associated with an unfavourable prognosis.
23527007 In a yeast two-hybrid screen of a heart cDNA library with Mst1 as bait, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was identified as an Mst1-interacting protein.
23409959 GAPDH binds to alkylated, single-stranded, double-stranded and telomeric sequences in a drug-dependent and DNA sequence/structure-dependent manner.
23348613 interaction between prolyl oligopeptidase and glyceraldehyde-3-phosphate dehydrogenase is required for cytosine arabinoside-induced glyceraldehyde-3-phosphate dehydrogenase nuclear translocation and cell death
23332158 NleB, a bacterial glycosyltransferase, targets GAPDH function to inhibit NF-kappaB activation.
23237566 GAPDH negatively regulates HIV-1 infection and provide insights into a novel function of GAPDH in the HIV-1 life cycle and a new host defense mechanism against HIV-1 infection.
23237566 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS
23237566 Knockdown of GAPDH by siRNA enhances HIV-1 infectivity in TZM-bl cells
23125841 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS
23086952 The ability of C1q to sense both human and bacterial GAPDHs sheds new insights on the role of this important defense collagen molecule in modulating the immune response.
22964641 Results indicate that CIB1 is uniquely positioned to regulate PI3K/AKT and MEK/ERK signaling and that simultaneous disruption of these pathways synergistically induces a nuclear GAPDH-dependent cell death.
22957700 The strength, selectivity, reversibility, and redox sensitivity of heme binding to GAPDH are consistent with it performing heme sensing or heme chaperone-like functions in cells.
22847419 GAPDH is regulated to target the telomerase complex, resulting in an arrest of telomere maintenance and cancer cell proliferation.
22832495 The protein encoded by this gene contains a peptide that displays antimicrobial activity against E. coli, P. aeruginosa, and C. albicans.
22789853 SIRT1 functions to retain GAPDH in the cytosol, protecting the enzyme from nuclear translocation via interaction with these two proteins.
22613203 AIRE-induced apoptosis pathway is associated with GAPDH nuclear translocation and induction of NO-induced cellular stress in AIRE-expressing cells.
22534308 Glyceraldehyde-3-phosphate prevents cells from apoptosis by lowering S-nitrosylation of GAPDH.
22350014 GAPDH expression was significantly up-regulated in colorectal carcinoma tissues, and also increased in colon cancer cell lines and thus may be a potential target for colon cancer therapy.
22189680 p53 may not be necessary for the S-nitrosoglutathione-induced translocation of GAPDH to the nucleus during apoptotic cell death in hepatoma cells
22174317 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS
21979951 Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation
21895736 The present mini review summarizes recent findings relating to the extraglycolytic functions of GAPDH and highlights the significant role this enzyme plays in regulating both cell survival and apoptotic death--{REVIEW}
21749859 these results show that GAPDH-depleted cells establish senescence phenotype, as revealed by proliferation arrest, changes in morphology, SA-beta-galactosidase staining, and more than 2-fold up-regulation of senescence-associated genes DEC1 and GLB1.
21539808 in the absence of PABP, the glycolytic enzyme GAPDH translocated to the cell nucleus and activated the GAPDH mediated apoptotic pathway by enhancing acetylation and serine 46 phosphorylation of p53.
21338575 In MCF-7 cells, the activation of HIF1 on the novel hypoxia response element contributes to the breast cancer-specific hypoxic induction of GAPDH gene expression and absolutely depends on the presence of Sp1 on the GC-box.
21336310 p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
21236242 the glycolytic enzyme GAPDH regulates the gene expression of ccn2 mRNA in trans by acting as a sensor of oxidative stress and redox signals, leading to CCN2 overexpression under the condition of hypoxia and promotion of angiogenesis.
21073742 GAPDH was identified as a binding protein on the plasma membrane of CEM-SS leukemia cells for Bt18 parasporal protein.
20864222 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
20800603 Observational study of gene-disease association. (HuGE Navigator)
20727968 GAPDH is a moonlighting protein that functions as a glycolytic enzyme as well as a uracil DNA glycosylase.
20707929 The study demonstrated that GAPDH is reliable as reference gene for quantitative gene expression analysis in human diploid fibroblasts.
20664973 Showed the presence of GAPDH in the plasma membrane of four different breast cancer cell lines.
20610654 increased intrathecal production of GAPDH-reactive Abs in patients with MS may result in widespread binding of Abs to GAPDH in axons and neurons, leading to inhibition of GAPDH glycolytic activity, neuroaxonal apoptosis, and cytotoxicity.
20471030 This protein has been found differentially expressed in thalami from patients with schizophrenia.
20407807 Shear stress especially induced sustained increases in the expression of Annexin A2 and GAPDH in a comparative proteome analysis of effect of shear stress on HMSCs.
20381070 This protein has been found differentially expressed in the anterior cingulate cortex in women patients with schizophrenia.
20181627 melanoma antigen expressed in G361, a representative melanoma cell line/ reacted with autoantibodies in patient sera
20177150 The nuclear translocation of GAPDH might be regulated by the PI3K signaling pathway acting mainly as a nuclear export signal and the AMPK signaling pathway acting as a nuclear import signal.
19940145 siah-1 Protein is necessary for high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation and cell death in Muller
19874799 These results suggest that aggregate-prone mutations of GAPDH such as S284C-GAPDH may confer risk of oxidative stress-induced cell death.
19837666 GAPDH aggregates have a critical role in oxidative stress-induced brain damage
19800890 Overall, these data demonstrate that GAPDH binds telomeric DNA directly in vitro and may have a biological role in the protection of telomeres against rapid degradation in response to chemotherapeutic agents in A549 human lung cancer cells.
19747091 GAPDH from cancer is distinctly different from the normal cellular GAPDH.
19650766 Oxidatively modified GAPDH regulates its cellular functions by changing its interacting proteins.
19621076 Promoter occupancy studies by chromatin immunoprecipitation assay revealed nuclear GAPDH could be detected in promoter of genes that were up-regulated during T cell activation, but not in the promoter of genes that were not unaffected or down-regulated
19605696 A novel function is demonstrated for GAPDH as a mononuclear cell receptor for human cathelicidin LL-37 in the functioning of cationic host defense peptides.
19464723 confirm the interactions of eEF1A1, p54(nrb), hnRNP-L, GAPDH and ASF/SF2 with the right terminal stem-loop domain of HDV genomic RNA in vitro
19430704 Study show that the new protocol represents a simple, economic, and reproducible tool for the purification of GAPDH and can be used for other proteins.
19405953 This protein has been found differentially expressed in the Wernicke's Area from patients with schizophrenia.
19165527 Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
19161537 U6snRNA, GAPDH mRNA and CPEB1 mRNA levels may be useful as tumor markers for genital cancers.
18776667 Involvement of GAPDH in the X-ray resistance of HeLa cells is reported.
18776186 the nuclear translocation of GAPDH during oxidative stress constitutes a protective mechanism to safeguard the genome by preventing structural inactivation of APE1.
18708368 GAPDH, a multifunctional protein, now adds regulation of mRNA stability to its repertoire.
18682386 A redox-modulated direct p38/GAPDH-Oct-1 interaction nucleates the occupancy of the H2B promoter by the OCA-S complex, in which p36/LDH plays a critical role in the hierarchical organization of the complex.
18552833 Results show that nuclear GAPDH is acetylated at Lys 160 by the acetyltransferase p300/CREB binding protein (CBP) through direct protein interaction, which in turn stimulates the acetylation and catalytic activity of p300/CBP.
18448829 Succination of GAPDH and other thiol proteins may provide the chemical link between glucotoxicity and the pathogenesis of diabetic complications.
18340469 Observational study of gene-disease association. (HuGE Navigator)
18163542 Overexpression of human GAPDH in Escherichia coli did not enhance mutagenesis by diepoxybutane.
17989880 These results suggest that the polyQ domain, but not the polyP domain, plays a role in the sequestration of GAPDH to aggregates by mutant htt
17597534 Study observed no hypoxia-induced regulation of GAPDH expression in the 3 glioblastoma cell lines; also, GAPDH expression was similar in patient tumor samples of low-grade astrocytoma and glioblastoma, suggesting a lack of hypoxic regulation in vivo.
17553795 Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells
17540725 Nitric oxide-mediated S-nitrosylation of GAPDH and subsequent nuclear translocation of GAPDH might function as a mediator of TRAIL-induced cell death in thyroid cancer cells.
17387692 alpha-crystallin B, glyceraldehyde phosphate dehydrogenase (GAPDH), and alpha-enolase identified as significantly S-glutathionylated in Alzheimer's disease infeior parietal lobule
17324518 A decrease in the dehydrogenase activity of GAPDH was noted in Alzheimer disease.
17121833 GAPDH interacts with transferrin and the GAPDH-transferrin complex is subsequently internalized into the early endosomes.
17027006 identified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a new interacting partner of TPPP/p25 within the alpha-synuclein positive Lewy body
17015754 TPI and GAPDH may be candidate Ags for an autoimmune response to neurons and axons in multiple sclerosis.
16832079 The GAPD gene and its pseudogene may play a role in the development of late-onset Alzheimer disease. However, the effect, if any, is likely to be limited.
16778134 OxLDL downregulated GAPDH via a H2O2-dependent decrease in protein stability. GAPDH protein damage resulted in marked depletion of cellular ATP levels.
16515701 GAPDH is inaccurate to normalize mRNA levels in studies investigating the effect of bisphosphonates on gene expression; this gene could be considered a potential target to observe the effects of bisphosphonates on cancer cells
16474839 GAPDH might be involved in cell cycle regulation by modulating cyclin B-cdk1 activity.
16186172 Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease
16139273 Data show that the insertion of ferriprotoporphyrin IX (FP) into the red cell membranes exerts two opposite effects on membrane bound G3PD.
16082386 GAPDH is an integral part of the sarcolemmal K(ATP)-channel protein complex, where it couples glycolysis with the K(ATP)-channel activity.
16037232 Conditions associated with elevated intracellular methylglyoxal could modify GAPDH activity in vivo.
15985219 evidence that GAPDH is an epithelial binding receptor for Porphyromonas gingivalis fimbriae
15907785 GAPDH modified by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal is degraded by a giant serine protease, releasing the 23-kDa fragment, not by proteasome or TPP I
15769908 Marked variability of GAPDH expression between tissue types which establish comparative levels of expression and can be used to add value to gene expression data in which GAPDH is used as the internal control.
15746184 results demonstrate that glyceraldehyde-3-phosphate dehydrogenase, a glycolytic and microtubule binding protein, co-localized to neurofibrillary tangles and immunoprecipitated with paired helical filament-tau
15716040 Subcellular interactions may mitigate oxidative stress-induced GAPDH modification in human aging.
15507493 Observational study of gene-disease association. (HuGE Navigator)
15507493 significant association between late-onset Alzheimer's disease and a compound genotype of the three GAPD genes
15485821 data suggest that glyceraldehyde-3-phosphate dehydrogenase (GAPDH) imparts a unique function necessary for membrane trafficking from vesicular tubular clusters (VTCs) that does not require GAPDH glycolytic activity
15001839 GAPDH mRNA expression was correlated with evidence of tumor progression in thymoma.
14730345 Thioredoxin regulates the expression of GAPDH.
14630908 nuclear GAPDH has a role in the maintenance and/or protection of telomeres
14515148 Glyceraldehyde-3-phosphate dehydrogenase might be a novel target for vaccinia anti-apoptotic modulation.
12921788 Glycoaldehyde inactivates GAPD.
12842822 Transcription factors bound to glutamine-responsive element in GAPDH promoter are C/EBPalpha and -delta.
12697324 HIF-2alpha regulates glyceraldehyde-3-phosphate dehydrogenase gene expression in vascular endothelial cells.
12503091 dissociation of the GAPDH protein from the HMW species restores its enzymatic activity.
12428732 GAPDH may be involved in the cellular phenotype of age-related neurodegenerative disorders--REVIEW
12121569 GAPDH is not an ideal internal standard for specific gene expression in testicular tissue specimens
12008025 We identified a nuclear high molecular weight (HMW) GAPDH species in Huntington's disease cells, suggesting a connection between nuclear GAPDH function and huntingtin localization in this CAG expansion neuronal disease.

AA Sequence

MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVIN      1 - 70
GNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKY     71 - 140
DNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPAS    141 - 210
TGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQ    211 - 280
VVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE                   281 - 335
//

Text Mined References (256)

PMID Year Title
26713364 2016 Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH.
26626483 2015 AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation.
26564736 The sweet side of RNA regulation: glyceraldehyde-3-phosphate dehydrogenase as a noncanonical RNA-binding protein.
26527100 2015 The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy.
26465922 2016 Altered ?-synuclein, parkin, and synphilin isoform levels in multiple system atrophy brains.
26438826 2015 High Glucose-induced Retinal Pericyte Apoptosis Depends on Association of GAPDH and Siah1.
26359500 2015 Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-? Amyloidogenesis in Alzheimer Disease.
26279122 2015 GAPDH-silence preserves H9C2 cells from acute hypoxia and reoxygenation injury.
26258539 2015 Genetic variants in GAPDH confer susceptibility to sporadic Parkinson's disease in a Chinese Han population.
26255202 2015 Oxidation of glyceraldehyde-3-phosphate dehydrogenase decreases sperm motility in diabetes mellitus.
26203648 2015 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interacts with apurinic/apyrimidinic sites in DNA.
25944804 2015 Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25944651 2015 Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
25900259 2015 Periostin of human periodontal ligament fibroblasts promotes migration of human mesenchymal stem cell through the ?v?3 integrin/FAK/PI3K/Akt pathway.
25882840 2015 Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke.
25870284 2015 Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes.
25856795 2015 Acacetin inhibits expression of matrix metalloproteinases via a MAPK-dependent mechanism in fibroblast-like synoviocytes.
25808196 2015 Intensified antineoplastic effect by combining an HDAC-inhibitor, an mTOR-inhibitor and low dosed interferon alpha in prostate cancer cells.
25785838 2015 Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNF?-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction.
25689150 2015 Autophagy modulates the effects of bis-anthracycline WP631 on p53-deficient prostate cancer cells.
25550585 2015 Deregulation of glyceraldehyde-3-phosphate dehydrogenase expression during tumor progression of human cutaneous melanoma.
25451934 2015 A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA.
25417112 2014 Target-selective protein S-nitrosylation by sequence motif recognition.
25394713 2015 GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-?B-dependent induction of HIF-1?.
25391652 2015 Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade.
25189828 2015 [Contribution to the study of glyceraldehyde-3-phosphate dehydrogenase in patients with type 2 diabetes].
25086035 2014 Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase.
25065746 2014 The glyceraldehyde 3-phosphate dehydrogenase gene (GAPDH) is regulated by myeloid zinc finger 1 (MZF-1) and is induced by calcitriol.
25009227 2014 Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.
24992036 2014 G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.
24658140 2014 The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.
24375405 2014 Transglutaminase 2-dependent deamidation of glyceraldehyde-3-phosphate dehydrogenase promotes trophoblastic cell fusion.
24362262 2014 Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
24101517 2013 Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity.
24018444 2013 [Properties and functional diversity of glyceraldehyde-3-phosphate dehydrogenase].
23988223 2013 Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients.
23979707 2013 SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
23823123 2013 Systematic Analysis Reveals Elongation Factor 2 and ?-Enolase as Novel Interaction Partners of AKT2.
23645209 2013 GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death.
23620736 2013 The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (GACC) genes correlates with cancer stage and poor survival in patients with solid tumors.
23533145 2013 In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
23527007 2013 Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis.
23409959 2013 Protein recognition of the S23906-1-DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH).
23376485 2013 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
23348613 2013 Prolyl oligopeptidase is a glyceraldehyde-3-phosphate dehydrogenase-binding protein that regulates genotoxic stress-induced cell death.
23332158 2013 NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-?B activation.
23237566 2012 Glyceraldehyde 3-phosphate dehydrogenase negatively regulates human immunodeficiency virus type 1 infection.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
23091630 2012 Housekeeping gene selection advisory: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and ?-actin are targets of miR-644a.
23086952 2012 Human and pneumococcal cell surface glyceraldehyde-3-phosphate dehydrogenase (GAPDH) proteins are both ligands of human C1q protein.
23071094 2012 Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.
22964641 2013 CIB1 prevents nuclear GAPDH accumulation and non-apoptotic tumor cell death via AKT and ERK signaling.
22963082 2012 Detection of human herpesvirus 8 by quantitative polymerase chain reaction: development and standardisation of methods.
22957700 2012 Heme binding properties of glyceraldehyde-3-phosphate dehydrogenase.
22905912 2012 Resveratrol-induced changes of the human adipocyte secretion profile.
22847419 2012 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component.
22832495 2013 A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
22789853 2012 SIRT1 interacts with and protects glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from nuclear translocation: implications for cell survival after irradiation.
22771119 2012 Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation.
22613203 2012 AIRE-induced apoptosis is associated with nuclear translocation of stress sensor protein GAPDH.
22534308 2012 Glyceraldehyde-3-phosphate, a glycolytic intermediate, prevents cells from apoptosis by lowering S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase.
22350014 2012 Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester.
22189680 2011 p53 is not necessary for nuclear translocation of GAPDH during NO-induced apoptosis.
21988832 2011 Toward an understanding of the protein interaction network of the human liver.
21979951 2011 Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation.
21908771 2011 The first identification of lysine malonylation substrates and its regulatory enzyme.
21895736 2012 GAPDH: a common enzyme with uncommon functions.
21749859 2011 Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells.
21630459 2011 Proteomic characterization of the human sperm nucleus.
21539808 2011 In the absence of cellular poly (A) binding protein, the glycolytic enzyme GAPDH translocated to the cell nucleus and activated the GAPDH mediated apoptotic pathway by enhancing acetylation and serine 46 phosphorylation of p53.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
21362503 2011 Protein profile of exosomes from trabecular meshwork cells.
21338575 2011 Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells.
21336310 2011 p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase.
21269460 2011 Initial characterization of the human central proteome.
21236242 2011 Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA.
21073742 2010 Identification of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a binding protein for a 68-kDa Bacillus thuringiensis parasporal protein cytotoxic against leukaemic cells.
21044950 2011 Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
20864222 2012 Association and heterogeneity at the GAPDH locus in Alzheimer's disease.
20849852 2010 Proliferating cell nuclear antigen in the cytoplasm interacts with components of glycolysis and cancer.
20800603 2010 Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
20727968 2011 The diverse functions of GAPDH: views from different subcellular compartments.
20707929 2010 Effect of experimental treatment on GAPDH mRNA expression as a housekeeping gene in human diploid fibroblasts.
20664973 2010 Glyceraldehyde-3-phosphate dehydrogenase as a surface associated antigen on human breast cancer cell lines MACL-1 and MGSO-3.
20644585 [Haponin (eIF1AD) interacts with glyceraldehyde 3-phosphate dehydrogenase in the CHO-K1 cell line].
20610654 2010 Inhibition of glyceraldehyde-3-phosphate dehydrogenase activity by antibodies present in the cerebrospinal fluid of patients with multiple sclerosis.
20471030 2010 Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.
20458337 MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
20407807 2010 Proteomic profiling of human bone marrow mesenchymal stem cells under shear stress.
20392205 2010 Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy in living cells.
20381070 2010 Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia.
20181627 Identification of melanoma antigens using a Serological Proteome Approach (SERPA).
20177150 2010 Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
20029029 2009 Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.
19946888 2010 Defining the membrane proteome of NK cells.
19940145 2010 siah-1 Protein is necessary for high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation and cell death in Muller cells.
19874799 2009 An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells.
19837666 2009 Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death.
19800890 2009 Direct binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradation.
19747091 2009 Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19650766 2009 Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions.
19621076 2009 Proteomic analysis of the differential protein expression reveals nuclear GAPDH in activated T lymphocytes.
19608861 2009 Lysine acetylation targets protein complexes and co-regulates major cellular functions.
19605696 2009 Intracellular receptor for human host defense peptide LL-37 in monocytes.
19464723 2009 The hepatitis delta virus RNA genome interacts with eEF1A1, p54(nrb), hnRNP-L, GAPDH and ASF/SF2.
19430704 2009 Immunoaffinity purification and characterization of glyceraldehyde-3-phosphate dehydrogenase from human erythrocytes.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
19405953 2009 Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation.
19199708 2009 Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
19190083 2009 Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
19165527 2009 Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
19161537 2009 Expression of CPEB, GAPDH and U6snRNA in cervical and ovarian tissue during cancer development.
19056867 2009 Large-scale proteomics and phosphoproteomics of urinary exosomes.
19001379 2009 FKBP36 is an inherent multifunctional glyceraldehyde-3-phosphate dehydrogenase inhibitor.
18776667 2008 Involvement of glyceraldehyde-3-phosphate dehydrogenase in the X-Ray resistance of HeLa cells.
18776186 2008 Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1.
18708368 2008 The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer.
18682386 2008 Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
18552833 2008 Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis.
18448829 2008 Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes.
18364388 2008 A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes.
18340469 2008 Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease.
18183946 2008 Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase.
18163542 2008 Reactions of glyceraldehyde 3-phosphate dehydrogenase sulfhydryl groups with bis-electrophiles produce DNA-protein cross-links but not mutations.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17989880 2007 Sequestration of glyceraldehyde-3-phosphate dehydrogenase to aggregates formed by mutant huntingtin.
17597534 2007 GAPDH is not regulated in human glioblastoma under hypoxic conditions.
17553795 2007 Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells.
17540725 2007 Involvement of glyceraldehyde-3-phosphate dehydrogenase in tumor necrosis factor-related apoptosis-inducing ligand-mediated death of thyroid cancer cells.
17540579 2007 A mutation in human VAP-B--MSP domain, present in ALS patients, affects the interaction with other cellular proteins.
17456004 2007 Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors.
17387692 2007 An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach.
17373842 2007 HDM2-binding partners: interaction with translation elongation factor EF1alpha.
17353931 2007 Large-scale mapping of human protein-protein interactions by mass spectrometry.
17324518 2007 Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease.
17121833 2007 The macrophage cell surface glyceraldehyde-3-phosphate dehydrogenase is a novel transferrin receptor.
17081983 2006 Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
17027006 2006 Interaction of TPPP/p25 protein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodies.
17015754 2006 Triosephosphate isomerase- and glyceraldehyde-3-phosphate dehydrogenase-reactive autoantibodies in the cerebrospinal fluid of patients with multiple sclerosis.
16892178 2006 Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro.
16832079 2006 Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease.
16815975 2006 HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets.
16799092 2006 Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA).
16778134 2006 Novel effect of oxidized low-density lipoprotein: cellular ATP depletion via downregulation of glyceraldehyde-3-phosphate dehydrogenase.
16751257 2006 Housekeeping genes for phylogenetic analysis of eutherian relationships.
16713569 2006 A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
16682416 2006 Reversible post-translational modification of proteins by nitrated fatty acids in vivo.
16541075 2006 The finished DNA sequence of human chromosome 12.
16515701 2006 The effect of bisphosphonates on gene expression: GAPDH as a housekeeping or a new target gene?
16510976 2006 High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase.
16501887 2006 The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins.
16474839 2006 Glyceraldehyde 3-phosphate dehydrogenase is a SET-binding protein and regulates cyclin B-cdk1 activity.
16396496 2006 Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).
16289162 2006 The identification of myocilin-associated proteins in the human trabecular meshwork.
16239728 2005 Structural analysis of human liver glyceraldehyde-3-phosphate dehydrogenase.
16236267 2005 Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.
16186172 2005 Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease.
16169070 2005 A human protein-protein interaction network: a resource for annotating the proteome.
16139273 2005 Regulation of human erythrocyte glyceraldehyde-3-phosphate dehydrogenase by ferriprotoporphyrin IX.
16082386 2005 Glyceraldehyde 3-phosphate dehydrogenase serves as an accessory protein of the cardiac sarcolemmal K(ATP) channel.
16037232 2005 Methylglyoxal can modify GAPDH activity and structure.
15985219 2005 Identification of glyceraldehyde-3-phosphate dehydrogenase of epithelial cells as a second molecule that binds to Porphyromonas gingivalis fimbriae.
15976103 2005 Collection and storage of human blood cells for mRNA expression profiling: a 15-month stability study.
15952740 Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry.
15907785 2005 Degradation of glyceraldehyde-3-phosphate dehydrogenase triggered by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal.
15839736 2005 Differentiation of insulin-producing cells from human neural progenitor cells.
15769908 2005 GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues.
15746184 2005 Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein.
15716040 2005 Aging of human glyceraldehyde-3-phosphate dehydrogenase is dependent on its subcellular localization.
15680915 2005 Identification of major Ca(2+)/calmodulin-dependent protein kinase phosphatase-binding proteins in brain: biochemical analysis of the interaction.
15635413 2005 Nucleolar proteome dynamics.
15628863 2005 Oxidative stress-responsive intracellular regulation specific for the angiostatic form of human tryptophanyl-tRNA synthetase.
15592455 2005 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
15507493 2004 Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15485821 2004 Glyceraldehyde-3-phosphate dehydrogenase interacts with Rab2 and plays an essential role in endoplasmic reticulum to Golgi transport exclusive of its glycolytic activity.
15479637 2004 Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation.
15383276 2004 A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
15312048 2004 Interactions among p22, glyceraldehyde-3-phosphate dehydrogenase and microtubules.
15199064 2004 The muscle-specific calmodulin-dependent protein kinase assembles with the glycolytic enzyme complex at the sarcoplasmic reticulum and modulates the activity of glyceraldehyde-3-phosphate dehydrogenase in a Ca2+/calmodulin-dependent manner.
15001839 Cten mRNA expression is correlated with tumor progression in thymoma.
14760703 2004 Proteomic identification of brain proteins that interact with dynein light chain LC8.
14741744 2004 Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7.
14730345 2004 Thioredoxin, a regulator of gene expression.
14630908 2004 Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase.
14515148 2003 Modulation of GAPDH expression and cellular localization after vaccinia virus infection of human adherent monocytes.
12921788 2003 Glycolaldehyde induces apoptosis in a human breast cancer cell line.
12887926 2003 S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.
12842822 2003 Amino acid control of the human glyceraldehyde 3-phosphate dehydrogenase gene transcription in hepatocyte.
12842090 2003 Exportin 1-independent nuclear export of GAPDH.
12829261 2003 Subcellular localization of human glyceraldehyde-3-phosphate dehydrogenase is independent of its glycolytic function.
12753082 2003 Hydrogen peroxide induces association between glyceraldehyde 3-phosphate dehydrogenase and phospholipase D2 to facilitate phospholipase D2 activation in PC12 cells.
12697324 2003 HIF-2alpha regulates glyceraldehyde-3-phosphate dehydrogenase expression in endothelial cells.
12665801 2003 Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
12553051 Selection of an internal control gene for quantitation of mRNA in colonic tissues.
12519789 2003 Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.
12506084 2003 Effect of UVA light on the activity of several aged human lens enzymes.
12503091 2003 Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12428732 2002 Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?
12419855 2003 Effects of creatine supplementation on housekeeping genes in human skeletal muscle using real-time RT-PCR.
12381782 2002 Tubulin is the endogenous inhibitor of the glyceraldehyde 3-phosphate dehydrogenase isoform that catalyzes membrane fusion: Implications for the coordinated regulation of glycolysis and membrane fusion.
12200519 2002 beta-Actin and GAPDH housekeeping gene expression in asthmatic airways is variable and not suitable for normalising mRNA levels.
12140138 2002 Expression of estrogen receptors alpha and beta in human lung tissue and cell lines.
12121569 2002 Quantification of cyclin A1 and glyceraldehyde-3-phosphate dehydrogenase expression in testicular biopsies of infertile patients by fluorescence real-time RT-PCR.
12087577 2002 Can glomerular mRNAs in human type 1 diabetes be used to predict transition from normoalbuminuria to microalbuminuria?
11846445 2002 Glyceraldehyde-3-phosphate dehydrogenase associates with actin filaments in serum deprived NIH 3T3 cells only.
11735259 2001 Real-time RT-PCR for the detection of beta-adrenoceptor messenger RNAs in small human endomyocardial biopsies.
11724794 2002 Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway.
11488911 2001 Thermodynamics of the folding of D-glyceraldehyde-3-phosphate dehydrogenase assisted by protein disulfide isomerase studied by microcalorimetry.
11487543 2001 Intestinal epithelial cells secrete exosome-like vesicles.
11451542 2001 Increase of endothelial nitric oxide synthase and endothelin-1 mRNA expression in human placenta during gestation.
11157717 2001 Association of thrombospondin-1 and cardiac allograft vasculopathy in human cardiac allografts.
11011077 2000 HCV RNA levels in hepatocellular carcinomas and adjacent non-tumorous livers.
10944468 2000 cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.
10897012 2000 Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction.
10617673 2000 Reduced apoptosis after nerve growth factor and serum withdrawal: conversion of tetrameric glyceraldehyde-3-phosphate dehydrogenase to a dimer.
10407144 1999 Conformational structure and binding mode of glyceraldehyde-3-phosphate dehydrogenase to tRNA studied by Raman and CD spectroscopy.
10097256 1999 Expression of menin gene mRNA in pituitary tumours.
9886087 1999 Interactions of the C terminus of metabotropic glutamate receptor type 1alpha with rat brain proteins: evidence for a direct interaction with tubulin.
9308888 1997 A study on the complexes between human erythrocyte enzymes participating in the conversions of 1,3-diphosphoglycerate.
9110174 1997 Large-scale concatenation cDNA sequencing.
8872471 1996 Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase.
8650074 1996 There are multiple forms of glyceraldehyde-3-phosphate dehydrogenase in prostate cancer cells and normal prostate tissue.
8619474 1996 A "double adaptor" method for improved shotgun library construction.
8612237 1996 Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.
8473906 1993 Rat brain glyceraldehyde-3-phosphate dehydrogenase interacts with the recombinant cytoplasmic domain of Alzheimer's beta-amyloid precursor protein.
8451199 1993 Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in normal human cells.
8181459 1994 S-thiolation of human endothelial cell glyceraldehyde-3-phosphate dehydrogenase after hydrogen peroxide treatment.
8075252 1994 [Glycolytic enzymes in human erythrocytes: association of glyceraldehyde-3-phosphate dehydrogenase with 3-phosphoglycerate kinase].
7880402 1994 Organ culture of amniochorionic membrane in vitro.
7498159 1995 The major protein expression profile and two-dimensional protein database of human heart.
7144574 1982 Glyceraldehyde-3-phosphate dehydrogenase from human tissues.
7030790 1981 The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase.
6499844 1984 Characterization of the transcription products of glyceraldehyde 3-phosphate-dehydrogenase gene in HeLa cells.
6096821 1984 The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species.
6096136 1984 The glyceraldehyde 3 phosphate dehydrogenase gene family: structure of a human cDNA and of an X chromosome linked pseudogene; amazing complexity of the gene family in mouse.
6095107 1984 Unusual abundance of vertebrate 3-phosphate dehydrogenase pseudogenes.
3664468 1987 Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers.
3180054 1988 Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma.
3170585 1988 Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene.
3027061 1987 Identification of the 37-kDa protein displaying a variable interaction with the erythroid cell membrane as glyceraldehyde-3-phosphate dehydrogenase.
2987855 1985 Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene.
2793178 1989 Members of the human glyceraldehyde-3-phosphate dehydrogenase-related gene family map to dispersed chromosomal locations.
2394733 1990 An ATP-modulated specific association of glyceraldehyde-3-phosphate dehydrogenase with human erythrocyte glucose transporter.
1999197 1991 Characterization of the cell-cycle-regulated protein calcyclin from Ehrlich ascites tumor cells. Identification of two binding proteins obtained by Ca2(+)-dependent affinity chromatography.
1924305 1991 A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase.
1602151 1992 Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.
1193541 1975 The covalent structure of glyceraldehyde-phosphate dehydrogenase from human muscles. Isolation and amino acid sequences of peptides from tryptic digest.
957435 1976 Twinning in crystals of human skeletal muscle D-glyceraldehyde-3-phosphate dehydrogenase.