FSTL1
Follistatin-related protein 1
Protein Summary
May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity). This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]
- ENST00000295633
- ENSP00000295633
- ENSG00000163430
- ENST00000424703
- ENSP00000394355
- FRP
- FRP
- FSL1
- OCC1
- OCC-1
- tsc36
- MIR198
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.97 | ||
PubMedID | 0.96 | ||
kinase perturbation | 0.84 | ||
disease perturbation | 0.83 | ||
virus perturbation | 0.76 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 271.68 (req: < 5)
Gene RIFs: 100 (req: <= 3)
Antibodies: 352 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 271.68 (req: >= 5)
Gene RIFs: 100 (req: > 3)
Antibodies: 352 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0