| Tbio | Forkhead box protein Q1 |
Plays a role in hair follicle differentiation.
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Breast Neoplasms | 445 | 0.0 | 0.0 |
| Disease | Target Count |
|---|---|
| Mammary Neoplasms | 425 |
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6694 | 1.2e-08 |
| ovarian cancer | 8520 | 1.3e-08 |
| Astrocytoma, Pilocytic | 3081 | 5.1e-05 |
| pituitary cancer | 1972 | 1.4e-04 |
| adult high grade glioma | 3801 | 3.0e-04 |
| atypical teratoid / rhabdoid tumor | 5112 | 6.9e-04 |
| glioblastoma | 5792 | 7.6e-04 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 2.3e-03 |
| facioscapulohumeral dystrophy | 288 | 2.6e-03 |
| ependymoma | 4679 | 3.5e-03 |
| interstitial cystitis | 2312 | 4.1e-03 |
| lung adenocarcinoma | 2716 | 9.9e-03 |
| primitive neuroectodermal tumor | 3035 | 1.3e-02 |
| primary pancreatic ductal adenocarcinoma | 1109 | 1.3e-02 |
| active ulcerative colitis | 764 | 1.7e-02 |
| sonic hedgehog group medulloblastoma | 467 | 2.0e-02 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 3.4e-02 |
| spina bifida | 1074 | 3.6e-02 |
| invasive ductal carcinoma | 2951 | 4.3e-02 |
| astrocytic glioma | 2597 | 4.5e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Breast cancer | 3578 | 0.0 | 0.00102053358020131 |
| pancreatic cancer | 2398 | 0.0 | 4.19414102458195E-7 |
| Disease | log2 FC | p |
|---|---|---|
| Breast cancer | -1.100 | 1.0e-03 |
| pancreatic cancer | 2.100 | 4.2e-07 |
| active ulcerative colitis | 3.009 | 1.7e-02 |
| adult high grade glioma | -1.800 | 3.0e-04 |
| astrocytic glioma | -1.200 | 4.5e-02 |
| Astrocytoma, Pilocytic | -1.500 | 5.1e-05 |
| atypical teratoid / rhabdoid tumor | -1.300 | 6.9e-04 |
| ependymoma | -1.600 | 3.5e-03 |
| facioscapulohumeral dystrophy | -2.500 | 2.6e-03 |
| glioblastoma | -1.200 | 7.6e-04 |
| interstitial cystitis | -3.000 | 4.1e-03 |
| intraductal papillary-mucinous adenoma (... | 2.300 | 2.3e-03 |
| intraductal papillary-mucinous neoplasm ... | 1.900 | 3.4e-02 |
| invasive ductal carcinoma | 1.099 | 4.3e-02 |
| lung adenocarcinoma | 1.200 | 9.9e-03 |
| ovarian cancer | 4.000 | 1.3e-08 |
| pituitary cancer | -1.100 | 1.4e-04 |
| primary pancreatic ductal adenocarcinoma | 2.384 | 1.3e-02 |
| primitive neuroectodermal tumor | -1.300 | 1.3e-02 |
| psoriasis | -1.500 | 1.2e-08 |
| sonic hedgehog group medulloblastoma | -1.300 | 2.0e-02 |
| spina bifida | -2.701 | 3.6e-02 |
| Species | Source | Disease |
|---|---|---|
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid EggNOG |
MKLEVFVPRAAHGDKQGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDTQGDGEQSAGG 1 - 70 GPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRL 71 - 140 TLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFR 141 - 210 RRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAPAAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKP 211 - 280 FRSRRLRDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGEPARLGAREAEVPPTAPPLLL 281 - 350 APLPAAAPAKPLRGPAAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA 351 - 403 //
