Property Summary

NCBI Gene PubMed Count 16
PubMed Score 154.17
PubTator Score 15.60

Knowledge Summary


No data available

Gene RIF (7)

23965030 We found no evidence for a significant association between mutations of KCNJ10 and FOXI1 with SLC26A4 in Pendred syndrome/enlarged vestibular aqueducts.
22412181 No FOXI1 mutations were present in bilateral deafness patients with inner ear malformation.
20621367 SLC26A4, FOXI1 and KCNJ10 are not major determinants in unilateral deafness and enlarged vestibular aqueduct
20621367 Observational study of gene-disease association. (HuGE Navigator)
19214237 Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase complex at these locations.
18564921 Observational study of gene-disease association. (HuGE Navigator)
12695546 C/EBP alpha and HNF-3 gamma cooperatively regulate CYP3A4 expression in hepatic cells by a mechanism that probably involves chromatin remodeling.

AA Sequence

SVLSQFSPHFYNSVNTSGVLYPREGTEV                                              351 - 378

Text Mined References (16)

PMID Year Title
24927181 2014 Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
23965030 2013 Lack of significant association between mutations of KCNJ10 or FOXI1 and SLC26A4 mutations in Pendred syndrome/enlarged vestibular aqueducts.
23648065 2013 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
22412181 2012 Screening of SLC26A4, FOXI1, KCNJ10, and GJB2 in bilateral deafness patients with inner ear malformation.
20809947 2010 African signatures of recent positive selection in human FOXI1.
20621367 2010 Screening of SLC26A4, FOXI1 and KCNJ10 genes in unilateral hearing impairment with ipsilateral enlarged vestibular aqueduct.
19214237 2009 The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
18564921 2008 Candidate gene analysis in primary lymphedema.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12695546 2003 Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
9153225 1997 The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult mouse kidney.
8825632 1995 Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12).
7957066 1994 Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.
7683413 1993 Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.