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Tbio
FOXG1
Forkhead box protein G1

Protein Summary
Description
Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000313071
  • ENSP00000339004
  • ENSG00000176165

Symbol
  • FKH2
  • FKHL1
  • FKHL2
  • FKHL3
  • FKHL4
  • FOXG1A
  • FOXG1B
  • FOXG1C
  • BF1
  • BF2
  • QIN
  • FKH2
  • HBF2
  • HFK1
  • HFK2
  • HFK3
  • KHL2
  • FHKL3
  • FKHL1
  • FKHL2
  • FKHL3
  • FKHL4
  • HBF-1
  • HBF-2
  • HBF-3
  • FOXG1A
  • FOXG1B
  • FOXG1C
  • HBF-G2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.95
disease perturbation
0.79
PubMedID
0.76
hub protein
0.71
small molecule perturbation
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 906.63   (req: < 5)
Gene RIFs: 75   (req: <= 3)
Antibodies: 265   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 906.63   (req: >= 5)
Gene RIFs: 75   (req: > 3)
Antibodies: 265   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0