Property Summary

NCBI Gene PubMed Count 13
PubMed Score 20.85
PubTator Score 9.14

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (12)

Disease log2 FC p
nephrosclerosis -1.015 1.1e-02
posterior fossa group A ependymoma 1.600 2.5e-07
glioblastoma 2.000 9.1e-06
non diabetic and post-ischemic heart fai... 1.200 3.9e-03
atypical teratoid / rhabdoid tumor 1.900 8.6e-06
medulloblastoma 1.400 1.6e-03
medulloblastoma, large-cell 2.100 4.9e-06
active Crohn's disease -1.044 6.0e-03
adult high grade glioma 1.900 7.0e-04
pilocytic astrocytoma 1.300 2.0e-03
lung carcinoma -1.700 2.0e-27
ulcerative colitis -1.100 3.9e-05

Gene RIF (3)

PMID Text
20529763 Observational study of gene-disease association. (HuGE Navigator)
19898482 Observational study of gene-disease association. (HuGE Navigator)
19307449 Data show a compelling visual demonstration of the isoform-specific localization patterns of FMO1, -3, and -4 in the rat liver and kidney and the first evidence for expression of FMO4 at the protein level in mouse and human liver and kidney microsomes.

AA Sequence

MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYS      1 - 70
DFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVF     71 - 140
DAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQV    141 - 210
LLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAK    211 - 280
FIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIF    281 - 350
LYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVF    351 - 420
KDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQW    421 - 490
DRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLVRDKLQDRMSPYLVSLWRG      491 - 558
//

Text Mined References (14)

PMID Year Title
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
20529763 2010 Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.
19898482 2009 Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.
19307449 2009 Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and human liver and kidney microsomes.
16710414 2006 The DNA sequence and biological annotation of human chromosome 1.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12527699 2003 Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11551524 2001 Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.
8702731 1996 Expression and characterization of a modified flavin-containing monooxygenase 4 from humans.
8311461 1994 A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.
8128486 1994 The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression.
7720101 1995 The molecular biology of the flavin-containing monooxygenases of man.
1417778 1992 Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family.