Tbio FKBP7 Peptidyl-prolyl cis-trans isomerase FKBP7

Protein Summary

Description

PPIases accelerate the folding of proteins during protein synthesis. The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9Y680
• Q4ZG70
• Q6V3B2
• Q86U65
• Q96DA4
• Q9Y6B0
• PPIase FKBP7

Gene Name

• FKBP7

Ensembl ID

• ENST00000233092
• ENSP00000233092
• ENSG00000079150
• ENST00000424785
• ENSP00000413152
• ENST00000434643
• ENSP00000415486

Symbol

• FKBP23
• FKBP23
• PPIase

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.73
small molecule perturbation	0.66
transcription factor binding site profile	0.65
microRNA	0.61
cellular component	0.57

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 91.01   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 141   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 91.01   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 141   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0