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Tbio
FILIP1L
Filamin A-interacting protein 1-like

Protein Summary
Description
Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000331335
  • ENSP00000327880
  • ENSG00000168386
  • ENST00000354552
  • ENSP00000346560
  • ENST00000383694
  • ENSP00000373192
  • ENST00000398326
  • ENSP00000381371
  • ENST00000471562
  • ENSP00000419642
  • ENST00000487087
  • ENSP00000417774

Symbol
  • COL4A3BPIP
  • DOC1
  • GIP90
  • DOC1
  • DOC-1
  • GIP90
  • GIP130
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.91
small molecule perturbation
0.84
tissue sample
0.61
disease perturbation
0.56
virus perturbation
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.7   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 98   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.7   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 98   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0