Tchem | Free fatty acid receptor 2 |
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009]
Comments
Disease | Target Count | P-value |
---|---|---|
psoriasis | 6694 | 5.5e-46 |
ulcerative colitis | 1819 | 2.2e-03 |
interstitial cystitis | 2312 | 8.0e-03 |
Multiple Sclerosis | 540 | 2.5e-02 |
Rheumatoid arthritis | 1191 | 4.5e-02 |
Disease | log2 FC | p |
---|---|---|
interstitial cystitis | 1.200 | 8.0e-03 |
Multiple Sclerosis | 1.200 | 2.5e-02 |
psoriasis | 1.400 | 5.5e-46 |
Rheumatoid arthritis | 1.100 | 4.5e-02 |
ulcerative colitis | 2.000 | 2.2e-03 |
Species | Source | Disease |
---|---|---|
OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
OMA EggNOG |
compound 1 [PMID: 23589301]
- 7.10
trans-2-methylcrotonic acid
- 3.80
(S)-4-CMTB
- 6.40
CATPB
- 6.50
GLPG0974
pIC50 8.05
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAA 1 - 70 SNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGH 71 - 140 CTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQP 141 - 210 LVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVV 211 - 280 RRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE 281 - 330 //