Protein Summary
FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM, Mar 2008]
- ENST00000336830
- ENSP00000338598
- ENSG00000162746
- ENST00000367944
- ENSP00000356921
- ENST00000367945
- ENSP00000356922
- ENST00000367946
- ENSP00000356923
- ENST00000367948
- ENSP00000356925
- FCRL2
- FCRLM2
- FCRY
- FREB2
- FcRY
- FCRL2
- FCRLY
- FREB2
- FCRLM2
- FREB-2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.62 | ||
tissue sample | 0.56 | ||
tissue | 0.54 | ||
chemical | 0.41 | ||
protein domain | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.41 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 116 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.41 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 116 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0