Property Summary

NCBI Gene PubMed Count 6
PubMed Score 2.09
PubTator Score 2.08

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (14)

Disease log2 FC p
osteosarcoma -1.215 8.3e-06
ependymoma -1.500 1.6e-06
glioblastoma -2.200 1.5e-05
medulloblastoma -1.700 3.3e-04
atypical teratoid / rhabdoid tumor -1.900 9.1e-05
medulloblastoma, large-cell -2.600 4.6e-05
primitive neuroectodermal tumor -1.600 1.3e-04
tuberculosis and treatment for 6 months 1.100 1.5e-05
intraductal papillary-mucinous adenoma (... 1.400 6.2e-04
intraductal papillary-mucinous carcinoma... 1.300 3.1e-03
adult high grade glioma -2.400 2.1e-05
pilocytic astrocytoma -1.200 1.9e-03
spina bifida -1.068 3.0e-02
ovarian cancer -1.200 1.7e-05

Synonym

Accession Q7Z6M2 Q6PIR2 Q86TR2 Q86YE0
Symbols Fbx33
BMND12
c14_5247

Gene

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 GO Process (1)

 Compartment GO Term (1)

Gene RIF (2)

PMID Text
25284319 This study findings show tentative evidence for the involvement of FBXO33 in the susceptibility to adult attention-deficit hyperactivity disorder.
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

AA Sequence

MLLFLSVPQPRPPGARTRAGAARVARWRRLRLQQLRRLRGLLRVLRGRPGAGSRRRGRMALCGQAAGAAS      1 - 70
LPSELIVHIFSFLPAPDRLRASASCSHWRECLFYPALWPQLRICLRVSPAEQPRLEFLMRKCGWFVRELR     71 - 140
VEFAAENYLSGGGPGDGGGADTGTGGEEVEALQLSARWLEVLRTYLELVLCVLVSIRNNRNLQKFSLFGD    141 - 210
ISVLQQQGSLSNTYLSKVDPDGKKIKQIQQLFEEILSNSRQLKWLSCGFMLEIVTPTSLSSLSNAVANTM    211 - 280
EHLSLLDNNIPGNSTLITAVELERFVNLHSLALDFCDFTAEMARVLTDSNHVPLQRLSLLVHNVSVMHKS    281 - 350
LDNMPNDEHWKALSRKSTSFRVYIMAFDIKSEDMLKILKPSIPLERIHFDSYITCVSGAIVDLISRQYDK    351 - 420
FLTHFILMNDVIDTSGFPDLSDNRNEDPLVLLAWRCTKLSLLAIHGYTVWAHNLIAIARLRGSDLKVLEV    421 - 490
TEESIDFDQGELADQDVDPVHNLIEQVSLGLGQPWHAVMDIESLSVFTEPNRHFYREMQSFSEDI         491 - 555
//

Text Mined References (6)

PMID Year Title
25284319 2015 Case-control genome-wide association study of persistent attention-deficit hyperactivity disorder identifies FBXO33 as a novel susceptibility gene for the disorder.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
16797541 2006 Proteasomal degradation of the multifunctional regulator YB-1 is mediated by an F-Box protein induced during programmed cell death.
15520277 2004 Systematic analysis and nomenclature of mammalian F-box proteins.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.