Protein FAM222A

Property Summary

NCBI Gene PubMed Count	3
PubMed Score	0.00

Knowledge Summary

Patent

No data available

TINX Plot

Disease (1)

Expression Atlas

Disease	Target Count	P-value
ependymoma	4679	3.6e-06
atypical teratoid/rhabdoid tumor	357	8.3e-05
subependymal giant cell astrocytoma	2287	3.2e-03
adult high grade glioma	3801	4.7e-02

Expression

Specificity
Differential

Differential Expression (4)

Disease	log2 FC	p
adult high grade glioma	-1.100	4.7e-02
atypical teratoid/rhabdoid tumor	-1.500	8.3e-05
ependymoma	-1.500	3.6e-06
subependymal giant cell astrocytoma	-2.043	3.2e-03

Brain - Spinal cord (cervical c-1) 17,973

Testis 18,518

Pituitary 18,147

Brain - Cerebellum 17,983

Adrenal Gland 18,071

Brain - Substantia nigra 17,981

Brain - Putamen (basal ganglia) 17,863

Ovary 17,971

Brain - Hypothalamus 18,169

Brain - Cerebellar Hemisphere 18,015

Brain - Caudate (basal ganglia) 18,001

Brain - Hippocampus 18,011

Nerve - Tibial 18,007

Brain - Nucleus accumbens (basal ganglia... 18,024

Spleen 17,614

Brain - Cortex 18,039

Brain - Amygdala 18,006

Brain - Frontal Cortex (BA9) 18,069

Skin - Sun Exposed (Lower leg) 17,968

Kidney - Cortex 17,329

Brain - Anterior cingulate cortex (BA24) 17,989

Heart - Atrial Appendage 17,896

Skin - Not Sun Exposed (Suprapubic) 18,081

Small Intestine - Terminal Ileum 17,954

Stomach 17,879

Lung 18,057

Colon - Sigmoid 18,089

Minor Salivary Gland 18,005

Prostate 18,213

Esophagus - Muscularis 18,017

Vagina 17,834

Heart - Left Ventricle 18,006

Esophagus - Gastroesophageal Junction 18,000

Liver 18,071

Esophagus - Mucosa 18,076

Pancreas 18,123

Muscle - Skeletal 17,778

Artery - Coronary 17,949

Thyroid 18,024

Breast - Mammary Tissue 18,103

Colon - Transverse 17,825

Uterus 17,618

Adipose - Visceral (Omentum) 17,937

Artery - Aorta 17,896

Whole Blood 17,439

Adipose - Subcutaneous 18,110

Artery - Tibial 17,631

Cells - Transformed fibroblasts 17,577

Cells - EBV-transformed lymphocytes 18,186

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

pancreas 14,070

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

See source...

Synonym

Accession	Q5U5X8 Q8NCD5 Q96SP6
Symbols	C12orf34

Gene

FAM222A

Ortholog (9)

Species	Source	Disease
Rat 15,112	Inparanoid OMA EggNOG
Dog 15,069	Inparanoid OMA EggNOG
Cow 15,316	OMA EggNOG
Pig 10,164	OMA EggNOG
Opossum 12,223	Inparanoid OMA EggNOG
Xenopus 10,463	OMA EggNOG
Zebrafish 9,725	Inparanoid OMA EggNOG
Chimp 14,136	OMA EggNOG
Mouse 16,567	Inparanoid OMA EggNOG

UniProt Keyword (2)

Complete proteome 20,231

Reference proteome 20,231

Compartment GO Term (4)

Focal adhesion sites 125

Mitochondria 998

Nucleoplasm 5,077

Plasma membrane 5,830

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

Protein-protein Interaction (7)

MAB21L1 NLK PBX1 PBX2 PBX3 MEIS1 MEIS2

AA Sequence

MLACLQRTQNAPGQHLACPSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSIKIFPTNIRVP      1 - 70
QHKHLSRTVNGYDTSGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAA     71 - 140
VQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQC    141 - 210
QAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYAD    211 - 280
SGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWN    281 - 350
SVLVTPTSDCYNPAAAVVVTELGPGAARELAGPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIRPPC    351 - 420
IKEQMLGKGYETVAVPRLLDHQHAHIRLPVYR                                          421 - 452
//

	PMID	Year	Title

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