Tbio EPS8L3 Epidermal growth factor receptor kinase substrate 8-like protein 3

Protein Summary

Description

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q8TE67
• A8K833
• Q5T8Q6
• Q5T8Q7
• Q5T8Q8
• Q96E47
• Q9H719
• EPS8-like protein 3

Gene Name

• EPS8L3

Ensembl ID

• ENST00000361852
• ENSP00000354551
• ENSG00000198758
• ENST00000361965
• ENSP00000355255
• ENST00000369805
• ENSP00000358820

Symbol

• EPS8R3
• EPS8R3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.71
cell line	0.53
cell type or tissue	0.44
chemical	0.44
transcription factor	0.43

Protein Classes

PANTHER Classes

Protein / Transmembrane Receptor Regulatory/adaptor Protein / Epidermal Growth Factor Receptor Kinase Substrate 8-like Protein 3

DTO Classes

Protein / Receptor / Epidermal Growth Factor Receptor Kinase Substrate 8-like Protein 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.73   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 134   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.73   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 134   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0