Tbio GALK1 Galactokinase

Protein Summary

Description

Major enzyme for galactose metabolism. Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• P51570
• B2RC07
• B4E1G6

Gene Name

• GALK1

Ensembl ID

• ENST00000225614
• ENSP00000225614
• ENSG00000108479
• ENST00000588479
• ENSP00000465930

Symbol

• GALK
• GK1
• GALK
• HEL-S-19

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.99
interacting protein	0.94
molecular function	0.94
small molecule perturbation	0.8
transcription factor perturbation	0.8

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Carbohydrate Kinase / Galactokinase

DTO Classes

Protein / Kinase / Unclassified Protein / Galactokinase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 729.64   (req: < 5)

Gene RIFs: 26   (req: <= 3)

Antibodies: 258   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 729.64   (req: >= 5)

Gene RIFs: 26   (req: > 3)

Antibodies: 258   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0