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Tbio
JKAMP
JNK1/MAPK8-associated membrane protein

Protein Summary
Description
May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261247
  • ENSP00000261247
  • ENSG00000050130
  • ENST00000356057
  • ENSP00000348351
  • ENST00000425728
  • ENSP00000389699

Symbol
  • C14orf100
  • JAMP
  • JAMP
  • CDA06
  • HSPC213
  • HSPC327
  • C14orf100
  • C24orf100
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
transcription factor perturbation
0.84
histone modification site profile
0.81
transcription factor binding site profile
0.68
tissue sample
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.08   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.08   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0