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Tbio
CHI3L2
Chitinase-3-like protein 2

Protein Summary
Description
Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity. The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369744
  • ENSP00000358759
  • ENSG00000064886
  • ENST00000369748
  • ENSP00000358763
  • ENST00000445067
  • ENSP00000437082
  • ENST00000466741
  • ENSP00000437086
  • ENST00000524472
  • ENSP00000432049

Symbol
  • CHIL2
  • YKL39
  • YKL-39
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.9
protein domain
0.85
cell type or tissue
0.73
disease perturbation
0.49
small molecule perturbation
0.49


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 62.18   (req: < 5)
Gene RIFs: 21   (req: <= 3)
Antibodies: 206   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 62.18   (req: >= 5)
Gene RIFs: 21   (req: > 3)
Antibodies: 206   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0