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Tbio
ACER3
Alkaline ceramidase 3

Protein Summary
Description
Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000532485
  • ENSP00000434480
  • ENSG00000078124

Symbol
  • APHC
  • PHCA
  • APHC
  • PHCA
  • PLDECO
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.88
histone modification site profile
0.86
transcription factor binding site profile
0.65
cell type or tissue
0.57
tissue
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 142.05   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 142.05   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0