Tbio EVX1 Homeobox even-skipped homolog protein 1

Protein Summary

Description

May play a role in the specification of neuronal cell types. This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded protein may play an important role as a transcriptional repressor during embryogenesis. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• P49640
• A4D199
• B4DQJ0

Gene Name

• EVX1

Ensembl ID

• ENST00000496902
• ENSP00000419266
• ENSG00000106038

Symbol

• EVX-1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.76
PubMedID	0.64
transcription factor	0.62
protein domain	0.58
transcription factor binding site profile	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.47   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 150   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.47   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 150   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0