Tbio ODAPH Odontogenesis associated phosphoprotein

Protein Summary

Description

May promote nucleation of hydroxyapatite. Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene is thought to encode an extracellular matrix acidic phosphoprotein that has a function in enamel mineralization during amelogenesis. Mutations in this gene are associated with recessive hypomineralized amelogenesis imperfecta. [provided by RefSeq, Oct 2012]

Uniprot Accession IDs

• Q17RF5
• B4DTI3
• E7ETQ0
• Q8TEC3

Gene Name

• ODAPH

Ensembl ID

• ENST00000311623
• ENSP00000311307
• ENSG00000174792
• ENST00000435974
• ENSP00000406925

Symbol

• C4orf26
• AI2A4
• C4orf26

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.76   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 31   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.76   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0