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Tbio
MXRA8
Matrix remodeling-associated protein 8

Protein Summary
Description
May play a role in the maturation and maintenance of blood-brain barrier. (Microbial infection) Contributes to arthritogenic alphavirus pathogenesis and acts as a receptor for these viruses.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309212
  • ENSP00000307887
  • ENSG00000162576
  • ENST00000342753
  • ENSP00000344998
  • ENST00000445648
  • ENSP00000399229
  • ENST00000477278
  • ENSP00000436135

Symbol
  • ASP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.96
kinase perturbation
0.84
gene perturbation
0.68
cell type or tissue
0.62
small molecule perturbation
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 259.59   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 14   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 259.59   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 14   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0