Tbio ATP2C2 Calcium-transporting ATPase type 2C member 2

Protein Summary

Description

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.

Uniprot Accession IDs

• O75185
• B4DU76
• E7ES94
• Q5HYC3
• Q5S053
• Q68CQ2
• ATPase 2C2

Gene Name

• ATP2C2

Ensembl ID

• ENST00000262429
• ENSP00000262429
• ENSG00000064270
• ENST00000416219
• ENSP00000397925

Symbol

• KIAA0703
• SPCA2
• SPCA2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	1
protein domain	1
gene perturbation	0.8
cell type or tissue	0.66
disease perturbation	0.62

Protein Classes

PANTHER Classes

Protein / Transporter / Ion Channel / Calcium-transporting Atpase Type 2c Member 2

Protein / Transporter / Cation Transporter / Calcium-transporting Atpase Type 2c Member 2

Protein / Hydrolase / Calcium-transporting Atpase Type 2c Member 2

DTO Classes

Protein / Transporter / P-type Atpases / Ca2+-atpases / Calcium-transporting Atpase Type 2c Member 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.7   (req: < 5)

Gene RIFs: 20   (req: <= 3)

Antibodies: 51   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.7   (req: >= 5)

Gene RIFs: 20   (req: > 3)

Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0