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Tbio
GLYCTK
Glycerate kinase

Protein Summary
Description
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305690
  • ENSP00000301965
  • ENSG00000168237
  • ENST00000436784
  • ENSP00000389175
  • ENST00000473032
  • ENSP00000418951
  • ENST00000477382
  • ENSP00000419008

Symbol
  • HBEBP4
  • HBEBP2
  • HBEBP4
  • HBeAgBP4A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
transcription factor
0.76
transcription factor binding site profile
0.69
virus perturbation
0.68
histone modification site profile
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.15   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 245   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.15   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 245   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0