ATXN2L
Ataxin-2-like protein
Protein Summary
Involved in the regulation of stress granule and P-body formation. This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- ENST00000325215
- ENSP00000315650
- ENSG00000168488
- ENST00000336783
- ENSP00000338718
- ENST00000340394
- ENSP00000341459
- ENST00000382686
- ENSP00000372133
- ENST00000395547
- ENSP00000378917
- ENST00000570200
- ENSP00000454516
- A2D
- A2LG
- A2LP
- A2RP
- A2D
- A2LG
- A2LP
- A2RP
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
drug perturbation | 1 | ||
interacting protein | 0.98 | ||
transcription factor binding site profile | 0.94 | ||
ligand (protein) perturbation | 0.83 | ||
transcription factor | 0.81 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 71.66 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 107 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 71.66 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 107 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0