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Tbio
HYDIN
Hydrocephalus-inducing protein homolog

Protein Summary
Description
Required for ciliary motility. This gene encodes a protein that may be involved in cilia motility. Mutations in this gene cause of autosomal recessive primary ciliary dyskinesia-5, a disorder characterized by the accumulation of cerebrospinal fluid within the ventricles of the brain. A duplicate copy of this gene has been found in humans on chromosome 1. [provided by RefSeq, Jan 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321489
  • ENSP00000314736
  • ENSG00000157423
  • ENST00000393567
  • ENSP00000377197
  • ENST00000538248
  • ENSP00000444970
  • ENST00000541601
  • ENSP00000437341
  • ENST00000634268
  • ENSP00000489181
  • ENSG00000283022
  • ENST00000634392
  • ENSP00000489221
  • ENST00000634745
  • ENSP00000489246
  • ENST00000635381
  • ENSP00000489526

Symbol
  • HYDIN1
  • KIAA1864
  • CILD5
  • HYDIN1
  • HYDIN2
  • PPP1R31
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.68
kinase perturbation
0.6
transcription factor
0.56
histone modification site profile
0.52
microRNA
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.53   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 40   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.53   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0