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Tbio
CPPED1
Serine/threonine-protein phosphatase CPPED1

Protein Summary
Description
Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261660
  • ENSP00000261660
  • ENSG00000103381
  • ENST00000381774
  • ENSP00000371193
  • ENST00000433677
  • ENSP00000411127

Symbol
  • CSTP1
  • CSTP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor binding site profile
0.78
histone modification site profile
0.74
cell type or tissue
0.7
tissue sample
0.67


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.72   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 129   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.72   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 129   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0