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Tbio
RPP40
Ribonuclease P protein subunit p40

Protein Summary
Description
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319533
  • ENSP00000317998
  • ENSG00000124787
  • ENST00000380051
  • ENSP00000369391

Symbol
  • RNASEP1
  • RNASEP1
  • bA428J1.3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
kinase perturbation
0.81
virus perturbation
0.76
tissue sample
0.65
transcription factor binding site profile
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.65   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.65   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0