You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
MKX
Homeobox protein Mohawk

Protein Summary
Description
May act as a morphogenetic regulator of cell adhesion. The protein encoded by this gene is an IRX family-related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jun 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375790
  • ENSP00000364946
  • ENSG00000150051
  • ENST00000419761
  • ENSP00000400896

Symbol
  • C10orf48
  • IRXL1
  • IFRX
  • IRXL1
  • C10orf48
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.88
biological process
0.81
PubMedID
0.64
kinase perturbation
0.6
microRNA
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.55   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 198   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.55   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 198   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0