Tbio TAS1R2 Taste receptor type 1 member 2

Protein Summary

Description

Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.

Uniprot Accession IDs

• Q8TE23
• Q5TZ19

Gene Name

• TAS1R2

Ensembl ID

• ENST00000375371
• ENSP00000364520
• ENSG00000179002

Symbol

• GPR71
• T1R2
• TR2
• TR2
• T1R2
• GPR71

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.85
tissue	0.71
tissue sample	0.71
cell type or tissue	0.56
cell line	0.5

Protein Classes

PANTHER Classes

Protein / Transporter / Ion Channel / Ligand-gated Ion Channel / Ionotropic Glutamate Receptor / Taste Receptor Type 1 Member 2

Protein / Receptor / Ligand-gated Ion Channel / Ionotropic Glutamate Receptor / Taste Receptor Type 1 Member 2

Protein / Receptor / G-protein Coupled Receptor / Taste Receptor Type 1 Member 2

DTO Classes

Protein / G-protein Coupled Receptor / Class C Metabotropic Glutamate/pheromone / Taste 1 Receptor / Taste Receptor Type 1 Member 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 215.71   (req: < 5)

Gene RIFs: 34   (req: <= 3)

Antibodies: 185   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 215.71   (req: >= 5)

Gene RIFs: 34   (req: > 3)

Antibodies: 185   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0