Tbio PPP3R2 Calcineurin subunit B type 2

Protein Summary

Description

Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

Uniprot Accession IDs

• Q96LZ3
• Q5VTR4
• Q7Z4V8
• Q8WYJ4

Gene Name

• PPP3R2

Ensembl ID

• ENST00000374806
• ENSP00000363939
• ENSG00000188386

Symbol

• CBLP
• PPP3RL
• PPP3RL

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	0.61
disease perturbation	0.56
cell type or tissue	0.55
microRNA	0.54
gene perturbation	0.5

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 112.99   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 162   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 112.99   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 162   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0