Protein Summary
Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission. This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1. [provided by RefSeq, Jul 2008]
- ENST00000238341
- ENSP00000238341
- ENSG00000119397
- ENST00000373850
- ENSP00000362956
- ENST00000373855
- ENSP00000362962
- ENST00000613863
- ENSP00000481072
- CEP1
- CEP110
- FAN
- CEP1
- CEP110
- bA165P4.1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.81 | ||
cell line | 0.69 | ||
cellular component | 0.68 | ||
pathway | 0.65 | ||
interacting protein | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 92.55 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 26 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 92.55 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 26 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0