Tbio FOXJ3 Forkhead box protein J3

Protein Summary

Description

Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration.

Uniprot Accession IDs

• Q9UPW0
• A7MBL7
• A7MD18
• D3DPW2
• Q9NSS7

Gene Name

• FOXJ3

Ensembl ID

• ENST00000361346
• ENSP00000354620
• ENSG00000198815
• ENST00000361776
• ENSP00000354449
• ENST00000372572
• ENSP00000361653
• ENST00000372573
• ENSP00000361654
• ENST00000545068
• ENSP00000439044

Symbol

• KIAA1041

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.88
transcription factor binding site profile	0.87
microRNA	0.78
co-expressed gene	0.72
transcription factor	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.43   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 174   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.43   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 174   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0