You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
NFIA
Nuclear factor 1 A-type

Protein Summary
Description
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371187
  • ENSP00000360229
  • ENSG00000162599
  • ENST00000371189
  • ENSP00000360231
  • ENST00000403491
  • ENSP00000384523
  • ENST00000407417
  • ENSP00000384680

Symbol
  • KIAA1439
  • CTF
  • NF1-A
  • NFI-A
  • NFI-L
  • BRMUTD
  • NF-I/A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.96
transcription factor
0.96
kinase perturbation
0.88
PubMedID
0.87
transcription factor binding site profile
0.82


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 164.66   (req: < 5)
Gene RIFs: 48   (req: <= 3)
Antibodies: 235   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 164.66   (req: >= 5)
Gene RIFs: 48   (req: > 3)
Antibodies: 235   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0