Tdark SLC22A15 Solute carrier family 22 member 15

Protein Summary

Description

Probably transports organic cations (By similarity). Appears not to be the agmatine transporter. Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).[supplied by OMIM, Apr 2004]

Uniprot Accession IDs

• Q8IZD6
• A8MUR3
• Q6UXP5
• Q8TAL9
• Q9NSH5

Gene Name

• SLC22A15

Ensembl ID

• ENST00000369502
• ENSP00000358514
• ENSG00000163393
• ENST00000369503
• ENSP00000358515

Symbol

• FLIPT1
• FLIPT1
• PRO34686

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.73
histone modification site profile	0.69
microRNA	0.55
PubMedID	0.53
tissue sample	0.52

Protein Classes

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc22 Family Of Organic Cation And Anion Transporters / Orphan Or Poorly Characterized Slc22 Family Members / Solute Carrier Family 22 Member 15

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.74   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 66   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.74   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 66   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0