Protein Summary
Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis.
- ENST00000271883
- ENSP00000271883
- ENSG00000116580
- ENST00000361040
- ENSP00000354322
- ENST00000368331
- ENSP00000357315
- ENST00000437809
- ENSP00000396117
- ENST00000615926
- ENSP00000483100
- GON4
- KIAA1606
- GON4
- YARP
- GON-4
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.95 | ||
virus perturbation | 0.68 | ||
kinase perturbation | 0.66 | ||
tissue sample | 0.64 | ||
cell line | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 27.13 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 13 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 27.13 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 13 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0