Tbio ERGIC2 Endoplasmic reticulum-Golgi intermediate compartment protein 2

Protein Summary

Description

Possible role in transport between endoplasmic reticulum and Golgi. ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]

Uniprot Accession IDs

• Q96RQ1
• A6NHH6
• Q53GY2
• Q8N2Q9
• Q9BVV9
• Q9NZA3

Gene Name

• ERGIC2

Ensembl ID

• ENST00000360150
• ENSP00000353270
• ENSG00000087502

Symbol

• ERV41
• PTX1
• PTX1
• CDA14
• Erv41
• cd002

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.84
transcription factor perturbation	0.84
histone modification site profile	0.79
cellular component	0.76
interacting protein	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.23   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 184   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.23   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 184   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0