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Tbio
DDA1
DET1- and DDB1-associated protein 1

Protein Summary
Description
May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359866
  • ENSP00000352928
  • ENSG00000130311
  • ENST00000593466
  • ENSP00000473086
  • ENST00000596582
  • ENSP00000472171

Symbol
  • C19orf58
  • PCIA1
  • PCIA1
  • C19orf58
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.93
kinase perturbation
0.84
tissue
0.72
tissue sample
0.71
cell type or tissue
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.11   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 160   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.11   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 160   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0