Tbio TSGA10 Testis-specific gene 10 protein

Protein Summary

Description

Plays a role in spermatogenesis (PubMed:28905369). When overexpressed, prevents nuclear localization of HIF1A (By similarity).

Uniprot Accession IDs

• Q9BZW7
• B7Z925
• D3DVH7
• Q8NEP0
• Q9BWX0

Gene Name

• TSGA10

Ensembl ID

• ENST00000355053
• ENSP00000347161
• ENSG00000135951
• ENST00000393483
• ENSP00000377123
• ENST00000410001
• ENSP00000386956

Symbol

• CEP4L
• CT79
• CEP4L
• SPGF26

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.9
transcription factor binding site profile	0.87
transcription factor	0.8
tissue sample	0.71
cell type or tissue	0.59

Protein Classes

PANTHER Classes

Protein / Viral Protein / Testis-specific Gene 10 Protein

Protein / Enzyme Modulator / Kinase Modulator / Testis-specific Gene 10 Protein

DTO Classes

Protein / Enzyme Modulator / Kinase Modulator / Testis-specific Gene 10 Protein

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.09   (req: < 5)

Gene RIFs: 18   (req: <= 3)

Antibodies: 127   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.09   (req: >= 5)

Gene RIFs: 18   (req: > 3)

Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0