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Tbio
LUC7L2
Putative RNA-binding protein Luc7-like 2

Protein Summary
Description
May bind to RNA via its Arg/Ser-rich domain. This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263545
  • ENSP00000263545
  • ENSG00000146963
  • ENST00000354926
  • ENSP00000347005
  • ENST00000541170
  • ENSP00000441604
  • ENST00000619796
  • ENSP00000483438

Symbol
  • CGI-59
  • CGI-74
  • LUC7B2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.99
transcription factor perturbation
0.99
disease perturbation
0.95
kinase perturbation
0.93
virus perturbation
0.92


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.28   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 124   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.28   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 124   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0